1,450 research outputs found
sj-docx-1-cath-10.1177_10760296211048815 - Supplemental material for COVID-19 Vaccine-Associated Thrombosis With Thrombocytopenia Syndrome (TTS): A Systematic Review and Post Hoc Analysis
No full textSupplemental material, sj-docx-1-cath-10.1177_10760296211048815 for COVID-19 Vaccine-Associated Thrombosis With Thrombocytopenia Syndrome (TTS):
A Systematic Review and Post Hoc Analysis by Muhammad Usman Hafeez, Maha Ikram, Zunaira Shafiq, Azza Sarfraz, Zouina Sarfraz, Vikash Jaiswal, Muzna Sarfraz and Ivan Chérrez-Ojeda in Clinical and Applied Thrombosis/Hemostasis</p
Ahmad Nawaz, Muhammad Sarfraz, Muhammad Sarwar, and Muhammad Farooq
No full textAllelopathy is a naturally occurring ecological phenomenon in which the livingorganisms produce and release the biochemicals (allelochemicals) in the environmentthat affect the growth, development, reproduction, and survival of otherliving organisms in the surrounding environment. For field crops, the phenomenonof allelopathy can be exploited in the form of intercropping, use ofcover crops, mulching, crop rotations, and use of plant water extracts alone orin combination with reduced doses of herbicides to provide effective controlof the agricultural pests and diseases. For the control of insect pests (field andstorage insect pests), the use of allelopathic plant water extracts and the powderof allelopathic plants may be quite useful. The allelochemicals affect thegrowth of unwanted plants (e.g., weeds) through changes in the cell structure,inhibition of cell elongation/division, disruption of membrane structures, anddisruption of water and nutrient uptake and the process of photosynthesis. Thephenomenon of allelopathy is eco-friendly, and it may help significantly reducethe usage of pesticides. Thus, the phenomenon of allelopathy provides an attractiveecological alternative to pesticides for controlling the pests and diseases ofthe agricultural crops. In this chapter, we have discussed the mechanismof allelochemicals for growth inhibition in plants and the role of crop rotation,allelopathic mulches, allelopathic cover crops, intercrops, and allelopathic waterextracts (alone or with reduced doses of herbicides) in weed management. Therole of allopathic water extracts and allelopathic powders for managing the insectpests and diseases has also been described
Developments in information security and cybernetic wars/ Muhammad Sarfraz, editor.
No full textIncludes bibliographical references and index."This book focuses on cyber warfare and terrorism using examples from around the world. It covers technical aspects, management issues, social issues, and government issues that relate to cyber warfare and terrorism"--Chapter 1. On cyber crimes and cyber security -- Chapter 2. Artificial intelligence and big data analytics in support of cyber defense -- Chapter 3. A strategic decision-making framework in cyberspace -- Chapter 4. The opportunities for a national cyber strategy and social media in the rhizome networks -- Chapter 5. Building blocks and measurement of national cyberpower -- Chapter 6. Detecting ddos attacks on multiple network hosts: advanced pattern detection method for the identification of intelligent botnet attacks -- Chapter 7. The evolution of cyber warfare in information operations targeting Estonia, the U.S., and Ukraine -- Chapter 8. The new front line (enhanced): updating the concept of enemy in the onlife age -- Chapter 9. Big data analysis for terroristic behavior identification and study using social networks: illegal armed groups during the conflict in Donbas Region (East Ukraine) -- Chapter 10. Russian information warfare and 9/11 conspiracism: when fake news meets false prophecy -- Chapter 11. The double edge of the information sword -- Chapter 12. Positive vs. negative emotions and network size: an exploratory study of twitter users.1 online resource (19 PDFs (xix, 351 pages)
Critical approaches to information retrieval research/ Muhammad Sarfraz, editor.
No full textIncludes bibliographical references and index."This book examines interdisciplinary and multidisciplinary applications in data, text, image, sound, and document retrieval"--Provided by publisher--A novel hybrid correlation measure for query expansion based information retrieval -- Uncertain confidence's network-based collaborative information retrieval relevance feedback algorithm -- Enhancing information retrieval system using change prone classes -- Search for information in text files -- An approach of documents indexing using summarization -- Building text summary generation system using universal networking language, rhetorical structure theory, sangatis and su ̄tra: summary generation using discourse structures -- Automatic ontology construction: ontology from plain text using conceptualization and semantic roles -- Emotion analysis of different age group from voice using machine learning approach -- Analysis of speaker's age using clustering approaches with emotional dependent speech features -- Some aspects of reliability estimation of loosely coupled web services in clustered load balancing web server -- Multi agent system based on data mining algorithms to detect breast cancer -- Split and merge based breast cancer segmentation and classification -- Mammogram classification using nonsubsampled contourlet transform & gray-level co-occurrence matrix -- Enhancing HE stain images through an advanced soft computing based adaptive ameliorated CLAHE: enhancing HE stain images -- Enhanced ant colony algorithm for best features selection for a decision tree classification of medical data -- Load balancing in cloud computing: challenges and management techniques.1 online resourc
Microstructural modelling of fatigue in layered bearing architectures
No full textSmall automotive plain engine bearings are used to provide the relative motion between the engine block and the crankshaft via the connecting rod. Under rapidly changing engine loads, these bearings may suffer fatigue damage during service. In modern multilayered bearing designs, fatigue resistance is a complex function of engine loading coupled with the layer architecture and a multiphase lining alloy. This research has mostly focussed upon micro-scale fatigue damage initiation on thin (0.2-0.3mm thickness) lining surface and its subsequent growth leading towards gross failure. The systems examined comprise Al alloys and sintered bronze as relatively soft and conformable lining layers. The weight percent composition of Al lining alloy was Al-6.5Sn-2.5Si-1Cu-1Ni-0.25Mn roll bonded to a stiffer and thicker backing steel layer (1.5-1.8mm thick) via an even thinner Al foil (0.04mm) as an interlayer. The other system comprised an Al lining (Al-20Sn–1Cu) alloy spray coated on to a medium carbon steel layer in the form of a flat bar. All these systems were compared with the previously investigated Al based designs with lining compositions: Al-12Sn-4Si-1Cu and Al-20Sn-1Cu-0.25Mn (manufactured by roll bonding processes). The performance evaluation was based upon the investigation of microstructural features involved in early fatigue initiation and their effect upon short crack growth on the surface. Subsurface crack growth through the layers has also been assessed and finally the observed fatigue life of various components linked to these behaviours. A 3-point bend test configuration was adopted for laboratory fatigue tests. Fatigue comparison was made on the basis of lining surface plastic strain amplitude vs. number of cycles to failure according to a uniform predefined criterion for all the systems. Maximum plastic strains developing at the lining surface were estimated using a combination of finite element analysis (FEA) and strain gauge measurements so that the fatigue life of all systems studied was presented as strain-life data. Specimens in the form of both finished bearings and flat bars were tested. Similar fatigue behaviour was observed for the two testing geometries, giving greater confidence in the fatigue evaluation process and allowing detailed observations of small crack initiation and growth processes in flat bars to be related to behaviour of the actual bearing geometry.
In the previous research, the coarser Si particles in the Al-12Sn-4Si-1Cu lining and Sn particles in the Al-20Sn-1Cu-0.25Mn alloys were identified as potential crack initiation sites, though the relationship between particle geometry and arrangement/clustering was found to be important. The newly developed Al-6.5Sn-2.5Si-1Cu-1Ni-0.25Mn lining alloy with finer and fewer Sn and Si particles showed a delayed initiation of short fatigue cracks compared to the previous systems. However, a large number of widely scattered intermetallics in the new linings were observed to fracture causing early fatigue initiation at the micro-scale level with some more complex processes of detaching Sn layers from harder intermetallics and Si particles. Using the mechanical property data for bulk lining and secondary phase particles obtained from tensile testing and instrumented hardness testing, stress fields were investigated within the hard particles (intermetallics), surrounding thin layers and the matrix on the basis of the analytical and numerical modelling. On the basis of these modelling results, optimum particle shapes were defined to minimize tensile stresses (within the particles) and hydrostatic stresses (at the particle matrix interfaces). The experimental growth data of a dominant crack when combined with a Hobson type growth model based upon measured particle distributions and experimental crack growth rates, helped in predicting fatigue life of a similar component at different stress levels. Surface crack driving force reduces considerably when subsurface crack deflection occurred within softer Al interlayer. Replacing this interlayer with a harder brazed sheet did not give any significant difference in the observed fatigue life. In the HVOF systems, crack initiation was observed to be from the weaker interface between a harder matrix and softer circular unmelts as well as from various scattered pores. The overall fatigue life of the HVOF systems was comparable to the previous roll bonded systems; however subsurface deflection of crack at the lining-backing interface resulted in the debonding of the lining and hence the observed lining fatigue resistance may not be a good indication of the overall performance in a bearing system.
At similar lining surface plastic strain levels, the bronze bearing with very thin Sn and Ni as overlay layers (~7 microns each) showed comparable fatigue resistance to the currently investigated RB Al based designs. However annealing this system resulted in the formation of hard Ni3Sn intermetallics at the Sn-Ni interface, and the observed fatigue resistance of this system was higher than the RB systems. This has been linked to very fine scale local crack deflection in the overlay layers (although these have not been observed clearly).
All these layered bearing systems provide a complex fatigue problem. Factors which reduce initiation /early growth behaviour are likely to offer the best service performance enhancements in view of the relatively HCF nature expected in service
Polyamines: natural and engineered abiotic and biotic stress tolerance in plants
No full textAbstract not availableSyed Sarfraz Hussain, Muhammad Ali, Maqbool Ahmad, Kadambot H.M. Siddiqu
Display Models for Visualization
No full textModels for visualization are important, helping the developer and user to understand the visualization process; to follow the connections and the data paths through the system; and to reference and compare the functionality and the limitations of different systems or techniques. Display models specifically classify the data by what type of output can be created. Jacques Bertin described a symbolic reference model that he used to describe images and displays. In this paper we review his and other `display orientated models' describing important aspects of these methods and ideas. We then translate Bertin's scheme into an algebraic form as a method to describe visualizations
Phytopharmacological evaluation of different solvent extract/fractions From<i> Sphaeranthus indicus</i> L. flowers:From traditional therapies to bioactive compounds
No full textSphaeranthus indicus L. is a medicinal herb having widespread traditional uses for treating common ailments. The present research work aims to explore the in-depth phytochemical composition and in vitro reactivity of six different polarity solvents (methanol, n-hexane, benzene, chloroform, ethyl acetate, and n-butanol) extracts/fractions of S. indicus flowers. The phytochemical composition was accomplished by determining total bioactive contents, HPLC-PDA polyphenolic quantification, and UHPLC-MS secondary metabolomics. The reactivity of the phenolic compounds was tested through the following biochemical assays: antioxidant (DPPH, ABTS, FRAP, CUPRAC, phosphomolybdenum, and metal chelation) and enzyme inhibition (AChE, BChE, α-glucosidase, α-amylase, urease, and tyrosinase) assays were performed. The methanol extract showed the highest values for phenolic (94.07 mg GAE/g extract) and flavonoid (78.7 mg QE/g extract) contents and was also the most active for α-glucosidase inhibition as well as radical scavenging and reducing power potential. HPLC-PDA analysis quantified rutin, naringenin, chlorogenic acid, 3-hydroxybenzoic acid, gallic acid, and epicatechin in a significant amount. UHPLC-MS analysis of methanol and ethyl acetate extracts revealed the presence of well-known phytocompounds; most of these were phenolic, flavonoid, and glycoside derivatives. The ethyl acetate fraction exhibited the highest inhibition against tyrosinase and urease, while the n-hexane fraction was most active for α-amylase. Moreover, principal component analysis highlighted the positive correlation between bioactive compounds and the tested extracts. Overall, S. indicus flower extracts were found to contain important phytochemicals, hence could be further explored to discover novel bioactive compounds that could be a valid starting point for future pharmaceutical and nutraceuticals applications.</p
STUDY REGARDING RENAL FAILURE IN KALA PATHAR POISONING
No full textDr. Abdul Basit Maqbool*, Dr. Abdullah Sarfraz Cheema, Dr. Muhammad Ahma
Dock-able linear and homodetic cyclic tri, tetra and pentapeptide library generation from all sequences of canonical amino acids
No full textHere, we provide both the complete and prefiltered libraries of all tri, tetra, and pentapeptide sequences from 20 canonical amino acids and their homodetic (N-to-C-terminal) cyclic homologues. The libraries in the FASTA, SMILES, and SDF-3D formats can be readily used for screening against protein targets. Access to this dataset will accelerate small peptide screening workflows and encourage their use in drug discovery campaigns
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