85 research outputs found

    The Arab Avant-Garde: Musical Innovation in the Middle East

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    In the early nineteenth century, the term “avant-garde” began to capture greater semantic territory. Once purely a military phrase used to distinguish crack troops, it then assumed a high-ranking position within cultural expression, marking out art work that forged ahead and broke new ground. What can it mean to conjoin this French phrase with the word “Arab”? French forces, along with other imperial intruders, are no strangers to Arab terrain. The colonisation of Algeria, Tunisia, Morocco and Greater Syria followed in the wake of the brief Napoleonic “mission” to Egypt between 1798 and 1801. It was during this military foray that some of modern Europe’s most expansive data on Egyptian music was collected, information that comprised two whole volumes of Guillaume André Villoteau’s Description de l’Egypte. The Napoleonic campaign gathered not only military, but also cultural intelligence, if the two can be so easily separated

    SYNTHESIS, MOLECULAR DOCKING AND ANTIBACTERIAL EVALUATION OF SOME NOVEL N-4 PIPERIDINYL DERIVATIVES OF SPARFLOXACIN

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    Objective: The present study envisage a series of sparfloxacin derivatives were synthesized (Q1-Q10) with added derivatives such as aminomethyl benzenesulfenyl, methyl (methylamino)benzenesulfenyl, amino methyl benzoyl chloride, nitromethyl benzoyl chloride, dimethyl phenylamino, methoxymethyl phenylamino, dimethyl oxopyrazol, methyl dioxopyrrolidine, methyl oxopyrrolidine, and N-Boc amino methyl methylpyrrolidine through N-Piperzinyl linkage.Methods: All the newly synthesized compounds were characterized by infrared,1H nuclear magnetic resonance, mass spectrometry, and elemental analysis technique, screened for docking stimulation to find out binding modes of synthesized derivatives with 3FV5 and 3IMW, and evaluated for in vitro antimicrobial activity.Results: From this study, it was found that the compound Q5 showed good antibacterial activity against Gram-positive (Staphylococcus aureus) and compound Q4 showed good antibacterial activity against Gram-negative (Escherichia coli) in comparison with standard drugs (ciprofloxacin and sparfloxacin). The zone of inhibition and minimum inhibitory concentrations studies performed to synthesized compounds. The correlation between experimental data (minimum inhibitory concentrations) and docking score suggests that penetration for docking simulation is good to mild in reproducing experimental orientation of these synthesized compounds.Conclusion: The analogs of sparfloxacin are suggested to be potent inhibitors with sufficient scope for further exploration

    Synthesis and Characterization of N-(3-(8-Bromoimidazo[1, 2-a] pyridin-2-yl)-4-Fluorophenyl)Benzamide Derivatives

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    We report here the synthesis and characterization of new N-(3-(8-bromoimidazo[1, 2-a]pyridin-2-yl)-4-fluorophenyl)benzamide derivatives. This collection was obtained from 3-(8-bromoimidazo [1,2-a]pyridin-2-yl)-4-fluoroaniline(5). The family of new compounds was characterized by 1H-NMR, 13C-NMR, FT-IR and LC-MS analysis.</jats:p

    6-Chloro-N-(pyridin-4-ylmethyl)pyridine-3-sulfonamide

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    In the title sulfonamide derivative, C11H10ClN3O2S, the dihedral angle between the pyridine rings is 46.85&#8197;(12)&#176;. The N atom of the chloropyridine ring is anti to the N&#8212;H bond. In the crystal, molecules are linked through N&#8212;H...N hydrogen bonds into zigzag chains parallel to [001] with a C(7) graph-set motif

    Estimation of Stress Strength Reliability for Transmuted Exponentiated Inverse Rayleigh Distribution

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    The problem of estimation of reliability of systems in stress-strength set up is an important area of research in Statistics, particularly, in Statistical Inference on reliability. In this paper, the estimation of stress-strength reliability when the strength and stress variables are assumed to be independently distributed as transmuted exponentiated inverse Rayleigh distribution (TEIRD) is considered. The TEIRD is a general distribution which includes transmuted inverse Rayleigh distribution, exponentiated inverse Rayleigh distribution and inverse Rayleigh distribution as a particular cases. The maximum likelihood estimator of stress -strength model is derived. Also, asymptotic confidence interval for reliability is constructed. The real data analysis is considered and the simulation study is conducted

    IMPACT OF CHANGE ORDERS ON THE COST PERFORMANCE OF MASS TIMBER CONSTRUCTION PROJECTS

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    Thesis (M.S.)--Michigan State University. Construction Management - Master of Science, 2024One of the major barriers to the widespread adoption of mass timber as a material is lack of knowledge. This lack of knowledge further promotes issues like high production and construction costs. The construction industry in the United States has been reluctant to accept mass timber as a new technology owing to these higher initial costs. Consequently, the most critical factor affecting the selection of a construction material is its cost performance. A successful construction project is governed by its cost performance. Although, the cost performance of a project can be affected by cost overruns and change orders. These project costs can be optimized by reducing the time. Owing to its prefabricated nature, mass timber construction can cut down time. While change orders negatively affect the time of a project, there is a need to understand their impact on mass timber construction. This study analyzes the impact of change orders on the cost performance of mass timber construction projects. The expected deliverables are to quantify and understand the most common causes of change orders in mass timber projects. The researcher believes that this study is a steppingstone toward the widespread adoption of mass timber as a construction material. Project data was collected for 34 projects from General Contractors around the country. Pearson\u2019s correlation, descriptive statistics, and ANOVAs were used to analyze the data collected. This study observed the relationship between the mass timber scope and the mass timber change orders. Along with that the project delivery methods and their impact on the construction costs was studied. The author believes a more widespread adoption of mass timber is beneficial through project team integration and reduction of change order costs.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references

    Review of Research on Public Libraries: A Scopus Based Bibliometric Analysis

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    Public libraries are considered as peoples universities and can play a vital role in overall development of community they serve with the help of the resources and services. We have collected to data from the Scopus database for the period of 1971-2019. We have identified the trends in public libraries research, prominent authors who are involved in the research on public libraries issues and Y applied to evaluate the author’s contribution. Core journals and productive countries also determined and taken up the author supplied keyword analysis over decades. This work would be useful to the researchers who are working on the public libraries

    Bed blockers: A study on the elderly patients in a teaching hospital in India

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    A cross-sectional study of in-patients over the age of 60 years was conducted at district McGann Hospital, Shimoga on patients who were classified as bed blockers. Level of dependency and cognitive function of these patients were assessed using Barthel scale and Abbreviated mental test (AMT) respectively. Median age of the study population was 67 years; majority of them were men. Most of them were admitted in the medical ward and the median time to be labeled as bed blocker was 32 days. These bed blockers were a weak group of patients with an average 3.1 pathology per case. Majority of them suffered from neurological disorders and cardiovascular disease. High level of dependence was noted with a mean Barthel score of 29.68 (Range 0 -100). Low levels of cognitive function was also noted among these patients with a mean AMT of 4.76 (Range 0 -10).These findings demonstrate that the bed blockers in McGann hospital suffer not only from genuine health problems but also have a high dependency level in activities of daily living which hamper their discharge to the community. Community based rehabilitation using an intersectoral approach may help at least the less dependent to return home
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