120 research outputs found
Assessment of Economic Growth of the Republic of Moldova in the Context of Global Economic Crisis
No full textThe world economic crisis has had a negative impact on the economic development of Moldova, but recent trends show that in 2010 we were able to forecast a small economic growth. The author examines the problems faced by the Moldavian economy which shackle its strong recovery. The current evolutions of the Moldavian economy are analyzed in the paper as well.remittances, foreign trade, competitiveness, structural reforms, macroeconomic environment
Efficacy of topical clobetasol propionate in the treatment of idiopathic granulomatous mastitis
No full textObjectives: To evaluate the efficacy of topical clobetasol propionate 0.05% pomade in the treatment of idiopathic granulomatous mastitis. Patients and Methods: Twenty-one idiopathic granulomatous mastitis patients' clinical and histopathological fmdings were retrospectively reviewed. Those patients excluded from other etiologies were categorized as idiopathic granulomatous mastitis and treated with topical clobetasol propionate 0.05% pomade as an initial treatment. Results: All 21 patients with a fmal diagnosis of idiopathic granulomatous mastitis were women with the average age of 36.2+/-5.2 years. Of the 21 patients; erythema, induration and pain problems of 6 (28.5%) patients totally resolved without recurrence in 3 months follow-up period. Erythema, induration and pain problems of 7 (33.5%) patients were minimalized and stay stable in 3 months follow-up period. The symptoms of 8 (38%) did not change under topical clobetasol propionate treatment. None of the patients developed side or adverse effects due to topical steroid treatment and 6 of 18 patients with non-steroidal anti-inflammatory drugs (NSAIDs) complained of gastric pain. Conclusion:Topical steroid treatment is a safe treatment option for idiopathic granulomatous mastitis patients before systemic steroid and immunosuppressive treatments and also surgery
Effects of Intraperitoneal Sildenafil Administration on Healing of Left Colonic Anastomoses and Intra-Abdominal Adhesion Formation in the Presence of Intra-Abdominal Infection
No full textA novel artificial neural network model for forecasting electricity demand enhanced with population-weighted temperature mean and the unemployment rate
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Effects of Sildenafil Citrate on Ischemic Colonic Anastomotic Healing in Rats: Its Relationship Between Nitric Oxide and Oxidative Stress
No full textTo the Editor, We read with great interest the article by Uzun et al. [1], whose work shows that sildenafil citrate therapy might improve anastomotic healing by its effect on nitric oxide (NO) and oxidative stress metabolism. We would like to expand on this concept by introducing a major route by which sildenafil citrate could potantiate platelet inhibition and improve microcirculation. Phosphodiesterase-5 (PDE-5) inhibitors prevent the breakdown of nitric oxide–derived cGMP, primarily in vascular smooth muscle cells, and they thus cause vasodilation. Several investigators have shown that mucosal injury to the gastrointestinal system may be caused by platelet activating factor (PAF), which is known for its vasoactive properties; in the mesenteric region, PAF causes vasoconstriction and tissue hypoperfusion, which may lead to gastrointestinal mucosal ulceration [2, 3]. Platelets have also been well studied with respect to PDEs, and cGMPdependet protein kinase has been shown to play an important role in platelet inhibition by NO. Hart et al. [4] have reported that sildenafil therapy significantly improved postoperative skin flap viability by improving microcirculation and platelet inhibition. In a recent study we found that sildenafil reduced the degree of ischemic intestinal mucosal damage by its effects on the vascular smooth muscle and the microcirculatory hemodynamics related to platelet function [5]. This important mechanism should be borne in mind, as it may be of interest in examining the potential benefical effects of this drug in a model of acute mesenteric ischemia with nonocclusive vasospastic diseases
A change-point based reliability prediction model using field return data
No full textIn this study, we propose an accurate reliability prediction model for high-volume complex electronic products throughout their warranty periods by using field return data. Our model has a specific application to electronics boards with given case studies using 36-month warranty data. Our model is constructed on a Weibull-exponential hazard rate scheme by using the proposed change point detection method based on backward and forward data analysis. We consider field return data as short-term and long-term corresponding to early failure and useful life phases of the products, respectively. The proposed model is evaluated by applying it to four different board data sets. Each data set has between 1500 and 4000 board failures. Our prediction model can make a 36-month (full warranty) reliability prediction of a board with using its field data as short as 3 months. The predicted results from our model and the direct results using full warranty data match well. This demonstrates the accuracy of our model. We also evaluate our change point method by applying it to our board data sets as well as to a well-known heart transplant data set. (C) 2016 Elsevier Ltd. All rights reserved
Seismic upgrade of RC buildings using CFRP sheets
No full textProtupotresno poboljšanje postojećih građevina s armiranobetonskom okvirnom konstrukcijom obično zahtijeva iseljenje stanara, a često su i kratki vremenski rokovi za izvođenje građevinskih radova. Ovakvi problemi uglavnom dovode do kašnjenja i dodatnih troškova u projektima protupotresne obnove. Jedan od načina poboljšanja seizmičke otpornosti konstrukcije je uporaba CFRP (ugljičnim vlaknima ojačanog polimera) traka i čeličnih spona. U radu je na temelju provedenih analiza dokazana ekonomičnost i praktičnost ovog tehničkog rješenja.The seismic upgrade of existing reinforced-concrete frame buildings usually calls for evacuation of occupants, and the time available for construction works is often quite limited. These problems usually cause time delays and additional costs on seismic rehabilitation projects. One of the ways of improving seismic resistance of structures is to use CFRP (carbon fibre-reinforced polymer) sheets and steel fuse elements. The cost-effectiveness and practical value of this technical solution is proven in the paper through appropriate analyses
Multiple perforations along the transverse colon as a rare presentation of intestinal behcet's disease: a case report
No full textBehcet’s Disease (BD) is a rare and lifelong disorder characterized by inflammation of blood vessels throughout the body.1 BD is much more prevalent in countries along the ancient silk road from eastern Mediterranean countries to Eastern Asia.1,2 Some environmental factors are proposed for the etiology.3 Since Behcet’s4 original description in 1937, many other manifestations have been added to the original triad. Diagnostic criteria for BD were defined by the international study group for BD in 1990.5 Although the etiology of BD is unknown, it is likely due to an autoimmune vasculitis in genetically predisposed individuals triggered by an infectious agent or other antigens.2,6 BD mostly affects children and young adults between the second and fourth decades of life7. Those affected before the age of 25 years (early onset) and males have been shown to have more severe disease symptoms.8 Treatment of BD is usually palliative and symptomatic. Antibiotic, antiviral, corticosteroid, immunosuppressive and cytotoxic agents are used for treatment according to the symptoms. Unlike neuro-Behcet’s, entero-Behcet’s causes intestinal perforation/bleeding and some vascular lesions.9–11 The syndrome usually runs a relatively benign course with exacerbations and remissions. Gastrointestinal involvement of BD is rare.9 Common gastrointestinal sites affected by BD other than the mouth are the ileocecal region and the colon. There are only a few studies reporting colonic perforations due to BD. In this article, we report a patient with BD who underwent an emergency operation for acute abdomen that developed secondary to multiple perforations of the transverse colon. The patient had a good response to surgical treatment followed by corticosteroids, immunosuppressant drugs and colchicine
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