321 research outputs found
Reliable Change Formula Query: Temkin et al. reply
Hinton-Bayre (2000) raises a point that may occur
to many readers who are familiar with the Reliable Change
Index (RCI). In our previous paper comparing four models
for detecting significant change in neuropsychological
performance (Temkin et al., 1999), we used a formula for
calculating Sdiff, the measure of
variability for the test–retest difference, that
differs from the one Hinton-Bayre has seen employed in
other studies of the RCI. In fact, there are two ways
of calculating Sdiff—a direct
method and an approximate method. As stated by Jacobson
and Truax (1991, p. 14), the direct method is to compute
“the standard error of the difference between the
two test scores” or equivalently
[begin square root](s12 +
s22 − 2s1s2rxx′)[end square root]
where si is the standard deviation at
time i and rxx′ is the
test–retest correlation or reliability coefficient.
Jacobson and Truax also provide a formula for the approximation
of Sdiff when one does not have access
to retest data on the population of interest, but does have a
test–retest reliability coefficient and an estimate
of the cross-sectional standard deviation, i.e., the standard
deviation at a single point in time. This approximation assumes
that the standard deviations at Time 1 and Time 2 are equal,
which may be close to true in many cases. Since we had the
longitudinal data to directly calculate the standard error of
the difference between scores at Time 1 and Time 2, we used the
direct method. Which method is preferable? When the needed data
are available, it is the one we used.</jats:p
Severe Traumatic Brain Injury in South America: The Association Between Resources and Outcomes
Thesis (Master's)--University of Washington, 2013The burden of death and disability due to traumatic brain injury is increasing in low and middle income countries. The optimal management strategies and utilization of medical resources in resource limited settings are unknown. This multinational prospective observational study evaluated the association between resources and outcomes from severe TBI in South America. 203 patients with severe TBI were treated in a designated high or low resource setting, reflecting variation in ICP monitoring technology. There were significant differences in prehospital transport, ICU admission, and use of ICP monitoring between study groups that may impact outcomes. Patients treated in a high resource setting had significant improvements in functional outcome, but not mortality, at 6 months post-injury. Multivariate regression models showed that resource setting, independent of ICP monitoring, predicted functional outcome at 6 months after severe TBI. Understanding the characteristics that explain this variation and guiding appropriate resource allocation may improve outcomes
Religion on Campus: Suggestions for Cooperation between Student Affairs and Campus-Based Religious Organizations
Prevalence of Comorbidity and its Association with Traumatic Brain Injury and Outcomes in Older Adults
Achtergronden en toepassingen van de relatie van Th. De Donder
Achtergronden en toepassingen van de De Donder-relatie LN(v/v)=A/RT worden weergegeven in deze studie. Aangetoond wordt dat reakties geen gebruik maken van de mogelijkheid van thermodynamische koppeling, maar via kinetische koppeling affiniteitsproblemen overwinnen. Met behulp van de kinetiekbeschrijving van M.I. Temkin voor complexe reakties kan inzicht worden verkregen in reaktiemechanismen. Via het principe van Sabatier en De Donder kan worden aangetoond dat bezettingsgraden, affiniteitniveau's en adsorptiewarmten van reaktie-intermediairen een zeer belangrijke rol spelen in de katalyse om thermodynamisch ongunstig gelegen reaktiestappen te laten verlopen. Het principe van De Donder blijkt een krachtig hulpmiddel om affiniteit en reaktiesnelheid te koppelen en zo inzicht te verwerven in de werking van reaktiemechanismen. x A = affiniteit ṽ, ṽ = heen- en teruggaande reaktiesnelheidApplied SciencesAnorganische en Fysische Chemi
Testing of electron beam irradiated sheep wool for adsorption of Cr(III) and Co(II) of higher concentrations
Electron beam irradiated sheep wool dosed (0–410) kGy showing good adsorption properties was tested for Cr(III) and Co(II) of higher concentrations. Fitting to ten isotherm models was examined as follows: Langmuir, Freundlich, Dubinin-Radushkevich, Temkin, Flory-Huggins, Halsey, Harkins-Jura, Jovanovic, Elovich and Redlich-Peterson. Both cations being Lewis acids generate complex salts, such as carboxylates or cysteinates, with ligands from keratin. Various composition and architecture of the complexes are responsible for different isotherm model fitting. The chromic cation showed adherence to Freundlich, Temkin, Halsey, Harkins-Jura and Jovanovic models for all or almost all dosed samples unlike cobaltous cation matching Langmuir, Flory-Huggins and Redlich-Peterson isotherm models. No model fitted the both examined cations simultaneously. On the contrary, simultaneously non-fitting to all dosed samples was observed for Elovich and partially Dubinin-Radushkevich models. © 2021 The Author(s)Univerzita Palackého v Olomouc
A Manual for the Glasgow Outcome Scale-Extended Interview
The Glasgow Outcome Scale-Extended (GOSE) has become one of the most widely used outcome instruments to assess global disability and recovery after traumatic brain injury. Achieving consistency in the application of the assessment remains a challenge, particularly in multi-center studies involving many assessors. We present a manual for the GOSE interview that is designed to support both single- and multi-center studies and promote inter-rater agreement. Many patients fall clearly into a particular category; however, patients may have outcomes that are on the borderline between adjacent categories, and cases can present other challenges for assessment. The Manual includes the general principles of assessment, advice on administering each section of the GOSE interview, and guidance on “borderline” and “difficult” cases. Finally, we discuss the properties of the GOSE, including strengths and limitations, and outline recommendations for assessor training, accreditation, and monitoring
J Pain
PerspectiveThis is the first study to examine the prevalence of persistent pain over long-term follow-up in adolescents after TBI and its impact on health-related quality of life. These findings indicate that adolescents with TBI may benefit from timely evaluation and intervention to minimize the development and impact of pain.R49 CE001021/CE/NCIPC CDC HHSUnited States/K24 HD060068/HD/NICHD NIH HHSUnited States/R49 CE 001021/CE/NCIPC CDC HHSUnited States/T32 GM086270/GM/NIGMS NIH HHSUnited States/K24HD060068/HD/NICHD NIH HHSUnited States/5T32GM086270-03/GM/NIGMS NIH HHSUnited States
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