178,980 research outputs found
Interactions between low-angle normal faults and plutonism in the upper crust: Insights from the island of Elba, Italy: Comment
The interplay between magmatism and tectonics is pivotal for deciphering the tectonic and geodynamic evolution of mountain belts. In the northern Apennines - northern Tyrrhenian Sea orogenic system large amounts of magma were emplaced at shallow crustal levels since the middle-late Miocene to recent (e.g. Serri et al., 1993; Rosenbaum et al., 2008). In this sector of the Apennine chain the mutual relationships between magmatism and tectonics are still a matter of debate (e.g., Rossetti et al., 1999; Acocella and Rossetti, 2002; Musumeci et al., 2005; 2008; Rosenbaum et al., 2008). Elba Island, located in the Tyrrhenian Sea about 30 km west of the inner portion of the chain, is a key area where tectonics - magmatism relationships can be studied
Expression and localization of aquaporin-1 in temporomandibular joint disc with internal derangement
J Oral Pathol Med. 2012 May 3. doi: 10.1111/j.1600-0714.2012.01156.x. [Epub ahead of print]
Expression and localization of aquaporin-1 in temporomandibular joint disc with internal derangement.
Loreto C, Galanti C, Almeida LE, Leonardi R, Pannone G, Musumeci G, Carnazza ML, Caltabiano R.
Source
Department of Bio-Medical Sciences, University of Catania, Catania, Italy Department of Dentistry, Faculty of Dentistry, University of Catania, Policlinico Universitario, Catania, Italy Center for Health and Biological Sciences, Pontifical Catholic, University of Panarà, Curitibe, Brazil Department of Surgical Sciences, Institute of Pathology and Cytopathology, University of Foggia, Foggia, Italy Department of Anatomy, Diagnostic Pathology, Forensic Medicine, Hygiene and Public Health, University of Catania, Catania, Italy.
Abstract
Internal derangement is the most J Oral Pathol Med (2012) Background: frequent arthropathy affecting the temporomandibular joint, where its commonest form is anterior disc displacement with or without reduction. Despite the frequency of the disorder, the biochemical features of displaced discs are still We investigated the expression pattern and localization of unclear. Methods: aquaporin-1, an important channel protein involved in plasma membrane water permeability, in patients with anterior disc displacement (both with and without reduction), with a view to assessing the characteristics of local tissue responses to the microenvironmental changes induced by abnormal mechanical loading of the displaced disc. Protein expression was studied by immunohistochemistry in different areas of discs from 18 patients with anterior disc displacement with or without reduction and in four normal controls. A greater proportion of cells immunopositive for aquaporin-1 were Results: detected in diseased than in normal discs. Whereas protein expression was substantially similar in the different areas of normal discs, a significantly larger number of immunopositive cells were detected in the posterior band of displaced discs without reduction and in the anterior and intermediate bands of These findings suggest that aquaporin-1 is those with reduction. Conclusions: expressed and upregulated in temporomandibular joint with anterior disc displacement (both with and without reduction)
Artificial Neural Networks, Dynamical Systems and Self-Organization
The world around us and the living beings are complex dynamical systems, with a high capability of self-organization: the book explains the principles that rule this exceptional characteristic. As well as living beings, Artificial Neural Networks, that constitute one of the most promising tools for the development of Artificial Intelligence, are self-organizing dynamical systems: this makes them an optimal tool to analyze and simulate the brain and any expression of organized complexity
Disuguaglianze di genere nell’Università che cambia: un’analisi del reclutamento nel sistema accademico
Just a Matter of Time? Women’s Career Advancement in Neo-Liberal Academia. An Analysis of Recruitment Trends in Italian Universities
Recently, the Italian higher education system has experienced two profound changes: the strong feminization of its academic staff and the implementation of market-based reforms aimed at fostering cost efficiency and economic productivity. Such reforms include the reshaping of the academic career ladder envisaged by the last university reform, the so called Gelmini reform (law 240/2010), and the adoption of a performance-based funding system. Both elements occurred in parallel with a strong cut in turnover. By accessing unique data on recruitment covering the last two decades, which were provided by the Italian Ministry of Education, University, and Research's statistical office, this study aims at investigating these changes from a gendered perspective. More specifically, it firstly aims at analyzing if the feminization of the academic staff is due to an effective improvement of gender equality in recruitment or, rather, to demographic dynamics; secondly, it investigates to what extent the recent neo-liberal transformations, and more specifically the reshaping of the career structure combined with the limitations on hiring, has had any implications in terms of women's recruitment and advancement. The results suggest that the road to gender equality is extremely slow and non-linear. The introduction, with the Gelmini reform, of the new fixed-term assistant professor has tightened female access to the tenure track. Moreover, female recruitment remained substantially unchanged over the period among associate and full professors, thus suggesting that the feminization of the academic staff is not due to an effective improvement of gender equality in recruitment, but also to demographic dynamics, such as the retirement of men who are concentrated in the older cohorts
Why so slow?» Un’analisi del reclutamento accademico in Italia dal 2000 al 2020, tra processi di femminilizzazione e (ri-)maschilizzazione
Analizzando i dati sul reclutamento per genere nel periodo 2000-2020 forniti dal Ministero dell'Università e della Ricerca (MUR), il presente contributo intende capire in che misura la femminilizzazione che l’università italiana sta attraversando da alcuni decenni corrisponda a un effettivo miglioramento dell’equilibrio di genere nel reclutamento o, al contrario, risenta di dinamiche demografiche o di passaggi di carriera. L’analisi nel tempo, per fascia, area disciplinare e geografica, consente di identificare dove si annidano eventuali fenomeni di rallentamento nel processo di femminilizzazione, se non di inversione di tendenza (backlash) e quindi di ri-maschilizzazione
Cryopreserved Penile Tunica Albuginea for Allotransplantation: A Morphological and Ultrastructural Investigation
Introduction. Peyronie's disease, a connective tissue disorder of penile tunica albuginea (TA) associated with penile deformity, curvature, pain, and erectile dysfunction, is best managed surgically, but suitable graft biomaterials are not available. Aim. To establish whether cryopreservation affects human TA in view of its use in allotransplants. Methods. The effects on TA samples of the two most widely used tissue cryopreservation methods were investigated using an ad hoc panel of histochemical, immunohistochemical, and ultrastructural tests. Apoptotic cells were evaluated using the terminal deoxynucleotidyl transferase method of end labeling (TUNEL) assay. Main Outcome Measures. Assessment of tissue integrity and arrangement of collagen and elastic fibers in thawed TA. Results. Both cryofixation methods provided TA tissue suitable for use as graft material. Significant ultrastructural changes, namely, a greater diameter of collagen fibrils, were detected in sections preserved in liquid nitrogen; nonetheless, such increase never exceeded the normal range. The comprehensive panel of assays used proved suitable to characterize the thawed tissue. Conclusion. Human TA is suitable for cryopreservation; freezing at -80°C provides better results than preservation in liquid nitrogen. Loreto C, Orlandi A, Ferlosio A, Djinovic R, Basic D, Bettocchi C, Rutigliano M, Barbagli G, Vespasiani G, Caltabiano R, Musumeci G, and Sansalone S. Cryopreserved penile tunica albuginea for allotransplantation: A morphological and ultrastructural investigation. J Sex Med **;**:**-**
Alpine tectonothermal evolution of the Tuscan Metamorphic Complex in the Larderello geothermal field (northern Apennines, Italy)
On the internal (Tyrrhenian) side of the northern Apennines, high heat flow and geothermal gradient
in the Larderello geothermal field are evidence of a large-scale thermal anomaly, related to the emplacement
of a large batholith of Pliocene age extending from the upper to middle crust. These intrusions relate to the
Miocene to Recent northern Apennines magmatism, which developed as a result of crustal extension and
upwelling of the asthenosphere at the base of the thinned crust. In the subsurface of the Larderello geothermal
field, medium- and high-grade metamorphic rocks (Tuscan Metamorphic Complex) cored in several
geothermal wells, have previously been considered to be Variscan basement. New structural and petrographic
data on these metamorphic rocks indicate an Alpine tectonometamorphic history and provide evidence that
medium- to high-grade mineral assemblages are related to Pliocene thermal metamorphism centred on
intrusions at shallow depth. These data allow a new interpretation of the Tuscan Metamorphic Complex as a
tectonic wedge of the Late Palaeozoic–Triassic units, and in particular highlight the considerable extent of
Pliocene thermal metamorphism and hydrothermal circulation as a result of convective cooling of intrusions
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