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Re: "Deep Anterior Lamellar Keratoplasty in Eyes With Intrastromal Corneal Ring Segments"
xletter to edito
Ab interno intraluminal suture to reverse ocular hypotony after glaucoma drainage device implantation
Herein
we would like to report our experience using the same
technique to treat hypotony after Baerveldt valve implantation
Ab interno intraluminal suture to reverse ocular hypotony after glaucoma drainage device implantation
This letter describes our experience in treating glaucoma valve induced ocular hypotony using a minimally invasive ab interno approac
Descemet stripping only in Fuchs’ endothelial dystrophy without use of topical Rho-kinase inhibitors: 5-year follow-up
Objective: To describe 5-year postoperative outcomes of a small series of Fuchs' endothelial dystrophy (FED) patients who underwent Descemet stripping only (DSO) with a scraping technique.
Methods: DSO technique and early clinical outcomes of 5 patients with mild central FED were previously reported. In the same cohort of patients, corrected distance visual acuity, central corneal ultrasound pachymetry, refractive spherical equivalent, endothelial cell count, slit-lamp photography, and corneal Scheimpflug tomography were obtained at baseline, 6 months, and 1 and 5 years postoperatively. No patient used topical Rho-kinase inhibitors at any point in time.
Results: One patient (20%) failed to clear the early postoperative edema and 1 patient (20%) developed corneal decompensation 1 year after DSO. Both patients underwent successful Descemet stripping automated endothelial keratoplasty. The remaining 3 patients had stable corrected distance visual acuity, progressive reduction of corneal ultrasound pachymetry, and mild myopic shift of the refractive spherical equivalent over the follow-up time. An improvement in posterior stromal opacities and irregular astigmatism was observed, whereas posterior elevation at Scheimpflug tomography remained unchanged.
Conclusion: At 5 years postoperatively, DSO with a scraping technique and without Rho-kinase inhibitors resulted in sustained clinical amelioration of 3 of 5 patients (60%) with mild FED
Fattori di rischio protrombotici nei pazienti con neuropatia ottica ischemica anteriore non arteritica.
Ab interno intraluminal suture to reverse ocular hypotony after glaucoma drainage device implantation
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In the manuscript titled “Management of Descemet's Membrane Folds after Deep Anterior Lamellar Keratoplasty: Descemet Membrane—Tucking Technique,” we described a simple technique to displace the graft periphery Descemet membrane (DM) folds when present at the end of the procedure. We agree with Nagpal et al that the occurrence of this complication is relatively rare and more frequently seen in cases of keratoconus with severe corneal ectasia (central mean Ks ≥ 60 D). DM folds may occur after big-bubble Deep Anterior Lamellar Keratoplasty (DALK) regardless of the type of bubble achieved (type 1 or 2), and they typically present as fine folds with linear or curvilinear circumferential orientation (Fig. 1). As correctly mentioned by the authors of this letter, DM folds may be the cause of visual disturbances for the patients particularly at night while driving. We have observed that DM folds, when present, should be corrected as soon as seen in the postoperative period, whenever they involve the central 4-mm visual axis. Surgical correction using the technique we suggested should take place within 1 month after surgery because after 1 month, the DM folds tend to remain despite efforts to correct them. Among the 16 cases reported, none of the patients developed recurrence of folds in the central visual axis after 6 months of follow-up or more. As we mentioned in the study, after the DM–tucking technique, DM folds in the peripheral graft–host interface often remain visible, but they do not cause visual disturbances.
The DM–tucking technique should be carried out using a blunt tip spatula by gently pressing on the host membrane. In the case of type 1 bubble formation, this membrane is fairly resistant and the risk of membrane tearing is low because it never occurred in the patients reported. We mentioned that in the case of bubble 2 formation, the risk of tearing is greater and the maneuver should be conducted with great caution. However, should a DM tear occur, this should remain in the periphery and fairly easily managed by injecting an air bubble in the anterior chamber in case of double anterior chamber formatio
Analisi dei glicopatterns dell’involucro ovulare di Pelophylax sp. della Gravina di Laterza (TA)
Interface infectious keratitis after anterior and posterior lamellar keratoplasty. Clinical features and treatment strategies. A review
Interface infectious keratitis (IIK) is a novel corneal infection that may develop after any type of lamellar keratoplasty. Onset of infection occurs in the virtual space between the graft and the host where it may remain localised until spreading with possible risk of endophthalmitis. A literature review identified 42 cases of IIK. Thirty-one of them occurred after endothelial keratoplasty and 12 after deep anterior lamellar keratoplasty. Fungi in the form of Candida species were the most common microorganisms involved, with donor to host transmission of infection documented in the majority of cases. Donor rim cultures were useful to address the infectious microorganisms within few days after surgery. Due to the sequestered site of infection, medical treatment, using both topical and systemic antimicrobials drugs, was ineffective on halting the progression of the infection. Injection of antifungals, right at the graft-host interface, was reported successful in some cases. Spreading of the infection with development of endophthalmitis occurred in five cases after Descemet stripping automated endothelial keratoplasty with severe sight loss in three cases. Early excisional penetrating keratoplasty showed to be the treatment with the highest therapeutic efficacy, lowest rate of complications and greater visual outcomes
Comment on: Vitrectomy in Small idiopathic MAcuLar hoLe (SMALL) study: conventional internal limiting membrane peeling versus inverted flap
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