266 research outputs found
Helicobacter pylori: A foodborne pathogen?
No full textHelicobacter pylori (H. pylori) is an organism that is widespread in the human population and is sometimes responsible for some of the most common chronic clinical disorders of the upper gastrointestinal tract in humans, such as chronic-active gastritis, duodenal and gastric ulcer disease, low-grade B-cell mucosa associated lymphoid tissue lymphoma of the stomach, and gastric adenocarcinoma, which is the third leading cause of cancer death worldwide. The routes of infection have not yet been firmly established, and different routes of transmission have been suggested, although the most commonly accepted hypothesis is that infection takes place through the faecal-oral route and that contaminated water and foods might play an important role in transmission of the microorganism to humans. Furthermore, several authors have considered H. pylori to be a foodborne pathogen because of some of its microbiological and epidemiological characteristics. H. pylori has been detected in drinking water, seawater, vegetables and foods of animal origin. H. pylori survives in complex foodstuffs such as milk, vegetables and ready-to-eat foods. This review article presents an overview of the present knowledge on the microbiological aspects in terms of phenotypic characteristics and growth requirements of H. pylori, focusing on the potential role that foodstuffs and water may play in the transmission of the pathogen to humans and the methods successfully used for the detection of this microorganism in foodstuffs and water
Parabolic solutions for the planar N-centre problem: multiplicity and scattering
No full textFor the planar N-centre problem we prove the existence of entire parabolic trajectories, having prescribed asymptotic directions for t→±∞ and prescribed topological characterization with respect to the set of the centres
RIGHT VENTRICULAR MYOCARDIAL FUNCTION IN ARF PATIENTS: PEEP AS A CHALLEGNE FOR RIGHT HEART - REPLY
No full textMinori autori di reato: la valutazione della imputabilità sotto il profilo della maturità
No full text
Effects of PEEP on intrathoracic and extrathoracic blood volumes evaluated with the COLD system in patients with acute respiratory failure. Preliminary study
No full textAIM OF THE STUDY:
To evaluate the effects of positive end expiratory pressure (PEEP) on intrathoracic and extrathoracic blood volumes in patients with acute respiratory failure (ARF).
METHODS:
In 4 ARF patients, we have measured cardiac output (CI), intrathoracic blood volume (ITBVI), global end-diastolic ventricular volume (GEDVI), pulmonary (PBVI) and total (TBVI) blood volumes, during application of two PEEP levels (0 and 10 cm H2O). These measurements have been performed by PULSION COLD Z-021 system, using the double indicator dilution technique (thermal and dye dilution).
RESULTS:
PEEP application caused a significant reduction in CI (from 3.8 +/- 0.4 to 2.9 +/- 0.1 1/min/m2) and ITBVI (from 888 +/- 48 to 698 +/- 25 ml/m2). The reduction in intrathoracic blood volume was associated with a significant reduction in GEDVI and PBVI. After PEEP application, there was a significant reduction in TBVI (from 2437 +/- 135 to 1984 +/- 49 ml/m2).
CONCLUSIONS:
PEEP application decreases cardiac index, mainly through a preload reduction, as evidenced by the reduction in intrathoracic and end-diastolic ventricular blood volumes. The preload effect is due to an increase in intrathoracic pressure with reduction in total circulating blood volume. TBVI reduction is consistent with blood pooling in vascular compartments, e.g., splanchnic compartment, characterized by long vascular time constant
Monitoring atracurium neuromuscular block: comparison of single twitch and train of four
No full textOnset time and duration of action were monitored in three groups of 13 patients each, using different patterns of neuromuscular stimulation (single twitch stimulation, STS at 10 sec intervals and train of four, TOF, at 10, and 20 sec intervals) to assess: 1) the correspondence between the single twitch and the first TOF twitch; 2) the importance of the stimulation interval. The results show that onset time is longer and the duration of action is shorter when STS or TOF is used at 20 sec intervals in comparison to TOF at 10 sec intervals
Busi, B. (a cura di) (2020), Separate in casa. Lavoratrici domestiche, femministe e sindacaliste: una mancata alleanza, Roma, Ediesse, pp. 244
No full textAG About Gender - Rivista internazionale di studi di genere, V. 10 N. 19 (2021): Fare maschilità online: definire e indagare la manospher
Intrinsic PEEP and cardiopulmonary interaction in patients with COPD and acute ventilatory failure
No full textDeviation of end-expiratory lung volume from the elastic equilibrium volume of the respiratory system is recognized as a cardinal feature in mechanically-ventilated patients with severe chronic obstructive pulmonary disease (COPD) and acute ventilatory failure (AVF). The presence of dynamic hyperinflation implies that alveolar pressure remains positive throughout expiration. At the end of the expiration, this positive pressure is named intrinsic positive end-expiratory pressure (PEEPi). Recent studies have suggested that, in COPD patients with expiratory flow limitation, the application of external PEEP during assisted mechanical ventilation, or the use of continuous positive airway pressure (CPAP) in spontaneously breathing patients, can counterbalance and reduce the inspiratory threshold load imposed by PEEPi, without causing further increase in lung volume and alveolar and intrathoracic pressures until a critical value of PEEP (Pcrit) is reached. Above this critical limit further hyperinflation is observed. A specific and characteristic role of PEEPi in compromising the heart function in COPD patients during AVF may be identified based on: 1) an increase in right ventricular impedance due to lung hyperinflation; 2) an increase in the venous return to the right ventricle and, consequently, a leftward shift of the septum caused by the large negative deflections in intrathoracic pressure due to the inspiratory threshold load; 3) a further increase in venous return to the right ventricle, with the eventual collapse of the vena cava caused by the expiratory recruitment of abdominal muscles; and 4) hypoxia and hypercapnia consequent to acute ventilatory failure, which may further increase right ventricular impedance and venous return to the right ventricle. All these phenomenon are directly correlated to the large negative intrathoracic pressure developed by the respiratory muscles to overcome the inspiratory threshold caused by intrinsic positive end-expiratory pressure (preload effect), and to the increase in lung volume (afterload effect). Application of positive end-expiratory pressure/continuous positive airway pressure in chronic obstructive pulmonary disease patients during acute ventilatory failure may, hence, unload the respiratory muscles as well as the heart
Proteolytic and milk clotting activities in extracts obtained from the crustaceans Munida
No full textIn the present study, individuals of the crustaceans Munida have been investigated as a possible source of enzymes to be
used in cheese making as an alternative to calf rennet. The crustaceans were blended and the extracts were filtered and tested
for their proteolytic activity and milk clotting capability. The optimal values of pH and temperature of the total proteolytic
activity determined on azocasein were in the ranges pH 6.5–7.5 and 55–60 ◦C, respectively. The extracts showed a higher
capability to cleave S1-casein than - and k-casein. As determined with specific inhibitors, using azocasein or zymography,
the extracts appeared to contain serine proteases as well as cysteine and aspartic proteases. Hydrolysis of -casein gave
peptides which were different from those obtained with trypsin or a commercial calf rennet. Moderate milk clotting activity
was also present.
The ability to cleave casein, in particular S1-casein, and the moderate clotting activity, indicate that the extracts of the
crustaceans Munida could be useful in the dairy industry both for milk clotting, as an alternative or in addition to calf rennet,
and for the acceleration of cheese ripening in order to reduce time and costs of storage and maturation of cheese
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