582 research outputs found

    Feste (e relaciones de fiesta) nella Sardegna del primo Settecento: "un delirio de exorbitante vanidad"

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    The relaciones de fiesta constitute a significant portion, over the past decades object of critical attention by scholars of various European and American universities, of that production generally identified as paraliterary, and therefore marginalized. The discovery and subsequent exploitation of these texts is based on the fact that they are real reservoirs from which elements of scientific interest from multiple perspectives can be drawn: for the historian of literature, culture, religious beliefs, popular traditions, history of art, of the editions etc. The essay in question analyzes the Sucinta descripcion de los regozijos (perhaps of Ignacio Paliacho, author of the loa included in the text), published in Cagliari in 1722 for the wedding of Prince Carlo Emanuele. Preliminarily, thanks to investigations conducted in the Archives of State and the Town Council of Cagliari, data relative to the typology of the feasts and of the occasions which determined them, are provided, contributing,in this way, to the positioning of such materials of local origin, in the wider context mentioned above

    Marginalidad social y aspiración de medro en las relaciones de sucesos: el caso de "El hijo del verdugo"

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    Analysis of the news pamphlet El hijo del verdugo highlights the continuation of the debate, even in popular literature, on a crucial issue, namely the desire for upward mobility by members of the lowest echelons of society. The presentation of the narrative in two parts allows the anonymous author to organise the rich and complex material into autonomous narrative units, as in traditional folk literature, and to link its multiple thematic features. Even though the title makes clear the qualities of the protagonist in his unstoppable quest to better himself, the happy ending comes about mainly thanks to his decision to keep the company of good people and to turn a series of coincidences to his advantage, in the same way as the heroes of picaresque novels do, thanks to expedients of dubious morality.El análisis de la relación El hijo del verdugo atestigua la perduración del debate, aun en la literatura popular y de consumo, sobre la cuestión de la aspiración de medro por parte de sujetos pertenecientes a las capas más humildes de la sociedad. El texto se distribuye en dos partes, cada una autónoma desde el punto de vista de la articulación y entrelazamiento de variados motivos temáticos. Si bien ya en el título se hace referencia a los méritos del protagonista, el hijo del verdugo, en su irrefrenable afán de medro, sin embargo su fortuna final parece más bien depender de su decisión de “arrimarse a los buenos” y de su capacidad como individuo de volver en su favor una serie de casualidades recorriendo, igual que los pícaros, a ardides e industrias de dudosa licitud moral

    BEYOND HBIM: SERIOUS GAMES AND PROCEDURAL MODELLING FOR HERITAGE DISSEMINATION

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    In the study of built heritage, the potential offered by the BIM methodology finds effective application in the knowledge and dissemination process. Today, the HBIM methodology often develops from 3D scanning point clouds with the so-called Scan-to-BIM processes. The complexity that often characterizes the architectural elements of the historical heritage and the lack of information on construction details and geometries, constitute a critical factor that sometimes affects the effectiveness of the application of the BIM methodology. Procedural methods define an approach that can help us when it is necessary to use external modelling tools for the local modelling of complex elements. Algorithmic modelling potentially could significantly reduce the investment normally required in digital content modelling operations, also in terms of time consuming. Furthermore, in procedural modelling, the definition of the detail can be calibrated a priori according to the objectives of the workflow. The research addresses the difficult management of point clouds in workflows aimed at the realization of the so-called serious games, tools that have proved invaluable in educational and teaching processes, as well as in the dissemination and promotion of heritage. Involving a remarkable variety of digital instruments for representation, serious games define a research topic in which the different needs related to the representation of the complexity of the objects can be investigated. Aimed at defining an effective development process for serious games, the paper proposes an HBIM workflow for reconstruction of 3D environments of historic buildings starting from laser scanning surveying approach

    Petits métiers du transport à Maroua (Cameroun)

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    Paba Salé Mahamat. Petits métiers du transport à Maroua (Cameroun). In: Cahiers d'outre-mer. N° 137 - 35e année, Janvier-mars 1982. pp. 77-85

    Newly Synthesized Compound, PABA-Ursodeoxycholic Acid, for Evaluation of Intestinal Bacteria

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    From the standpoint of utilizing a distinctive feature of para-aminobenzoic acid (PABA) and intestinal bile acid metabolism, a conjugate of ursodeoxycholic acid with PABA (PABA-UDCA) was newly synthesized for studying whether it can be a good material or not to evaluate enteric bacteria. In incubation experiment, this compound was reasonably deconjugated by cholylglycine hydrolase resulting in the release of PABA. In animal experiment, urinary excretions of PABA were determined during six hours following oral administration of 10 mg PABA-UDCA. Control rats (n=7) excreted 140.1 ± 59.5 μ,g (mean ± SD) of PABA. By contrast, the rats (n=9) with intestinal antisepsis by antibiotic administration excreted less (18.3 ± 16. 7 μg; P < 0.001) whereas those with intestinal bacterial overgrowth by making enteric blind loop excreted more (451.1 ± 223.6 μg; P < 0.01). These observations indicate that this new compound is likely to offer a simple and rapid method for evaluation of the intestinal microorganisms

    Integrated digital survey for the knowledge and enhancement of the IIWW heritage. The natural Park Molentargius-Saline (Cagliari, Italy)

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    The essay illustrates the choices aimed at building a digital database of military architectures made in Sardinia during the Second World War. It is a constructive stylistic repertoire characterized by an interesting historical-cultural and landscape value composed by more than 1.500 artifacts positioned along the coast of the island and designed to protect the major urban centers and areas of strategic interest. The small bunkers built adapting the precise models designed by the Italian and German Military Genius gave rise to an interesting repertoire. The need for mimesis in the landscape of these 'sentries' has in fact required an adaptation to the places of the typological solutions indicated in the archive documents. A possible recovery and enhancement of this heritage necessarily passes through an activity of knowledge and cataloging entrusted to integrated digital survey methods

    Photolysis and Cellular Toxicity of the Organic Ultraviolet Filter Chemical Octyl Dimethyl Para-Aminobenzoic Acid (OD-PABA) and its Photoproducts

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    Organic ultraviolet filter chemicals (UVFCs) are the active ingredients used in many sunscreens to protect the skin from UV light. These chemicals have been found in numerous aquatic environments, leading to concerns about how they might affect aquatic organisms and humans. UVFCs have also been known to penetrate the skin and act as endocrine-disrupting compounds. Many personal care products like lip balms and makeups contain the UVFC octyl dimethyl para-aminobenzoic acid (OD-PABA), also known as Padimate O. Upon exposure to UV light, OD-PABA degrades into numerous photoproducts. Some of these photoproducts have been previously identified, whereas others have not. Furthermore, the cellular toxicity of OD-PABA and its photoproducts are not well-established. In this study, we have isolated and characterized the major products of OD-PABA photolysis. We have also determined the cellular toxicities of OD-PABA and some of its isolated photoproducts to mammalian cells in vitro. It was found that OD-PABA is toxic to mammalian cells at micromolar concentrations, which are relevant to current human usage. Additionally, the OD-PABA complete photolysate was shown to exhibit higher toxicity than that of the parent compound itself; photoproduct IV had comparable toxicity to OD-PABA. As OD-PABA is a commonly used UVFC, results from this study provide us with an enhanced understanding of OD-PABA photolysis and its potential human and environmental health effects, which will allow us to better evaluate the suitability of this UVFC as a sunscreen agent

    The pab1 gene of Coprinus cinereus encodes a bifunctional protein for para-aminobenzoic acid (PABA) synthesis: implications for the evolution of fused PABA synthases

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    The pab1 gene of the basidiomycete Coprinus cinereus encodes PABA synthase, necessary for para-aminobenzoic acid production. The C. cinereus protein is bifunctional with an N-terminal glutamine amidotransferase domain and a C-terminal chorismate amination domain. In most bacteria, these two functions are encoded in separate genes (e.g., pabA and pabB of E coli). Fused PABA synthases have so far been detected in actinomycetes, Plasmodium falciparum, fungi and Arabidopsis thaliana. Phylogenetic analysis shows that the fused PAB sequences form a tight group that also includes uncharacterized PabB homologues from several bacteria. Unfused bacterial PabA proteins group with the glutamine amidotransferase subunits of bacterial anthranilate synthases, independent of organismal systematics, indicating a complex and perhaps independent evolutionary origin. In contrast, unfused PabB group and fused PabA/B proteins form a monophyletic group on a branch separate from the chorismate amination subunits of anthranilate synthases, probably reflecting a need for recognition of different positions in the common substrate chorismate

    Improved specificity of the PABA test with p-aminosalicylic acid (PAS)

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    Until now use of the PABA test together with [14C] PABA to calculate the PABA excretion index has probably been the best adaptation suggested to enhance the specificity of this non-invasive pancreatic function test. Drawbacks of the method are the application of radioactivity, the fact that children, pregnant women, and patients with renal insufficiency have to be excluded from the test, and the possible interference of drugs and isotopes. We propose simultaneous administration of p-aminosalicylic acid (PAS) in the PABA test and quantification of the urinary PABA and PAS excretion with liquid chromatography. Urinary PABA and PAS excretion in six hours are comparable (69.5 +/- 8.4% and 65.6 +/- 18.4% respectively in five healthy volunteers). Application of the PABA/PAS ratio was compared with the urinary PABA excretion in 21 normal controls, 38 patients with pancreatic disease, and 42 patients without pancreatic pathology. The PABA/PAS ratio and the per cent PABA excretion correlated very well in pancreatic patients: (PABA/PAS ratio) = 0.0149 (% PABA) + 0.052 (r = 0.902). Use of the PABA/PAS ratio enhanced the specificity of the test from 76 to 89
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