5 research outputs found

    Ultrastructural, Histochemical, and Cytological Study of Testis of Human Fetuses of Various Gestation Periods with Future Implications in Orchidectomy / Orchidopexy in the Patients with Seminoma and Interstitial Cell Tumors of Testis

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    Background & Aims:  The immunohistological and ultrastructural features of the human testis with emphasis upon the process of spermatogenesis and the cytology of the Leydig cells were reviewed in this study. The present study also has its future implications in staging of cancer metastasis in the patients with Seminoma Testis and Leydig Cell Tumors and also in future xenografting of testicular tissue from an infant human donor. Materials & Methods:  The testis tissue samples from aborted human fetuses of various weeks of gestation were taken and then subjected to immunohistochemistry by Ki-67 antibodies and also to Scanning Electron Microscopy and Transmission Electron Microscopy. Results:  In the ultrastructural study, it is shown that the seminiferous epithelium is structurally partitioned by the Sertoli cells into basal and adluminal compartments via the specialized tight junctions between the Sertoli cells. The Leydig cell cytoplasm contains an abundant supply of smooth endoplasmic reticulum and mitochondria with tubular cristae, both features being characteristic of steroidogenic cells. Conclusion:  The detailed ultrastructural study can help the surgeons in the future xenografting processes of testicular tissue from an infant human donor to increase sperm maturity because of highly vascular testicular tissue

    Study of fine needle aspiration cytology evaluation of peripheral lymph nodes

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    Introduction: Lymph nodes are an integral component of the immune system and their enlargement is commonly noted in clinical practice in a wide spectrum of diseases, including infections like tuberculosis and malignancy. FNAC is an important diagnostic tool for rapid evaluation of mainly superficial lesions, especially of lymph nodes. It is cost effective, relatively less traumatic, and enables the pathologist to provide the clinician with a diagnosis in a very short time, and hence is ideal especially for OPD patients. Objectives: 1. To study the age and sex distribution of the patients of FNAC of peripheral lymph node. 2. To study the spectrum of diseases diagnosed on FNAC of peripheral lymph nodes. Methods: Cross-sectional hospital based Observational study. Total 50 patients who had superficial lymphadenopathy were included in this study. Male patients were 21 (42%) and Female patients were 29 (58%). FNAC was performed on this 50 patients. Diagnosis was made by light Microscopy. Result was tabulated and statistical analysis was done. Results: Male patients were 21 (42%) and Female patients were 29 (58%). 50 % patients were in the age group of 21 to 40 years. Reactive hyperplasia was 46% and Granulomatous lymphadenitis was 18%. Cervical lymph nodes were most commonly involved. Conclusion: FNAC is a simple, quick, low cost, minimally invasive and easy diagnostic procedure which is very much helpful in the diagnosis of diseases causing superficial lymphadenopathy in all age groups. Reactive hyperplasia of lymph node was the most common cytological diagnosis followed by Granulomatous lymphadenitis

    PREVALENCE OF HYPERTENSION AND DIABETES MELLITUS AMONG GROUP C AND GROUP D STAFFS IN A RURAL MEDICAL COLLEGE AND HOSPITAL, INDIA

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    Objective: Our aim of this study is to assess prevalence of hypertension and diabetes among Group C and Group D staffs in a Rural Medical College and Hospital of West Bengal, India as well as to assess whether there is difference of these parameters among two groups. Methods: After getting clearance from the Institutional Ethics Committee, this cross-sectional observational unicentric study was done with 44 Group C Staffs and 80 Group D staffs. Results: The study showed that the prevalence of hypertension among the staffs was 8.87% and the prevalence of diabetes mellitus among the staffs was 6.45%. The difference of mean blood sugar among two groups of staffs was not significant, but the difference of mean blood pressure was significant among two groups. Conclusion: As the study involved the health status of important staffs of medical teaching institutes, it will help to implement healthy lifestyle to avoid development of hypertension and diabetes in future among different categories of staffs

    Reflections on co-ordinating peer-assisted learning in a university mathematics department

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    This reflective paper explores the experience of the author while co-ordinating a relaunch of Peer-Assisted Learning (PAL) within the Department of Mathematical Sciences at a UK university. PAL involves senior students supporting first-year students through regular collaborative learning sessions, fostering both academic engagement and peer mentoring. The paper discusses the practical challenges encountered during implementation, such as student participation, scheduling, and training of PAL leaders, alongside the strategies that proved effective. Drawing on these experiences, the author will suggest potential improvements to enhance the impact of PAL in future iterations. The insights shared may be of value to other academics looking to introduce or refine similar peer-support initiatives in their own departments

    High-Performance and Scalable Aqueous Na-Ion Batteries Comprising a Co-Prussian Blue Analogue Framework Positive Electrode and Sodium Vanadate Nanorod Negative Electrode for Solar Energy Storage

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    A unique configuration of aqueous Na-ion batteries is investigated for solar energy storage, where single-wall carbon nanotube (SWCNT)-coated stainless steel (SS304), Co-Prussian blue analogue (Co-PBA/Na2CoFe(CN)6), and sodium vanadate (NVO/NaV3O8) nanorods are employed as a current collector, positive active material, and negative active material, respectively. The SWCNT coverage on SS radically obstructs the metallic corrosion under anodic polarization and also enhances the electrolyte stability window by preventing direct contact between the metal substrate and electrolyte. Both the positive and negative materials are structurally analyzed by Rietveld refinement of powder X-ray diffraction data. The Co-PBA framework structure demonstrates one-dimensional channels with ∼5.3 and 5.1 Å widths along [100] and [011], respectively, whereas the layered NVO depicts an interlayer spacing of ∼4.2 Å for facile Na-ion transportations. Resultantly, the high diffusion coefficients of Na-ions in Co-PBA and NVO are achieved as 1.6 × 10–13 and 2.0 × 10–11 cm2 s–1, respectively. Both Co-PBA and NVO exhibit a diffusion-controlled Faradaic charge storage mechanism, which has been demonstrated by cyclic voltammetry. The Co-PBA provides 122 mAh g–1 specific capacity at 1C rate, which is the highest reported value in aqueous medium with low-cost current collectors. The electrochemical performance testing of NaV3O8 is first described by us, explicitly for the negative electrode, and it delivers 83 mAh g–1 specific capacity at 1C. The 1.5 V silica gel-based Co-PBA//NVO full cell is fabricated with mass balancing, which shows higher cell voltage by maximizing the water splitting window. The full cell delivers a specific capacity of 141 mAh g–1 (@ 1C), an energy density of 211 Wh kg–1 (@ 250 W kg–1), a power density of 2466 W kg–1 (@ 94 Wh kg–1), and good durability (80% capacity retention @ 5C) up to 500 cycles. A 3 V/5 mAh rated prototype device is assembled, and it delivers satisfactory solar energy storage performances under 1 week of continuous operation
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