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Ghrelin in the gastroenteric tract of birds: immunoreactivity expression
No full textIn this study we have clearly demonstrated that ghrelin producing cells exist in the
chicken gastrointestinal tract. The distribution pattern and morphological character-
istics of ghrelin-ic suggest that they correspond to endocrine type cells. However,
further investigations are required in order to identify the specific cell types according
to the current classification (Solcia et al., 2000). In the frog stomach ghrelin endocrine
cells have been observed in the mucosa and in pit-associated glands (Galas et al.,
2002). In the rat and human stomach ghrelin-producing endocrine cells have been
identified as X/A like cells of the oxyntic mucosa (Kojima et al., 1999; Date et al.,
2000). These results indicate that chicken ghrelin is also evolutionally conserved both
in its distribution and in its aminoacidic sequence
Immunohistochemical study of orexins and leptin presence and distribution in the gastroenteric tract of stomachless and stomach-containing teleost
No full textImmunohistochemical study of orexins and leptin presence and distribution in the gastroenteric tract of non mammalian vertebrates
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Immunocytochemical detection of leptin-like immunoreactivity in the chicken gastroenteric tract.
No full textAbstract
Leptin is a hormone produced and secreted mainly by adipocytes, but also by other tissues such as placenta, brain, mammary, and pituitary glands. The gastric epithelium has also been reported as a source of leptin in mammals. In this study we examined the presence of leptin in the chicken gastroenteric tract by immunohistochemistry and Western blotting. Strong and widespread leptin-like immunoreactivity was observed in the mucosal epithelium of proventriculus plicae and in the epithelium of the complex compound glands. Numerous leptinimmunoreactive
cells were found along lining epithelium of duodenum villi, while few leptin-immunoreactive cells were observed in the basal
zone of duodenum glands. Many leptin-immunoreactive cells were found in the caeca at the basal zone of glands, while very few leptinimmunoreactive cells were found in the deep glandular structures of the large intestine. In the homogenates of chicken gastroenteric tract the protein detected using a human leptin-specific antibody had estimated molecular weight of approximately 15–16 kDa.
To our knowledge, this is the first report demonstrating leptin-like protein distribution in the whole gastroenteric tract of bird. This
finding constitute important data for the further understanding of the mechanism that regulate feeding behaviour in birds, farm animal for which the control of food intake and fatness are a high economic interest
Immunohistochemical presence of orexins in the gastroenteric tract of non mammalian vertebrates
No full textNeurotrofine e recettori TrK nel rene di pesci, anfibi e rettili: studio immunoistochimico
No full textDistribuzione di cellule immunoreattive alla grelinanel tratto gastroenterico di due specie di Teleostei.
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Studio immunoistochimico sulla localizzazione di peptidi coinvolti nel controllo dell’assunzione di cibo nel tratto gastroenterico dei teleostei.
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