47,140 research outputs found

    Maria Rebecca Ballestra: absence between Nature and Human Being in Echoes of the Void.

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    Maria Rebecca Ballestra (1974–2020) was an Italian artist whose work focused on ecology, climate change, and the Anthropocene. In Echoes of the Void (2015–2020), one of her latest projects, the absence of humans is central: photographs of the world’s largest deserts convey a sense of emptiness and highlight Nature’s persistence. The work challenges conventional perceptions of deserts as empty, isolated spaces, instead presenting them as sites that disorient, test, and accompany the individual. This paper examines how her work explores the dynamics between Nature and Humanity

    Somatically evoked cough responses help to identify patients with difficult-to-treat chronic cough: a six-month observational cohort study

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    Background: Recently we identified in patients with chronic cough a sensory dysregulation via which the urge-to-cough (UTC) or coughing are evoked mechanically from “somatic points for cough” (SPCs) in the neck and upper trunk. We investigated the prevalence and the clinical relevance of SPCs in an unselected population of patients with chronic cough. Methods: From 2018 to 2021, symptoms of 317 consecutive patients with chronic cough (233 females) were collected on four visits (V1–V4) 2 months apart at the Cough Clinic of the University Hospital in Florence (I). Participants rated the disturbance caused by the cough (0–9 modified Borg Scale). We attempted to evoke coughing and/or UTC using mechanical actions in all participants who were subsequently categorised as responsive (somatic point for cough positive, SPC+) or unresponsive (SPC−) to these actions. An association was established between chronic cough and its commonest causes; treatments were administered accordingly. Findings: 169 patients were SPC+ and had a higher baseline cough score (p < 0.01). In most of the patients, the treatments reduced (p < 0.01) cough-associated symptoms. All patients reported a decrease (p < 0.01) in cough score at V2 (from 5.70 ± 1.4 to 3.43 ± 1.9 and from 5.01 ± 1.5 to 2.74 ± 1.7 for SPC+ and SPC− patients respectively). However, whilst in SPC− patients the cough score continued to decrease indicating virtually complete cough disappearance at V4 (0.97 ± 0.8), in SPC+ patients this variable remained close to V2 values during the entire follow-up. Interpretation: Our study suggests that the assessment of SPCs may identify patients whose cough is unresponsive and are eligible for specific treatments. Funding: This work was funded by an unrestricted grant from Merck (Italy)

    G. M. Hopkins

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    [sound recording] / Brendan O'Grady. G. B. Shaw by Fran Frazer.; 1 sound cassette (60 minutes); Broadcast on CFCY Radio, Charlottetown, March 07 & 11, 1974.; G. B. ShawSource type: Electronic(1

    Optical coherence tomography and infrared images of astrocytic hamartomas not revealed by funduscopy in tuberous sclerosis complex

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    PURPOSE:To detect, describe, and classify the morphologic characteristics of astrocytic hamartomas in tuberous sclerosis complex, using both spectral-domain optical coherence tomography (OCT) and infrared images. METHODS: Ten subjects (20 eyes) with tuberous sclerosis complex underwent a complete ophthalmologic examination and multimodality imaging with spectral-domain OCT and infrared images. The imaging protocol included a 30°scan angle of the posterior pole and of the four quadrants. Line scans, detail, raster, and posterior pole patterns were used. The identified astrocytic hamartomas were described and characterized qualitatively and quantitatively. RESULTS: Forty-four hamartomas were detected in 8 patients. In five cases, lesions were bilateral. Thirty of these hamartomas had not been revealed by previous ophthalmoscopy. Through multimodality imaging, it was possible to define multiple lesions with characteristic optical reflective qualities. All the 44 hamartomas were measured and morphologically characterized in terms of the type of tumor, retinal and/or vitreous involvement, calcifications, and posterior optical shadowing. CONCLUSION: The combined imaging with spectral-domain OCT and infrared images improves the detection of hamartomas if compared with the spectral-domain OCT technique alone. Moreover, a new subtype of hamartoma is proposed to complete a previous classification based on OCT
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