42 research outputs found
Palladium chemistry in chemical biology
No full textA range of fluorescein derivatives were synthesised via Pd0-mediated cross-coupling
chemistry of the mono triflate of fluorescein with a variety of boronic acids and the
optical properties of each dye was studied. Among these derivatives, a new
multicolour pH–dependant anthofluorescein which was highly sensitive to pH
changes and viscosity changes was identified.
Work was carried out to explore intracellular catalysis based on the
immobilisation of Pd0 nanoparticles on microspheres. The entrapped Pd0
nanoparticles were rapidly taken up by cells, stay harmlessly within the cytoplasm
for days and were shown to carry out novel cell-based chemistry. This included an
allylcarbamate cleavage and a Suzuki-Miyaura cross-coupling reaction for the in situ
generation of a mitochondria-localized “switch-on” fluorophore
Palladium chemistry in chemical biology
No full textA range of fluorescein derivatives were synthesised via Pd0-mediated cross-coupling chemistry of the mono triflate of fluorescein with a variety of boronic acids and the optical properties of each dye was studied. Among these derivatives, a new multicolour pH–dependant anthofluorescein which was highly sensitive to pH changes and viscosity changes was identified. Work was carried out to explore intracellular catalysis based on the immobilisation of Pd0 nanoparticles on microspheres. The entrapped Pd0 nanoparticles were rapidly taken up by cells, stay harmlessly within the cytoplasm for days and were shown to carry out novel cell-based chemistry. This included an allylcarbamate cleavage and a Suzuki-Miyaura cross-coupling reaction for the in situ generation of a mitochondria-localized “switch-on” fluorophore.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
Low frequency sonochemical synthesis of nanoporous amorphous manganese dioxide (MnO2) and adsorption of remazol reactive dye
No full textRecent advances in detection techniques and chemometric methods for identifying adulterants in milk and dairy products
No full textMilk adulteration poses a significant threat to food safety, driven by increasing global demand for milk and dairy products, particularly in developing countries. Supply limitations, compounded by challenges like pandemics and livestock diseases such as mastitis, often lead to unethical practices that compromise product quality and consumer health. Adulterants, including preservatives, non-milk fats, thickening agents, nitrogen-based compounds, and surfactants, are intentionally added to mimic natural properties or enhance the solid-not-fat (SNF) content of milk. Advanced detection techniques, such as spectroscopy, chromatography, biosensors (protein and DNA-based), and electromigration methods like SDS-PAGE, have emerged as critical tools for identifying these adulterants. Innovative approaches, including electrical sensors like electronic noses and tongues, further enhance detection accuracy. This study highlights recent advancements in instrumental techniques alongside the pivotal role of chemometric methods in analyzing complex datasets, improving precision, and ensuring reliable detection, offering insights into current progress, challenges, and opportunities in safeguarding milk integrity
Green and nano-based strategies for controlling mild steel corrosion in acidic media: a systematic review
No full textAbstract Corrosion of mild steel in acidic media remains a major constraint in industrial processes, necessitating effective and sustainable protection strategies. This systematic review synthesizes evidence from 45 rigorously selected studies (2018–2025), identified through a PRISMA-guided screening of 676 records, to evaluate recent developments in green and nano-enabled corrosion inhibitors for acidic environments. A complementary bibliometric analysis using VOSviewer reveals four dominant research clusters focused on plant-based inhibitors, nanomaterials, adsorption mechanisms, and electrochemical evaluation techniques, highlighting an increasingly interconnected research landscape. Green inhibitors offer environmentally benign and low-toxicity corrosion mitigation but often suffer from thermal instability, compositional variability, and inconsistent performance. Nano-based inhibitors exhibit superior durability, high surface reactivity, and strong interfacial interactions, yet raise concerns regarding synthesis cost, potential toxicity, and long-term environmental impact. Hybrid green–nano systems show synergistic behaviour, enhanced film formation, and consistently high inhibition efficiencies, positioning them as strong candidates for advanced protection solutions. Despite these advances, important gaps persist, including limited industrial validation, inadequate environmental risk assessment, and the absence of standardized testing protocols. This review consolidates current knowledge and outlines key research priorities to guide the design of next-generation, sustainable corrosion inhibitors capable of delivering reliable performance under harsh acidic conditions
Development of a New Binary Solvent System Using Ionic Liquids as Additives to Improve Rotenone Extraction Yield from Malaysia Derris sp.
No full textRotenone is one of the prominent insecticidal isoflavonoid compounds which can be isolated from the extract of Derris sp. plant. Despite being an effective compound in exterminating pests in a minute concentration, procuring a significant amount of rotenone in the extracts for commercialized biopesticides purposes is a challenge to be attained. Therefore, the objective of this study was to determine the best ionic liquid (IL) which gives the highest yield of rotenone. The normal soaking extraction (NSE) method was carried out for 24 hrs using five different types of binary solvent systems comprising a combination of acetone and five respective ionic liquids (ILs) of (1) [BMIM] Cl; (2) [BMIM] OAc; (3) [BMIM] NTf2; (4) [BMIM] OTf; and (5) [BMPy] Cl. Next, the yield of rotenone, % (w/w), and its concentration (mg/mL) in dried roots were quantitatively determined by means of RP-HPLC and TLC. The results showed that a binary solvent system of [BMIM] OTf + acetone was the best solvent system combination as compared to other solvent systems (P<0.05). It contributed to the highest rotenone content of 2.69 ± 0.21% (w/w) (4.04 ± 0.34 mg/mL) at 14 hrs of exhaustive extraction time. In conclusion, a combination of the ILs with a selective organic solvent has been proven to increase a significant amount of bioactive constituents in the phytochemical extraction process
Morphological effect on conductivity performance of ZnO/carbon nanotubes cotton hybrid
No full textCarbon nanotubes cotton (CNTC) is a bulk form of superfiber materials with soft, fluffy textures and light weight consisted of lengthy thread network of carbon nanotubes physically resembles cotton fiber used in textiles industry. We reported CNTC as a substrate and hybridization of ZnO nanostructures onto the CNTC surface. ZnO buffer layer for growth patterning localization was firstly deposited onto CNTC using 99.9% ZnO target. ZnO nanostructures were then attached on the CNTC substrate via chemical bath deposition method. It was observed that the average diameter and length of the nanostructures were increased resulting in highest aspect ratio of 12. Higher temperature at 120 ℃ gave the best conductivity of 7.8 S/cm. The synthesized nanostructures on CNTC are comparable to those synthesized on other substrate such as glass and alumina. In addition, this hybrid offers promising future as CNTC substate is flexible, readily available and low cost than those substrates
Separation of free fatty acids from high free fatty acid crude palm oil using short-path distillation
No full text
