83 research outputs found

    The Crying Tree: Conversation about Transformative Forgiveness

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    Naseem Rakha, author of The Crying Tree, speaks at Humboldt State University on November 6, 2009. Part of the 2009 annual Campus Dialogue on Race

    Rare but There: Ceftriaxone-Induced Neutropenia in a Patient With a Brain Abscess.

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    © Copyright 2024 Naseem et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.This case report details the case of a 70-year-old man with Marfan syndrome and hypertension who developed neutropenia after an eight-week course of ceftriaxone, used to treat a brain abscess. Initially presenting with tonic-clonic seizures and headaches, his condition was managed with ceftriaxone and metronidazole. The subsequent drop in neutrophil counts from 7.54 × 10^9/L to 0.87 × 10^9/L leads to the discontinuation of ceftriaxone and the administration of granulocyte-colony stimulating factor (G-CSF), which effectively restored the neutrophil levels. This case highlights that clinicians should be aware of ceftriaxone-induced neutropenia as a potential complication, especially in patients undergoing prolonged therapy. Regular monitoring and timely management are essential for patient safety and favorable outcomes

    Fabry-Perot studies of the Milky Way bar: kinematics, chemical composition and instrumentation

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    Galactic bars and bulges play an important role in the formation and evolution processes in disk galaxies. There is now substantial evidence that our Galaxy is barred, and many unresolved questions about the structure, dynamics and star formation history of the inner Galaxy remain. We use Fabry-Perot (FP) absorption line imaging spectroscopy to measure radial velocities using the CaII8542 line in 3360 stars towards three lines of sight in the Milky Way's bar: Baade's Window and offset positions at (l,b) ~ (pm 5.0, -3.5). This sample includes 2488 bar red clump giants, 339 bar M-giants, and 318 disk main sequence stars. We measure the first four moments of the stellar velocity distribution of the red clump giants, and find it to be symmetric and flat-topped. We detect stellar streams at the near and far side of the bar with velocity difference ~ 30 km/s at l = +/- 5, indicating strong non-circular motions. We do not detect two separate streams in Baade's Window. Our M-giants kinematics agree well with previous studies, but have dispersions systematically lower than those of the red clump giants by ~10 km/s. We show that reliable absorption line strengths can also be measured using FP spectroscopy. The CaII8542 line is a good indicator of metallicity and its calibration to [Fe/H] is determined for globular cluster red giants in previous investigations. We derive such a calibration for the bulge giants and use it to infer metallicities for our red clump sample. We present the stellar metallicity distributions along the major axis of the bar. We find the mean [Fe/H] in Baade's Window close to solar, and the distribution in this field agrees well with previous works. We find negative gradients in the mean metallicity and its dispersion along the bar. We detect a signature of a possible new tidal stream at l = +5.5, in both our velocity and metallicity distributions. We also measure the metallicity of a bulge globular cluster NGC 6522 in our Baade's Window field to be -0.9 dex, in good agreement with previous high-resolution spectroscopic measurements, demonstrating the reliability of our metallicity measurements. We also present the design and testing of the FP system for the 10-meter class Southern African Large Telescope, and its characterization as measured in the laboratory. It provides spectroscopic imaging at any desired wavelength spanning a bandpass 430 -- 860 nm, at four different spectral resolving powers ranging from 300 to 9000. This FP system will provide a powerful tool for imaging spectroscopy on one of the world's largest telescopes.Ph.D.Includes bibliographical referencesby Naseem Rangwal

    A variational framework for multi-scale defect modeling in strained electronics and processing of composite materials

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    With the recent advances in material processing technologies and the introduction of the material genome initiative, material processing has gained an increased level of attention in the research community. Primary challenges in most material processing technologies and specifically in composite materials are the uncertainties concerning the material’s performance under loading whether it be static, dynamic or cyclic. That is due to the variabilities in these technologies that may lead to the formation of defects within the material parts at critical location during processing. This dissertation presents a deterministic defect modeling framework based on a system of variationally consistent formulations that allow for the modeling of the material processing stage and incorporate multi-physics coupling for multi-constituent materials. A stabilized and novel discontinuity capturing formulation is developed to model multi-phase flow of the materials and their defect while sharply capturing the jumps in material properties, material compressibility and kinetic reaction across the multi-phase interfaces. The method is based on employing structured non-moving meshes to solve the Navier-Stokes equations employing a finite element method (FEM) stabilized via the Variational Multiscale Method (VMS). Within VMS framework a discontinuity capturing method is derived that allows for sharp discontinuity capturing of the physical discontinuities of across phases within a single numerical element allowing for highly accurate and discrete representation of the interfacial physical phenomena. In addition, surface tension is incorporated into the formulation to discretely model jumps in the pressure field. The multi-phase interface is evolved employing a stabilized level-set method allowing for intricate motion of the two phases and the discontinuities within the Eulerian mesh. The formulation is then expanded to incorporate discontinuities in the governing system of equations allowing for modeling adjacent compressible-incompressible fluids within a unified formulation. Coupled with the thermal evolution within the constituents of the material and accounting for phase change and mass leading to mass transfer across the interface the materials, kinetic evolution of the material viscosities is modeled at the material points accounting for variability in the flow behavior as a function of kinetic curing. Finally, a previously developed isogeometric FEM method is expanded to model quantum defect evolution of strained electronics and the effect of straining on the electronic properties of these materials. Representative numerical tests involving complex multi-phase flows of physical instabilities, hydrodynamic collapse of bubbles and convective mass transfer along with electronic band-gap structures with strain effects are presented as validations and applications for the framework’s robustness. Finally, the chemo-thermo-mechanical coupling and real-life application is presented via a fully coupled problem involving processing of a composite bracket during the early curing stages.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2020-12-01The student, Ahmad Al-naseem, accepted the attached license on 2018-12-05 at 18:19.The student, Ahmad Al-naseem, submitted this Dissertation for approval on 2018-12-05 at 18:31.This Dissertation was approved for publication on 2018-12-07 at 08:12.DSpace SAF Submission Ingestion Package generated from Vireo submission #13227 on 2019-02-08 at 11:41:22Made available in DSpace on 2019-02-08T18:44:40Z (GMT). No. of bitstreams: 2 AL-NASEEM-DISSERTATION-2018.pdf: 18855374 bytes, checksum: 67868cf8f43848be73dca535f0f76023 (MD5) LICENSE.txt: 4211 bytes, checksum: ae9f11b64542d54e164556ef305a60cd (MD5) Previous issue date: 2018-12-07Embargo set by: Seth Robbins for item 109972 Lift date: 2021-02-08T18:44:50Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 109972 on 2021-02-09T10:15:45Z

    Geopolitical Value of Gwader for the Region (Mainly for Pakistan, China and the Region)

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    In the present geo-economics situation, the significance of the sea ports cannot be ignored; Because of the important sea ports, Dubai is now the nucleus of the world‟s economy, especially of the Gulf. But as things are, the Middle Eastern part has been engulfed, a lot lately, in serious political conflicts because of which large disturbances are being predicted in the next few years. In order to deal with this situation, an alternative, near to Dubai, needs to be positioned very soon so that uninterrupted and a constant supply of oil is ensured from Gulf region throughout the world, even in case of a worst political scenario. The port in Karachi could have been a better option but the load on that port is to such an extent that it cannot bear much more. The port of Gwader is not only in the vital interest of Pakistan and China but also in the paramount interest of the region‟s development. Thus the vital importance of Gwader cannot be ignored for the region especially for China and Central Asi

    Investigating Urinary Pathogens and Their Antibiotic Resistance: A Cross-Sectional Urine Culture Study.

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    © Copyright 2024 Khan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Introduction: Urinary tract infections (UTIs) are among the most prevalent infectious diseases. Females are more affected than males. The primary culprit is Escherichia coli. Multiple research investigations have documented widespread antimicrobial resistance in uropathogens, sparking global concerns, especially regarding the rise of multidrug resistance (MDR). Methodology: This cross-sectional study was conducted from December 2023 to March 2024. A non-probability purposive sampling technique was employed to select participants, and informed consent was obtained from them. Data were extracted from the culture and sensitivity reports of these patients. The collected data were meticulously entered into IBM SPSS Statistics for Windows, Version 21 (IBM Corp., Armonk, NY). The findings were then presented using a blend of percentages and numerical figures, offering a clear and concise representation of the data. Results: Our study of 313 participants showed a higher prevalence of UTIs in females (219, 70%) compared to males (94, 30%). E. coli and Citrobacter were the predominant pathogens, with E. coli and Citrobacter more common in females, while Enterobacter and Staphylococcus were more prevalent in males. Antibiogram analysis revealed sensitivities to specific drugs like nitrofurantoin and meropenem, while resistance was observed against others, including polymyxin B and ampicillin. These findings stress the need for tailored UTI treatment approaches. Conclusions: In conclusion, our research highlights a concerning trend of escalating antibiotic resistance among Pakistani patients with UTIs. Tobramycin B, ticarcillin-clavulanic acid, ampicillin, and clotrimazole exhibited the highest resistance rates, while imipenem, meropenem, nitrofurantoin, sulfonamides, and tigecycline demonstrated notable sensitivity. These findings emphasize the urgent need for the exploration of alternative treatment options to combat rising resistance levels effectively

    Development of a universal cryogenic test facility

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    Magnets for High Energy Physics applications built to date are generally superconducting magnets, which operate at cryogenic temperatures. The reliability and safety of the applications are entirely dependent on good design which in turn rely heavily on predictable materials performance. Where at these low temperatures the fracture toughness is of importance to be known (alongside mechanical properties such yield and tensile strength). At CERN at the materials and engineering department (EN-MME-MA) a testing facility is being commissioned for the measurement of mechanical at cryogenic temperatures. A tensile test facility has been realised, yet no such set-up is available for fracture toughness measurement. The aim of this thesis was to develop a test set-up for the measurement of the fracture toughness in order to realise a universal cryogenic testing system, which can be used for both tensile tests and fracture toughness test at low temperatures. A design for a set-up is proposed for the measurement of the fracture toughness which can be employed within the current cryostat. The design of the tooling and cryostat have been extensively verified using numerical methods taking into account thermal effects (such as conduction and contraction) and the varying material properties at these low temperatures. A modified C(T) specimen is proposed for more robust and reliable set-up. For this modified specimen it is shown with numerical methods that the modification are expected to have a negligible impact on the fracture toughness measurements. Tests have been performed using the proposed design with four specimen fabricated from two different materials (SS316L and Ti6Al4V), at both room temperature and at 4 K (using liquid helium). The set-up is shown to provide sufficient data for the characterisation of the fracture toughness for both Linear Elastic Fracture Mechanics tests as well as Elastic Plastic Fracture mechanics tests.Mechanical Engineerin

    Efficacy of Supports Available to Marginalised Sexual Minority Youth Through an Attachment Theoretical Lens

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    The prevalence of homeless youth in Canada has been increasing with over 30,000 youth homeless, and Indigenous and sexual- and gender-minority youth being overrepresented. A disparity exists amongst marginalised sexual-minority youth (MSMY) who experience bullying, victimisation, mental health challenges, and homelessness disproportionately to their cis gendered peers. The author drew on existing literature to examine the unique needs of MSMY who are street involved, homeless, and/or transient and the efficacy of available community supports through an attachment theoretical lens. Common themes that the author synthesised from the literature are levels of victimisation, prevalence of relational and social trauma, cultural needs, and protective factors of sexual-minority youth (SMY). The findings suggest that systemic discrimination (i.e., sexism, racism), organisational systems (i.e., school systems, governments), adverse childhood experiences (ACEs) and relational trauma, and the lack of natural supports are associated with poor outcomes for MSMY. However, accessibility to resources, communities' acceptance, collaboration amongst professionals, and therapeutic tools such as affirmative cognitive behavioural therapy (CBT) and mindfulness interventions are associated with positive health outcomes. The literature review reveals a gap in research on MSMY in Canada, and further research in this area is warranted. Lastly, the author makes recommendations based on empirical findings and suggestions for future research

    Correction to: Sars-Cov-2 Infection in People with Type 1 Diabetes and Hospital Admission: An Analysis of Risk Factors for England

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    The article “Sars-Cov-2 Infection in People with Type 1 Diabetes and Hospital Admission: An Analysis of Risk Factors for England”, written by Adrian H. Heald, David A. Jenkins, Richard Williams, Rajshekhar N. Mudaliar, Amber Khan, Akheel Syed, Naveed Sattar, Kamlesh Khunti, Asma Naseem, Kelly A. Bowden-Davies, J. Martin Gibson, William Ollier, on behalf of the CVD-COVID-UK/COVID-IMPACT Consortium was originally published electronically on the publisher’s Internet portal (currently SpringerLink) on August 25, 2023, without open access. Now, the article is updated with open access as This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The original article has been corrected
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