221 research outputs found
First person – Varun Jayeshkumar Shah
No full textABSTRACT
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Varun Jayeshkumar Shah is the first author on ‘CRL7SMU1 E3 ligase complex-driven H2B ubiquitination functions in sister chromatid cohesion by regulating SMC1 expression’, published in Journal of Cell Science. Varun is a PhD student in the lab of Dr Subbareddy Maddika at the Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India, investigating the role of LisH-domain-containing proteins in the assembly of multi-subunit E3 ligase complexes.</jats:p
Social rights and economics : claims to health care and education in developing countries
No full textThe author analyzes contemporary rights-based and economic approaches to health care and education in developing countries. He assesses the foundations and uses of social rights in development, outlines an economic approach to improving health and education services, and then highlights the differences, similarities, and the hard questions that the economic critique poses for rights. The author argues that the policy consequences of rights overlap considerably with a modern economic approach. Both the rights-based and the economic approaches are skeptical that electoral politics and de facto market rules provide sufficient accountability for the effective and equitable provision of health and education services, and that further intrasectoral reforms in governance, particularly those that strengthen the hand of service recipients, are needed. There remain differences between the two approaches. Whether procedures for service delivery are ends in themselves, the degree of disaggregation at which outcomes should be assessed, the consequences of long-term deprivation, metrics used for making tradeoffs, and the behavioral distortions that result from subsidies are all areas where the approaches diverge. Even here, however, the differences are not irreconcilable, and advocates of the approaches need not regard each other as antagonists.Health Monitoring&Evaluation,Health Systems Development&Reform,Decentralization,Public Health Promotion,Early Child and Children's Health,Health Monitoring&Evaluation,Health Economics&Finance,Poverty Assessment,Agricultural Knowledge&Information Systems,Gender and Education
Coherency matrices for characterization of vector optical fields
No full textWe describe optical coherency matrices as a generalized method for characterizing the statistical properties of optical fields. We then use this formalism to classify optical fields, in terms of separability, and transfer of entropy between multiple degrees of freedom.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2021-12-01The student, Varun Ajit Kelkar, accepted the attached license on 2019-07-12 at 20:22.The student, Varun Ajit Kelkar, submitted this Thesis for approval on 2019-07-12 at 20:30.This Thesis was approved for publication on 2019-07-15 at 11:29.DSpace SAF Submission Ingestion Package generated from Vireo submission #14293 on 2020-02-28 at 17:34:54Made available in DSpace on 2020-03-02T22:28:39Z (GMT). No. of bitstreams: 2
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Previous issue date: 2019-07-15Embargo set by: Seth Robbins for item 113953
Lift date: 2022-03-02T22:28:46Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 113953
Lift date: 2022-03-02T22:38:05Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 113953
Lift date: 2022-03-02T22:39:04Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 113953 on 2022-03-03T10:15:30Z
Determination of structural changes and phase transformations in boron carbide by static and dynamic studies
No full textRecent transmission electron microscopy results demonstrate that the failure of B4C is commensurate with the segregation of boron icosahedra embedded in amorphous carbon in 2–3 nm wide amorphous bands along the (113) lattice direction, in good agreement with our recent theoretical results. Boron carbide is generally composed of multiple polytypes of B4C which have the same primitive lattice parameters but differ from each other by the location of the boron and carbon atoms in the unit cells. The unit cells are formed by a 12-atom B12-nCn icosahedron and a 3-atom (C3-nBn) chain. Our theoretical results indicate that one polytype, B12(C3), whose formation is responsible for
the failure of the entire material. This anomalous and poorly understood glass-like behavior in boron carbide has been the subject of research since its discovery over 70 years ago. The characterization of disorder in hot pressed and powder boron carbide samples
is therefore of primary interest. The research work has focused on characterization techniques which can be used at a micrometric sampling size so that individual powder grains of the material can be utilized. Specifically, micro-Raman and electrical
conductivity measurements can be used with micrometric gap cells to understand the disorder in B4C.The results also demonstrate that it is possible to induce transformations in boron carbide using electric fields that are comparable with those obtained under shock and nanoindentation. Our calculations present a hypothesis which can provide a solution to prevent the
premature failure of B4C. A route to achieve suppression of the B12(CCC) polytype without significantly affecting the elastic constants is via low concentration Silicon (Si) doping of B4C. Suppression of B12(CCC) by Si doping has implications towards
development of boron carbide armor with improved properties for protection against high velocity threats. In order to achieve this, nanostructures (nanowires, nanorods, etc.) of Sidoped boron carbide have been synthesized using a Solid-Liquid-Solid (SLS) growth
mechanism. The resulting structures have been characterized by SEM, TEM and Raman
spectroscopy and consolidated to evaluate their mechanical properties. In addition, the application of nanowires in a transparent and thermally conducting nanocomposite is demonstrated.Ph.D.Includes abstractVitaIncludes bibliographical referencesby Varun Gupt
The Speaking Body: Corporeal Symbolism in Arya Gopi's Poetry
No full textPoetry is an amalgam of both melancholy and bliss for Dr. Arya Gopi. She is an Indian bilingual writer who handles a wide variety of themes, the analysis of which would perhaps be a herculean task for a scholar. Her poetry contains everything. It speaks of inner and outer conflicts. It addresses intricacies of human psyche; confronts with life and death alike. Seldom do her words wither to be of a particular theme; instead it embraces everything general. Gopi\u27s collection of poems, Sob of Strings (2016) reveals her keen observation and unique poetic techniques. Her poetry can perhaps be considered synonymous with several of the confessional poems of Sylvia Plath, Emile Dickinson and Kamala Das. Basic human emotions, life, death, nature and the like never really are redshirts here. Another significant aspect of Gopi\u27s poetry must be the vitality of corporeal imagery made use of in Sob of Strings. Body can best used in theatre rather than literature, however, systematic development of bodily symbolism can make a work of literature complete. Body plays a vital role in meaning-making, which is a complex process. Plath and Emile Dickinson have constantly made use of several body centred symbols in order to depict intricacies of the human psyche. So does the author of Sob of Strings. Her poetry thus is a celebration of versatile themes, to justify which the author, without deliberate interruption, uses a handful of corporeal symbols
The Need for Continued Innovation in Solar, Wind, and Energy Storage
No full textVarun Sivaram is the Philip D. Reed fellow for science and technology at the Council on Foreign Relations. He is also an adjunct professor at Georgetown University, an adjunct senior research scholar at Columbia University, and a member of the energy and environment advisory boards at Stanford University. He is the author of the book, Taming the Sun: Innovations to Harness Solar Energy and Power the Planet (MIT University Press, 2018) and the editor of the book, Digital Decarbonization: Promoting Clean Energy Systems Through Digital Innovations (CFR Press, 2018). Forbes named him one of its 30 under 30 in law and policy, and Grist named him one of the top 50 leaders in sustainability
Efficient parallel processing and fault tolerance in a streaming join system
No full textThesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2018.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (pages 91-92).Stream joins are an important component of stream processing, as they provide an online mechanism to efficiently combine multiple streams of data. In this thesis, we consider the RiverJoin system, which presents a general method for performing stream joins without relying on the ordering and timing of records in a stream. RiverJoin implements a useful set of primitives, called operands, that provide persistence and caching, allowing full-history stream joins. RiverJoin implements critical performance optimizations like batching and automatic parallelization, having performance comparable to lossy windowed joins while maintaining its strong correctness semantics. The individual contributions of the thesis come from further extending RiverJoin by adding functionality required for an end-to-end distributed system, specifically sharding and fault tolerance. In particular, we are able to leverage RiverJoin's automatic parallelization mechanism to provide a data stream sharding interface that allows for close-to linear speedup in stream joins, allowing arbitrarily fast joins. Stream processing systems require high throughput and low latency in order to provide real-time guarantees. Traditional methods of periodic global snapshots provide fault recovery at the cost of pausing the entire system during the snapshot process and persisting records in transit, leading to large snapshot sizes. In this thesis, we present a low-latency mechanism to snapshot a RiverJoin topology asynchronously, providing consistent system recovery and exactly-once delivery semantics between its operands. The method builds upon the idea of Asynchronous Barrier Snapshotting (ABS) and a novel asynchronous backup strategy, called fork-backup, that can snapshot an operand with gigabytes of state in milliseconds. Our results show that we can take snapshots without affecting system latency and throughput even with frequent snapshotting. We are also able to issue and complete a global snapshot for a complex RiverJoin topology in around 50ms, faster than a Java GC pause, and can recover from failure in less than a second.by Varun Mohan.M. Eng
Key Leaders’ Opinion on Peri-Operative Risk Factor and Therapeutic Strategy in Lung Cancer Surgery
No full textPerioperative care remains a hot and controversial issue to thoracic surgeons with their multidisciplinary teams in the current clinical practice of lung cancer surgery. A better understanding regarding a series of effective and simple risk factors will provide significant assistance to identify which patients should be considered at high surgical risk. Subsequently, an accurate and personalized treatment scheme based on these putative prognostic factors will be vital to prevent the morbidity risk, enhance the surgical tolerability, and limit the unfavorable survival. Each contributing author has a particular interest in the selected hot subjects of modern perioperative medicine in lung cancer surgery, including body composition, host immune-nutritional status, tumor spread through air spaces (STAS), conversion to thoracotomy, enhanced recovery after surgery (ERAS), elderly health care, protective ventilation, intraoperative fluid management, digital pleural drainage technology, lung ultrasonography, endoscopic intervention, etc. They have given their influential opinions by literature review, personal expertise, and outcome discussion from their works. In this way, this book can help the readers get a comprehensive scenario about the current research highlights of perioperative risk factor analysis and appropriate treatment options in lung cancer surger
Modeling of a magneto-rheological (MR) damper using genetic programming
No full textThis paper is based on the experimental study for design and control of vibrations in automotive vehicles. The objective of this paper is to develop a model for the highly nonlinear Magneto-Rheological (MR) damper to maximize passenger comfort in an automotive vehicle. The behavior of the MR damper is studied under different loading conditions and current values in the system. The input and output parameters of the system are used as a training data to develop a suitable model using Genetic Algorithm. To generate the training data, a test rig similar to a quarter car model was fabricated to load the MR damper with a mechanical shaker to excite it externally. With the help of the test rig the input and output parameter data points are acquired by measuring the acceleration and force of the system at different points with the help of an impedance head and accelerometers. The model is validated by measuring the error for the testing and validation data points. The output of the model is the optimum current that is supplied to the MR Damper, using a controller, to increase the passenger comfort by minimizing the amplitude of vibrations transmitted to the passenger. Besides using this model for cars, bikes and other automotive vehicles it can also be modified by re-training the algorithm and used for civil structures to make them earthquake resistant.Published versio
Why is unemployment so high in Bulgaria?
No full textThe author seeks to determine the main factors behind poor labor market outcomes in Bulgaria. Unemployment in Bulgaria is high and of long duration. The accumulation of the unemployment stock has been caused by relatively high inflows into unemployment coupled with limited outflows. These features of the Bulgarian labor market are typical of other transition economies in Central Europe and exploring their sources is of broad interest. The author focuses on determinants of and constraints to job creation. He uses data on job creation and job destruction from a survey of employment in all registered firms. He finds that the source of large inflows into unemployment is intensive enterprise restructuring associated with a high pace of job reallocation. However, job creation falls short of job destruction. Three main factors account for the limited job creation and hiring, and thus for low outflows from unemployment: a) The unfriendly business environment, reflected by a low rate of new firm formation, and a relatively small, small and medium enterprise sector. b) Labor market rigidities, including excessive hiring and firing costs. c) Skill and spatial mismatches brought about by enterprise restructuring, as well as low skills and marginalization of the long-term unemployed who cannot successfully compete for new jobs. The author recommends a three pronged strategy to improve labor market performance: (1) removing bureaucratic constraints to entry and expansion of firms; (2) enhancing labor market flexibility through lowering hiring and firing costs; and (3) improving the educational system so as to equip workers with broad and portable skills.Environmental Economics&Policies,Labor Policies,Labor Markets,Public Health Promotion,Health Monitoring&Evaluation,Environmental Economics&Policies,Labor Markets,Health Monitoring&Evaluation,Labor Standards,Banks&Banking Reform
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