1,354,402 research outputs found
Chiara Villani Mularoni e la comunità di Faetano fra Otto e Novecento
No full textRicostruzione del contesto storico della Repubblica di San Marino fra Otto e Novecento e dell'opera di Chiara Villani Mularoni, una delle prime maestre elementari che ha insegnato nella seconda metà dell'Ottocento nel Castello di Faetano
A comparative evaluation of 2 Extended Depth-Of-Focus intraocular lenses in cataract surgery: results of a prospective randomized trial.
No full text
Topography-guided PRK-PTK to treat post-infective corneal scars
No full textPURPOSE: To evaluate corneal transparency and visual acuity changes in patients with corneal scars due to infective keratitis (Acanthamoeba -Pseudomonas Aeruginosa- Herpes– Contact Lens Related Corneal Ulcers) treated with topography-guided PRK-PTK. These patients would traditionally be candidates for corneal grafts.
METHODS: Five patients complaining of visual acuity reduction due to corneal scars were referred to our clinic for corneal transplants. Instead of corneal grafts, they were treated with topography-guided PRK-PTK (iResTM – IVIS technologies laser system, LIGI – Italy using the principles of CIPTA TM - Corneal Interactive Programmed Topographic Ablation). Patients were followed-up for at least 12 months.
RESULTS: In all cases we obtained an increase of corneal regularity with a reduction of corneal astigmatism leading to satisfactory improvement of visual acuity, such that corneal transplantation was not necessary.
CONCLUSION: Topography-guided PRK-PTK represents an interesting conservative treatment to improve visual acuity in patients with corneal scars otherwise requiring a corneal graft
HIV infection with viro-immunological dissociation in a patient with polycystic kidney disease: Candidate for transplantation?
No full textHere we describe the case of a HIV-infected patient with polycystic kidney disease and end stage renal diseases not transplantable due to the persistence of a CD4 count <200 notwithstanding a good virological response to highly active antiretroviral therapy and suggest that such limitation to kidney transplantation in such as cases might be bypassed
Ex vivo photoactivated chromophore for keratitis-corneal crosslinking on inverted graft: new approach to manage interface infectious keratitis after deep anterior lamellar keratoplasty
No full textA 44-year-old man affected by keratoconus underwent deep anterior lamellar keratoplasty (DALK). Two weeks postoperatively, slitlamp examination showed grayish-white lesions in the donor-host interface. Corneal scraping and donor broth culture tested negative for both bacteria and fungi. In vivo confocal microscopy showed elongated particles resembling Candida pseudofilaments. Despite antimicrobial therapy, the clinical picture worsened, and surgical approach was chosen: the graft was peeled off and inverted (epithelium facing down), and ex vivo photoactivated chromophore for infectious keratitis-corneal crosslinking (PACK-CXL) was performed; the recipient bed was washed with antibiotics/antifungals and the graft resutured. Microbiological and histological evaluations of biopsy specimen tested positive for Candida albicans. Postoperative slitlamp examination revealed a progressive recovery of graft transparency with disappearance of the infiltrates. To the authors' knowledge, this is the first report of ex vivo PACK-CXL on inverted DALK graft for the treatment of interface infectious keratitis. This technique allowed the resolution of the infection while sparing the use of new donor tissue
Evaluation of the Morphology of Ganglion Cell Complex and Functional Outcomes after Internal Limiting Membrane Peeling with Macular Abrasion in Idiopathic Macular Hole
No full textAim. This study aims to evaluate the morphology of ganglion cell complex (GCC) along with functional outcomes in patients undergoing vitrectomy with ILM peeling and macular abrasion with Tano diamond dusted membrane scrapers (DDMS) for three different stages of the idiopathic macular hole (IMH). Methods. This retrospective study was conducted between April 2019 and December 2019. 33 patients with IMH were included and divided into three groups: stage I, stage II, and stage IV. All patients were subjected to vitrectomy with ILM peeling. Gentle and vigorous macular abrasion was additionally performed for stage II and stage IV patients, respectively. The best-corrected visual acuity (BCVA), GCC thickness (measured by spectral domain-optical coherence tomography (SD-OCT)), and photopic contrast sensitivity (Rodenstock CV 900 Chart Panel) were determined before surgery and at 1- and 3-month follow-ups. Results. Closure of MH was achieved in all the patients. The difference between the preoperative and one- and three-month postoperative values of BCVA was statistically significant in the three groups (P<0.01). Contrast sensitivity progressively improved in all patients and was statistically significant (P<0.01). The reduction in GCC thickness during follow-up was 34%–42% of the preoperative measurements. On comparing the mean GCC thickness of the operated and healthy eyes, it was not statistically significant in stage I patients. However, the same when done in stage II and IV was statistically significant with P value < 0.05 and P<0.01, respectively. Conclusion. Combining ILM peeling with macular abrasion in advanced stages of MH may facilitate its closure without significantly affecting the functional outcome
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