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Higher specificity in the serodiagnosis of leprosy by combined titration of antiphenolic glycolipid-I and antiphospholipid antibodies.
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The speckled immunofluorescence of epidermal nuclei as an in vivo phenomenon
No full textThe deposition of speckled-patterned immunoglobulins in epidermal nuclei has been investigated in seventeen patients with various diseases other than mixed connective tissue disease. The phenomenon was seen not only with low titres of circulating antinuclear antibodies of IgG and IgM classes, but even in their absence. The clinical significance of this finding remains obscure, but the common explanation, that it is a simple artifact, seems quite untenable
Identification of sequence similarities between Mycobacterium leprae and the myelin proteolipid protein by computational analysis.
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Ofuji's disease: high circulating titers of IgG and IgM directed to basal cell cytoplasm
No full textA patient with Ofuji's eosinophilic pustulosis and peculiar immunofluorescence findings is described. High titers of circulating IgG and IgM have been found directed to the cytoplasm of the basal cells of epidermis and the outer sheath of hair follicles. Such antibodies appear to be related to the course of the disease
Immunofluorescence findings in haematoporphyrin-induced keloid
No full textA case of haematoporphyrin-induced keloid is described in which immunofluorescence (IF) revealed antibodies eluted from circulating lymphoid cells directed against fibroblasts. The antibodies eluted belonged to the main Ig classes IgD and IgM and they did not bind complement in vitro. Their possible activity in stimulating fibroblasts is discussed
beta2-Glycoprotein I-dependent anticardiolipin antibodies as risk factor for reactions in borderline leprosy patients.
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