305,284 research outputs found
Incontro e Workshop: New Hampshire University for DISIA
No full textIncontro e workshop ad Ascoli Piceno tra gli studenti della New Hampshire University e quelli del Corso di Laurea in Disegno Industriale e Ambientale dell’Università di Camerino si è svolto il 10 giugno 2011. L’incontro-workshop, organizzato con Cristian Muscelli, Direttore della New Hampshire University in Ascoli Piceno, si è posto l’obiettivo di favorire l’integrazione e lo scambio culturale tra gli studenti delle due università presenti nella città di Ascoli Piceno, attraverso la condivisione di elaborati estemporanei di carattere pittorico realizzati da gruppi eterogenei di studenti, che riproducono brani della città di Ascoli Piceno. L’incontro si è concluso con una discussione tra i gruppi riguardo le modalità e le scelte operate per la realizzazione delle opere
"Fantasie sul cibo". Incontro con Cristian Muscelli, filosofo e psicoterapeuta
No full textNel seminario, che si è svolto il 12 Novembre 2019 presso la sede della Scuola di Architettura e Design dell’Università di Camerino di Sant’Angelo Magno, Cristian Muscelli, filosofo e psicoterapeuta, Program Director at University of New Hampshire, ha illustrato e discusso diversi aspetti, filosofici, culturali, psicologici di natura comunicativa del cibo
Improved tolerance to sequential glucose loading (Staub-Traugott effect): size and mechanisms
No full textBonuccelli S, Muscelli E, Gastaldelli A, Barsotti E, Astiarraga BD, Holst JJ, Mari A, Ferrannini E. Improved tolerance to sequential glucose loading (Staub-Traugott effect): size and mechanisms. Am J Physiol Endocrinol Metab 297: E532-E537, 2009. First published June 16, 2009; doi:10.1152/ajpendo.00127.2009. - Improved glucose tolerance to sequential glucose loading (Staub-Traugott effect) is an important determinant of day-to-day glycemic exposure. Its mechanisms have not been clearly established. We recruited 17 healthy volunteers to receive two sequential oral glucose tolerance tests (OGTTs), at time 0 min and 180 min (Study I). The protocol was repeated on a separate day (Study II) except that plasma glucose was clamped at 8.3 mmol/l between 60 and 180 min. beta-Cell function was analyzed by mathematical modeling of C-peptide concentrations. In a subgroup, glucose kinetics were measured by a triple-tracer technique (infusion of [6,6-(2)H(2)] glucose and labeling of the 2 glucose loads with [1-(2)H] glucose and [U-(13)C] glucose). In both Studies I and II, the plasma glucose response to the second OGTT equaled 84 +/- 2% (P = 0.003) of the response to the first OGTT. Absolute insulin secretion was lower (37.8 +/- 4.3 vs. 42.8 +/- 5.1 nmol/m(2), P = 0.02), but glucose potentiation (i. e., higher secretion at the same glycemia) was stronger (1.08 +/- 0.02 vs. 0.92 +/- 0.02-fold, P = 0.006), the increment being higher in Study II (+36 +/- 5%) than Study I (+19 +/- 6%, P < 0.05). In pooled data, a higher glucose area during the first OGTT was associated with a higher potentiation during the second OGTT (rho = 0.60, P = 0.002). Neither insulin clearance nor glucose clearance differed between loads, and appearance of glucose over 3 h totalled 60 +/- 6 g for the first load and 52 +/- 5 g for the second load (P = not significant). Fasting endogenous glucose production [13.3 +/- 0.6 mu mol.min(-1).kg fat-free mass (FFM)(-1)] averaged 6.0 +/- 3.8 mu mol.min(-1).kg FFM(-1) between 0 and 180 min and 1.7 +/- 2.6 between 180 and 360 min (P < 0.03). Glucose potentiation and stronger suppression of endogenous glucose release are the main mechanisms underlying the Staub-Traugott effect
Istantaneità. Cultura e psicopatologia della temporalità contemporanea
No full textLaddove la cifra della temporalità dell’epoca moderna è stata la velocità, il tratto essenziale del mondo contemporaneo è l’istantaneità – una nuova forma del tempo che si fonda e conclude nell’unità assoluta dell’istante. Questo volume si interroga su come la mutazione del mondo contemporaneo – il presentismo – contrassegni una radicale mutazione delle forme di patologia mentale
La vulnerabilità ai tempi dell’istantaneità: il presente e la condizione borderline (Vulnerability in the time of instantaneity. The present and the borderline condition)
No full text“Filosofia del cibo”. Incontro con Cristian Muscelli. Filosofo
No full textIl filosofo Cristian Muscelli ha illustrato il rapporto tra filosofia e cibo con costanti riferimenti alla condizione dell'uomo contemporaneo
Alterazioni subcliniche della funzione diastolica miocardica e resistenza insulinica in soggetti obesi senza comorbidità
No full text
Relation of aortic stiffness with indices of LV diastolic filling and myocardial longitudinal function in subjects free of clinical cardiovascular disease
No full textRetinol-binding protein-4 in women with untreated essential hypertension
No full textBACKGROUND:
Retinol-binding protein-4 (RBP4) is a novel adipokine able to modulate the action of insulin in several tissues. A variable degree of insulin resistance characterizes the vast majority of hypertensive (HYP) patients. The aim of this study was to evaluate the relationship between RBP4 and essential hypertension, exploring potential links between RBP4 and other adipokines with some proxies of early vascular damage in female naive HYP patients.
METHODS:
Serum RBP4, leptin, adiponectin, and resistin levels were determined in 35 HYP and 35 normotensive lean women with normal glucose tolerance paired by age and body mass index (BMI) served as controls (CTL); carotid intima-media thickness (IMT) was also measured.
RESULTS:
A striking difference was observed in RBP4 levels between HYP and CTL with significantly higher levels in the former than in the latter. No relationship was observed between glomerular filtration rate (GFR) and RBP4. Adiponectin levels were slightly but significantly lower in HYP than in CTL, whereas no differences were observed in resistin and leptin concentrations between the two groups of women. In the whole study group, a strong linear relationship was observed between IMT value and both RBP4 (rho = 0.321, P = 0.0076) and resistin (rho = 0.340, P = 0.0048); these two adipocytokines, together with cholesterol, were the only variables independently related to IMT (r(2) = 0.24; P = 0.004) by a stepwise analysis.
CONCLUSIONS:
RBP4 levels are increased in naive HYP women and correlated with the degree of IMT suggesting a participation of this adipocytokine in the modulation of the atherosclerotic process exerted by the adipose tissue as endocrine organ
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