1,721,357 research outputs found
Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft
No full textStern I, Schaschke N, Moroder L, Turk D. Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft. BIOCHEMICAL JOURNAL. 2004;381(2):511-517
Conformational and molecular modeling studies of beta-cyclodextrin-heptagastrin and the third extracellular loop of the cholecystokinin 2 receptor
No full textGiragossian C, Schaschke N, Moroder L, Mierke DF. Conformational and molecular modeling studies of beta-cyclodextrin-heptagastrin and the third extracellular loop of the cholecystokinin 2 receptor. BIOCHEMISTRY. 2004;43(10):2724-2731
E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl group
No full textSchaschke N, AssfalgMachleidt I, Machleidt W, Turk D, Moroder L. E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl group. BIOORGANIC & MEDICINAL CHEMISTRY. 1997;5(9):1789-1797
beta-cyclodextrin/epoxysuccinyl peptide conjugates: new drug targeting system for tumor cells
No full textSchaschke N, Assfalg-Machleidt I, Machleidt W, Lassleben T, Sommerhoff CP, Moroder L. beta-cyclodextrin/epoxysuccinyl peptide conjugates: new drug targeting system for tumor cells. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2000;10(7):677-680
Oligopresentation of protease inhibitors with beta-cyclodextrin as template
No full textSchaschke N, Musiol HJ, AssfalgMachleidt I, Machleidt W, Moroder L. Oligopresentation of protease inhibitors with beta-cyclodextrin as template. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 1997;7(19):2507-2512
Interaction of metal ions with gastrointestinal hormones: binding studies of Mg++ to biologically active analogs of little gastrin and minigastrin.
No full text
Cyclodextrins as templates for the presentation of protease inhibitors
No full textSchaschke N, Musiol HJ, AssfalgMachleidt I, Machleidt W, RudolphBohner S, Moroder L. Cyclodextrins as templates for the presentation of protease inhibitors. FEBS LETTERS. 1996;391(3):297-301
Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors
No full textSchaschke N, Assfalg-Machleidt I, Machleidt W, Moroder L. Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors. FEBS LETTERS. 1998;421(1):80-82
Primed-site probing of papain-like cysteine proteases
No full textPfizer JM, Assfalg-Machleidt I, Machleidt W, Moroder L, Schaschke N. Primed-site probing of papain-like cysteine proteases. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 2007;13(1-2):93-104
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