222,073 research outputs found
La libertà umana. Storia di una controversia filosofica
No full textSaggi di M. De Caro, L. Fonnesu, G. Lettieri, M. Mori, C. Natali, P. Porro, E. Spinelli, F. Trabatton
Characterisation of Bombyx mori odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components
Get PDFIn many insect species, odorant-binding proteins (OBPs) are thought to be responsible for the transport of pheromones and other semiochemicals across the sensillum lymph to the olfactory receptors (ORs) within the antennal sensilla. In the silkworm Bombyx mori, the OBPs are subdivided into three main subfamilies; pheromone-binding proteins (PBPs), general odorant-binding proteins (GOBPs) and antennal-binding proteins (ABPs). We used the MotifSearch algorithm to search for genes encoding putative OBPs in B. mori and found 13, many fewer than are found in the genomes of fruit flies and mosquitoes. The 13 genes include seven new ABP-like OBPs as well as the previously identified PBPs (three), GOBPs (two) and ABPx. Quantitative examination of transcript levels showed that BmorPBP1, BmorGOBP1, BmorGOBP2 and BmorABPx are expressed at very high levels in the antennae and so could be involved in olfaction. A new two-phase binding assay, along with other established assays, showed that BmorPBP1, BmorPBP2, BmorGOBP2 and BmorABPx all bind to the B. mori sex pheromone component (10E,12Z)-hexadecadien-1-ol (bombykol). BmorPBP1, BmorPBP2 and BmorABPx also bind the pheromone component (10E,12Z)-hexadecadienal (bombykal) equally well, whereas BmorGOBP2 can discriminate between bombykol and bombykal. X-ray structures show that when bombykol is bound to BmorGOBP2 it adopts a different conformation from that found when it binds to BmorPBP1. Binding to BmorGOBP2 involves hydrogen bonding to Arg110 rather than to Ser56 as found for BmorPBP1
Redevelopment after the Abruzzo event
Get PDFNatural disasters raise quite a number of interdisciplinary issues concerning regional economic growth and local development, as well as public finance and sustainability, to mention only a few of them. These issues deserve special attention in our globalized world, given the expectation of a growing impact of climate-related disasters: no surprise that disaster management stands as a new discipline aimed at bridging the gap between theory and practice, so as to prevent natural disasters in the first place; afterwards, considerable efforts are required to accelerate business recovery, quickly restore vital energies, and hopefully carry out specific improvement projects as a sort of compensation for the (both personal and economic) losses suffered. Interesting lessons can be learned from natural disasters and can be shared as a payback to those who helped upon their occurrence. Actually, cooperation calls for cross-cultural activities that are likely to benefit from direct experience made by impacted scholars and practitioners: a case in point has to do with the earthquake that devastated L’Aquila and its environs on April 6, 2009 causing more than 300 deaths, apart from extensive damage in the Abruzzo region, in Central Italy; the Abruzzo event – as this natural disaster is currently referred to – fuels the debate on redevelopment problems to be faced under similar circumstances, that may obliterate the economic environment and attractiveness of an area in a few moments. Due to the huge amount of money needed to undertake appropriate strategies, finance plays a key role and useful insights can be gained by exploring the process of financial innovation. A supporting argument deals with the recourse to micro-finance in order to make the business and economic scenario revive after a natural disaster: micro-credit might be resorted to even within the framework of new financial engineering instruments, such as Urban Development Funds, recently promoted by the European Investment Bank; they include JESSICA (Joint European Support for Sustainable Investment in City Areas) and JEREMIE (Joint European Resources for Micro to Medium Enterprises), to be properly considered as strategic tools in sight of redeveloping L’Aquila and its surrounding boroughs.
Improved performance of submicrometer-gate GaAs MESFET's with an Al0.3Ga0.7As buffer layer grown by metal organic vapor phase epitaxy
No full textJiro Mori at Fort Snelling [04]
No full textBlack and white photograph of Jiro Mori and another Japanese American soldier at Fort Snelling, Minnesota, during World War II
Jiro Mori at Fort Snelling [07]
No full textBlack and white photograph of Jiro Mori and another Japanese American soldier at Fort Snelling, Minnesota, during World War II
Jiro Mori at Fort Snelling [03]
No full textBlack and white photograph of a Japanese American soldier (probably Jiro Mori) at Fort Snelling, Minnesota, during World War II
Jiro Mori at Fort Snelling [08]
No full textBlack and white photograph of Jiro Mori and another Japanese American soldier at Fort Snelling, Minnesota, during World War II
Jiro Mori at Fort Snelling [05]
No full textBlack and white photograph of a Japanese American soldier (probably Jiro Mori) at Fort Snelling, Minnesota, during World War II
Jiro Mori at Fort Snelling [02]
No full textBlack and white photograph of Japanese American soldiers, including Jiro Mori, marching at Fort Snelling, Minnesota, during World War II
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