906 research outputs found

    Fakta Sejarah Kekalahan Jepang dalam Perang Dunia II pada film Nihon no Ichiban Nagai Hi Karya Sutradara Masato Harada

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    Film Nihon no Ichiban Nagai Hi merupakan salah satu film bertema sejarah karya sutradara Masato Harada. Film ini berpusat pada bulan Agustus 1945, di mana selama akhir Perang Dunia II Jepang didesak untuk menerima Deklarasi Potsdam dan Amerika Serikat menjatuhkan bom atom di Hiroshima dan Nagasaki. Dalam film ini terdapat beberapa fakta sejarah yang bisa menambah wawasan mengenai sejarah Jepang khususnya mengenai kekalahan Jepang dalam Perang Dunia II. Penelitian ini bertujuan untuk mendeskripsikan fakta sejarah kekalahan Jepang dalam Perang Dunia II pada film Nihon no Ichiban Nagai Hi karya sutradara Masato Harada dengan menggunakan pendekatan historis dan metode deskriptif analisis untuk menganalisis kejadian tersebut dengan fakta-fakta yang ada dan memperkuat bukti bahwa kejadian tersebut benar-benar terjadi. Hasil penelitian menunjukkan bahwa kekalahan Jepang dalam Perang Dunia II disebabkan oleh desakan pihak Sekutu yang meminta Jepang menyerah tanpa syarat dengan mengeluarkan Deklarasi Potsdam. Namun, Jepang yang memilih menunjukkan sikap diam ini diartikan Sekutu bahwa Jepang tidak menerima Deklarasi Potsdam hingga kemudian pihak Amerika yang geram menjatuhkan bom atom di Hiroshima dan Nagasaki serta disusul dengan pernyataan perang oleh Uni Soviet kepada Jepang yang membuat Jepang semakin tersudut. Kabinet Jepang menemui hasil buntu dalam pertemuannya membahas pengambilan keputusan Deklarasi Potsdam sehingga Perdana Menteri Kantaro Suzuki meminta Kaisar Hirohito untuk memberikan tanggapannya, Kaisar Hirohito dengan lugas menyatakan keputusannya bahwa dengan menerima Deklarasi Potsdam akan dapat menghentikan perang dan menghindarkan Jepang dari penderitaan dan kehancuran. Pada 14 Agustus 1945 Jepang menyerah kepada Sekutu dan keesokan harinya melalui siaran radio nasional disiarkan rekaman suara Kaisar Hirohito membacakan Maklumat Kaisar yang menyatakan bahwa perang telah berakhir

    Correction to: Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan

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    The article Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan, written by Mitsuhiko Nose, Momoka Tada, Rika Kojima, Kumiko Nagata, Shinsuke Hisaka, Sayaka Masada, Masato Homma and Takashi Hakamatsuka, was originally published Online First without open access. After publication in volume 71, issue 4, page 711–722 the author decided to opt for Open Choice and to make the article an open access publication. Therefore, the copyright of the article has been changed to © The Author(s) 2018 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</jats:p

    “Masato de Yuca” and “Chicha de Siete Semillas” Two Traditional Vegetable Fermented Beverages from Peru as Source for the Isolation of Potential Probiotic Bacteria

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    Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This research was funded by the Ibero-American Programme on Science and Technology for Development (CYTED), grant number 917PTE0537. The Spanish team was funded by the “Agencia Estatal de Investigación” and the “Fondo Europeo de Desarrollo Regional” (AEI/FEDER, UE), grant number PCIN2017-075″. The Peruvian team was funded by the National Council of Science and Technology and Innovation of Peru through its execution unit National Fund for Scientific, Technological and Technological Innovation (CONCYTEC/FONDECYT), grant No. 001–2017.In this work, two Peruvian beverages “Masato de Yuca,” typical of the Amazonian communities made from cassava (Manihot esculenta), and “Chicha de Siete Semillas,” made from different cereal, pseudo-cereal, and legume flours, were explored for the isolation of lactic acid bacteria after obtaining the permission of local authorities following Nagoya protocol. From an initial number of 33 isolates, 16 strains with different RAPD- and REP-PCR genetic profiles were obtained. In Chicha, all strains were Lactiplantibacillus plantarum (formerly Lactobacillus plantarum), whereas in Masato, in addition to this species, Limosilactobacillus fermentum (formerly Lactobacillus fermentum), Pediococcus acidilactici, and Weissella confusa were also identified. Correlation analysis carried out with their carbohydrate fermentation patterns and enzymatic profiles allowed a clustering of the lactobacilli separated from the other genera. Finally, the 16 strains were submitted to a static in vitro digestion (INFOGEST model) that simulated the gastrointestinal transit. Besides, their ability to adhere to the human epithelial intestinal cell line HT29 was also determined. Following both procedures, the best probiotic candidate was Lac. plantarum Ch13, a robust strain able to better face the challenging conditions of the gastrointestinal tract and showing higher adhesion ability to the intestinal epithelium in comparison with the commercial probiotic strain 299v. In order to characterize its benefit for human health, this Ch13 strain will be deeply studied in further works. © 2021, The Author(s).Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concyte

    Financing small and medium sized enterprises for sustainable development : a view from the Asia-Pacific region

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    Macroeconomic Policy and Development Division, working paper series.This discussion paper was prepared for ESCAP by Nick Freeman, Independent Economic Development Consultant. The author gratefully acknowledges the contributions made by Masato Abe, Sailendra Narain, Michael Troilo and J. S. Juneja

    Environmental Violence in Minamata: Responsibility, Resistance, and Religiosity in the Case of Ogata Masato and Hongan no Kai

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    The small town of Minamata is infamous for the industrial disease named after the city. This disease resulted from having ingested methyl mercury, a substance released for more than three decades by a factory owned by the Chisso Corporation. Upon entering the human body, mercury affects the nervous system, resulting in paralysis, and often leading to a slow death. Examining how such violence was inflicted on human beings and on the environment involves a complex array of economic, environmental, and sociocultural issues, all revolving around the notions of justice and responsibility. This article analyzes the local residents&rsquo; responses to the irreparable damage done to them, focusing in particular on the thoughts and actions put forward by Ogata Masato and a group called Hongan no kai, who chose to carve bodhisattva statues. Investigating the victims&rsquo; religiosity, the author argues that the praxis put forward by the Minamata people resonates with the perspective articulated by Italian philosopher Giorgio Agamben. After having witnessed how justice had been exhausted and their case had been lost in the Japanese legal system, the victims showed their resilience in coming up with original responses, which also offer valuable insight into current discussions centered on environmental ethics

    Introduction to almost o-minimality (Model theoretic aspects of the notion of independence and dimension)

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    This paper is a brief survey on an almost o-minimal structure, which was proposed by the author. A locally o-minimal expansion of the set of reals has strong properties which are not possessed by other locally a-minimal structures. An almost o-minimal structure is a promising generalization of a locally o-minimal expansion of the set of reals. It is always an expansion of an o-minimal structure and admits uniform local definable cell decomposition

    Expression of protease activating receptor-2 (PAR-2) is positively correlated with the recurrence of non-muscle invasive bladder cancer: an immunohistochemical analysis

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    Kozue Nakahara,1 Koji Yamasaki,1 Takahiro Nagai,1 Masato Fujii,1 Takahiro Akioka,1 Hiroki Takamori,1 Naoki Terada,1 Shoichiro Mukai,1 Yuichiro Sato,2 Toshiyuki Kamoto11Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan; 2Section of Diagnostic Pathology, Faculty of Medicine, University of Miyazaki, Miyazaki, JapanBackground: Matriptase, which is a Type II transmembrane serine protease,&nbsp;has the potential to activate several growth factors, including pro-hepatocyte growth factor (HGF). A G protein-coupled transmembrane cell-surface receptor and a protease-activated receptor 2 (PAR-2) are also required for activation by matriptase. Activation of PAR-2 has been reported to induce the progression of various cancers. In a previous study, we evaluated the correlation between upregulation of MET phosphorylation with high matriptase expression and worse prognosis in patients with muscle invasive bladder cancer; however, expression of PAR-2, matriptase and MET in non-muscle invasive bladder cancer (NMIBC) has not been evaluated.Materials and methods: We retrospectively analyzed the expression of PAR-2, matriptase and MET using 55 paraffin-embedded specimens obtained from patients with NMIBC by immunohistochemistry.Results: MET was significantly expressed in high-grade urothelial carcinoma (UC) and pathological T1 cancers. High expression of PAR-2 was significantly associated with a worse recurrence rate in NMIBC. In subgroup analysis, the expression of PAR-2 was also correlated with high recurrence rate in low-grade UC. In addition, expression of matriptase tended to correlate with worse recurrence rate in high-grade UC.Conclusion: Increased expression of PAR-2 was significantly correlated with worse recurrence rate in patients with NMIBC. In addition, expression of matriptase also indicated a tendency toward recurrence in high-grade UC, suggesting an important role of matriptase-induced PAR-2 activation in NMIBC.Keywords: PAR-2, matriptase, MET, NMIB
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