389 research outputs found
Natural Variation of the Circadian Clock in Neurospora
No full textMost living organisms on earth experience daily and expected changes from the rotation of the earth. For an organism, the ability to predict and prepare for incoming stresses or resources is a very important skill for survival. This cellular process of measuring daily time of the day is collectively called the circadian clock. Because of its fundamental role in survival in nature, there is a great interest in studying the natural variation of the circadian clock. However, characterizing the genetic and molecular mechanisms underlying natural variation of circadian clocks remains a challenging task. In this chapter, we will summarize the progress in studying natural variation of the circadian clock in the successful eukaryotic model Neurospora, which led to discovering many design principles of the molecular mechanisms of the eukaryotic circadian clock. Despite the success of the system in revealing the molecular mechanisms of the circadian clock, Neurospora has not been utilized to extensively study natural variation. We will review the challenges that hindered the natural variation studies in Neurospora, and how they were overcome. We will also review the advantages of Neurospora for natural variation studies. Since Neurospora is the model fungal species for circadian study, it represents over 5 million species of fungi on earth. These fungi play important roles in ecosystems on earth, and as such Neurospora could serve as an important model for understanding the ecological role of natural variation in fungal circadian clocks.Advances in Genetics, Vol. 99
Herida de bala de aorta
Full text linkThe author presents the case of a 16-year old girl with a bullet wound in the abdominal aorta, operated under shock with two perfusions of rapid onset. Linen suture was performed and recuperation followed without sequella. This seems to be the first case published in Uruguay of survival of aortic wounds.Se relata una observación de herida de bala de aorta abdominal en una joven de 16 años, operada en colapso con dos venoclisis instaladas rápidamente. Se hizo sutura con lino obteniendo recuperación sin secuelas. Parece tratarse de la primera observación publicada en el país de heridade aorta con sobrevida
Dynamics of Network Formation Processes in the Co-Author Model
Full text linkThis article studies the dynamics in the formation processes of a mutual consent network in game theory setting: the Co-Author Model. In this article, a limited observation is applied and analytical results are derived. Then, 2 parameters are varied: the number of individuals in the network and the initial probability of the links in the network in its initial state. A simulation result shows a finding that is consistent with an analytical result for a state of equilibrium while it also shows different possible equilibria.Dynamics, Network, Game Theory, Model,Simulation, Equilibrium, Complexity
Solar powered charge stations for electric vehicles
Full text linkEvery hour, the sun emits more energy onto the Earth’s surface than our entire world population uses in one year. [1] Solar power provides us with the possibility of a cleaner and more renewable future. Global climate change as a result of greenhouse gases and the effects of low air quality caused by pollutants have become very substantial issues in our world today. The costs associated with greenhouse gas and air pollutant emissions, and the effect they have on human lives and human health, are major and growing concerns. The development and installation of solar powered charging stations will reduce the amount of greenhouse gases emitted into the atmosphere, future costs associated with climate change, and health issues. Thus, there is environmental, social, and economic value associated with the installation of solar powered charge stations. Solar powered charging stations have the potential of significantly reducing air pollutants and improving urban air quality. The electrification of transportation and the use of solar powered charging stations as an electricity source will improve people’s quality of life
Dataset for the paper "Climate model bias indicates higher projected future temperature extremes"
No full text<div>
<div>This repository holds data and scripts used to produce the paper entitled:</div>
<br>
<div>"Climate model bias indicates higher projected future temperature extremes"</div>
<br>
<div>by Lei Duan, Lyssa M. Freese, Govindasamy Bala, and Ken Caldeira.</div>
<br>
<div>The paper is currently submitted for peer review.</div>
<br>
<div>Any questions regarding the data and paper could be sent to the corresponding author: Lei Duan ([email protected])</div>
</div>
Improving Agricultural Irrigation on the Balkhab River, Afghanistan
Full text linkIn Afghanistan, where 80% of the population is rural, irrigated agriculture is important for satisfying subsistence needs. While most of the irrigated agriculture is fed by diversion canal systems which tap surface flows, legal and physical water infrastructure in the region is generally poor. A math programming model is used to optimize irrigation strategies under different water-availability and policy scenarios. It is found that the construction of a reservoir could increase net revenues to a representative farming community by up to 30%. However, even greater benefits may result from increasing distribution efficiencies, depending on the initial level of conveyance losses. Further, property rights schemes may be implemented to distribute wealth more evenly through various zones at minimal cost to the agricultural community as a whole. These results may prove useful to policymakers or water authorities in reestablishing water rights.linear programming, irrigation, Afghanistan, Agricultural and Food Policy, Community/Rural/Urban Development, International Development,
Halima C. Schmaling, Lawan Bala Hausawa (co-author of Book 1). Maganar Hannu. Harshen Bebaye na ƙasar Hausa/Hausa Sign Language. Liffafi na farko: Iyali/Book 1: Family, Kano: Good Image Printing Ltd., 2011, 28 pp; Littafi na biyu: Haɗuwa da sadarwa/Book 2: Meeting and communicating, Hamburg: Helmut Buske Verlag, 2013, 31 pp; Littafi na uku: Kwatancin mutane da abubuwa/Book 3: Describing people and things, Hamburg: Helmut Buske Verlag, 2016, 35 pp; Littafi na huɗu: Kasuwanci da kiɗaya/Book 4: Commerce and counting, Hamburg: Helmut Buske Verlag 2016, 32 pp; Littafi na biyar: Ayyukan yau da kullum/Book 5: Everyday activities, Hamburg: Helmut Buske Verlag, 2017, 35 pp.
No full textA review of series of books by Halima C. Schmaling, Lawan Bala Hausawa (co-author of Book 1). Maganar Hannu
Pre Clinical and Clinical Evaluation of Karappan Nei (Internal and External Medicine) in the treatment of Bala Karappan in Children
Full text linkThe disease Bala Karappan was taken for the clinical study with the trial drug Karappan Nei (Internal and External Medicine) after scrutinizing by the Screening committee of National Institute of Siddha.
Clinical studies were carried out after obtaining proper approval from IEC of National Institute of Siddha and the trial was registered in Clinical trial registry of India. The medicines were prepared after obtaining proper authentication of ingredients from Medicinal Botanist of National Institute of Siddha. Acute toxicity study, Physiochemical analysis, Phytochemical analysis and Pharmacological activity (anti – inflammatory) for the trial medicine was performed.
All the 30 patients were treated in OPD of Kuzhandhai Maruthuvam department at Ayothidoss Pandithar Hospital of National Institute of Siddha. The patients with Bala Karappan were recruited for this study based on Inclusion and Exclusion criteria and a detailed clinical study was done. Separate proforma was maintained for each patient along with SCORAD index chart on 0, 16th, 32th, 48th day to monitor the prognosis.
From the clinical study, it was inferred that Bala Karappan was affecting in the school going children (6-12 years) and the incidence was chronic in maximum number of patients. The trial drug was given two times in a day for 48 days. All the patients were advised to follow the strict diet regimen during the treatment.
The Bio chemical analysis of drug showed presence of Carbonate, Iron, Starch. The physicochemical analysis showed that the trial drug was in appropriate in consistency for this study. The phytochemical analysis of drug showed presence of Alkaloids, Flavonoids, Glycosides, Steroids, Triterpenoids, Coumarins, Phenol, Tannins.
The patients have not complained of any adverse effects or difficulties during the course of treatment. Thus the drug compliance was good with the patients of Bala Karappan.
The clinical efficacy of the trial drugs in children was analyzed statistically with all the symptoms mentioned in the assessment criteria and also through SCROAD index value.
The result were observed as follows,
Among 30 children, the symptoms of Bala Karappan like 80.0% Itching, 96.7% Papules, Vesicles, Blisters, Pustules, 46.7% Pain in lower extremities, 63.3% Ulcer formation with oozing, 93.3% sleep disturbances, 30.0% hyper pigmentation were improved clinically.
The signs and symptoms were reduced markedly in 30 cases by SCORAD value range of 75% -100%, and No cases have been identified the by SCORAD value range of 0%, <25% and 25% -50%, 50%-75%.
The mean and standard deviation of clinical symptoms of SCORAD index value for all the 30 patients before and after treatment is 50.293 ±9.923 and 4.876 ±3.417 respectively. The mean + S.D before and after treatment on SCORAD reveals that there is reduction of symptoms in after treatment i.e 90% reduction. It is statistically highly significant in reduction of eczema. The observation made during the study both clinically and statistically explores that the trail drug Karappan Nei was effective in the management of Bala Karappan in children.
CONCLUSION:
All the 30 patients clinically diagnosed as Bala Karappan were treated with Karappan Nei with the of dose for 5-10 ml Internally and also used as External medicine for two times a day for 48 days.
The efficacy of the trial drug for the management of Bala Karappan was significantly effective by means of SCORAD value. The reduction of clinical symptoms was highly significant (p < 0.001). The reduction in the clinical symptoms was 90% after treatment.
Pharmacological activity of Karappan Nei was showed that, the drug was having potent anti-inflammatory activity by In-vitro studies.
Hence the author strongly recommends that this trial drug Karappan Nei may be given to children without any hesitations for the management of Bala Karappan. The ingredients of the trial drug also cost effective. Further research works may be carried out in the large group of patients to explore this novel drug more scientifically
The murderer as writer, storyteller and protagonist : the case of Krystian Bala
Full text linkThis paper presents the results of the semiotic analysis in which the story of Krystian Bala, a Polish author who was convicted of murder, is studied in detail. The presented case study focuses on the interactions between real and fictional worlds, in particular, on the possibility of amalgamation of a real author’s and a fictional storyteller’s roles. Furthermore, the double-dimensional analysis of reality and fiction is complemented and broadened by an in-depth examination of how this story has inspired other authors. By discussing real events and texts of culture based on them, this paper aims at presenting the process in which the writer who had turned to be the murderer became the protagonist of artistic creations of others, and, in consequence, a part of a broader socio-cultural phenomenon
- …
