19 research outputs found
Data from: A study on the Influence of submergence ratio on the transportation of suspended sediment in a partially vegetated channel flow
No full textRiparian or aquatic vegetation thrives with seasons. The understanding of canopies' Submergence-Ratio SR (stems' height to water depth) influence on suspended sediments' transportation is still limited. Thus, Large Eddy Simulations (LES) coupled with the Discrete Phase Method (DPM) are used to investigate the particles' 3-dimensional distribution in a partially vegetated straight channel. The spanwise distribution of particles is quantified by the Probability Density Function (PDF), showing a non-uniformity of particles in time as quantified by the PDF variance. The findings and conclusions: (Ⅰ) With SR rising, the particles' depletion effects exerted by the vegetation-side mixing layer are improved along the interface between vegetated and vegetation-side bare channel region. However, the SR has little effect on the variance of the particles' PDF in the spanwise direction when the mixing layer is fully developed. (Ⅱ) During the developing stage of the over-canopy mixing layer, submerged vegetation with higher SR gain a stronger upwards (vertical) entrainment capability. The case (SR=60%) has a higher sediment concentration than other cases in the fully developed vertical mixing layer region above canopy. (III) The vertical suspension of particles in the vegetation-side bare channel region is analysed. Particles migrating from the vegetated region are entrained into the vegetation-side bare channel region by turbulent structures. Nevertheless, the vertical concentration profile is more uniform in the vegetated region than in the vegetation-side bare channel at the same streamwise location. The cases SR=40% and 60% still have higher sediment concentrations than other cases in the vegetation-side bare channel's upper region.The corresponding author is Dr. Eldad Avital. Mingyang Wang is the first author. Funding provided by: Engineering and Physical Sciences Research CouncilCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100000266Award Number:The datasets are produced mainly based on the numerical simulations, some exprimental data is collected from published literatures
How Do We Remember the Armenian Genocide and the Holocaust? A Global View of an Integrated Memory of Perpetrators, Victims and Third-Party Countries
No full textWhile acknowledgement that the Holocaust took place has become a distinct aspect of Western culture, the genocide against the Armenians is still denied by many states and a culture of memorialisation is missing. What drives these divergent trends in Holocaust and Armenian genocide memory? And why is there such a significant difference in the way in which these two genocides have been represented in the public, political and international arena by the perpetrators, victims and third-party countries? The author presents answers and causes and concludes with recommendations for current domestic and foreign policy
The Said and the Unsaid: Performative Guiding in a Jerusalem Neighborhood
No full textThis paper describes a guided walking tour of a formerly Palestinian neighbourhood in Jerusalem and an important battlefield in the 1948 Arab—Israeli War.The paper assumes a critical performance approach to guided tours in examining how through performative guiding, identities, histories and places are (re)constituted. We conceive of performative guiding as a situated event which both takes place in and simultaneously signifies and reconstructs the environment wherein it transpires. The tour we analyse was given by a Jewish-Israeli guide to a Jewish-Israeli audience, and was attended by the first author. The guide’s apparent inclination towards the Israeli and Zionist narrative regarding the story of the neighbourhood is highlighted through an analysis of the commentary given. Through an examination of things said and unsaid, we highlight the dual role of performative guiding: relaying historical information and reaffirming partisan narratives
Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimers as HIV-1 vaccine candidates
No full textAbstract Uncleaved prefusion-optimized (UFO) design can stabilize diverse HIV-1 envelope glycoproteins (Envs). Single-component, self-assembling protein nanoparticles (1c-SApNP) can display 8 or 20 native-like Env trimers as vaccine candidates. We characterize the biophysical, structural, and antigenic properties of 1c-SApNPs that present the BG505 UFO trimer with wildtype and modified glycans. For 1c-SApNPs, glycan trimming improves recognition of the CD4 binding site without affecting broadly neutralizing antibodies (bNAbs) to major glycan epitopes. In mice, rabbits, and nonhuman primates, glycan trimming increases the frequency of vaccine responders (FVR) and steers antibody responses away from immunodominant glycan holes and glycan patches. The mechanism of vaccine-induced immunity is examined in mice. Compared with the UFO trimer, the multilayered E2p and I3-01v9 1c-SApNPs show 420 times longer retention in lymph node follicles, 20-32 times greater presentation on follicular dendritic cell dendrites, and up-to-4 times stronger germinal center reactions. These findings can inform future HIV-1 vaccine development
Numerical investigation of particle saltation in the bed-load regime
No full textThis work was supported by a Marie Curie International Incoming Fellowship
within the seventh European Community Framework Programme
(Grant No. PIIF-GA-2009-236457). The first author acknowledges the
financial support of the Science Fund for Creative Research Groups of the
National Natural Science Foundation of China (Grant No. 51321065),
Programme of Introducing Talents of Discipline to Universities (Grant No.
B14012), National Natural Science Foundation of China (Grant Nos.
50809047 and 51009105) and Natural Science Foundation of Tianjin
(Grant No. 12JCQNJC02600). We thank UKTC for HECToR computer time
and facilities.Publisher PDF not permitted - withdraw
The ideological and the dialogical
No full textHaye A, Carvacho H, Larraín A. The ideological and the dialogical. Journal für Psychologie. 2011;19(1).In this paper we follow researchers on ideology in that one way of dealing with this problem is by conceiving language as a common ground between the social and the psychological, and then we focus on Bakhtin's theory of discourse to show how language practices can be regarded as the locus of ideology. We will approach the Bakhtinian concepts of discourse and utterance, showing the ideological nature of language practices in three steps. First, because language practices consist of position-taking movements in a social field. Second, because these acts of discourse are evaluations, that is, value-laden positioning effort. And finally because any utterance involves a social background that roots the evaluative positioning movement in a history of language practices common among speaking subjects. Then we explore this third aspect in terms of the common social life that is discursively assumed in communication and thinking activity
Computational methods for investigation of surface curvature effects on airfoil boundary layer behavior
No full textThis article presents computational algorithms for the design, analysis, and optimization of airfoil aerodynamic performance. The prescribed surface curvature distribution blade design (CIRCLE) method is applied to a symmetrical airfoil NACA0012 and a non-symmetrical airfoil E387 to remove their surface curvature and slope-of-curvature discontinuities. Computational fluid dynamics analysis is used to investigate the effects of curvature distribution on aerodynamic performance of the original and modified airfoils. An inviscid–viscid interaction scheme is introduced to predict the positions of laminar separation bubbles. The results are compared with experimental data obtained from tests on the original airfoil geometry. The computed aerodynamic advantages of the modified airfoils are analyzed in different operating conditions. The leading edge singularity of NACA0012 is removed and it is shown that the surface curvature discontinuity affects aerodynamic performance near the stalling angle of attack. The discontinuous slope-of-curvature distribution of E387 results in a larger laminar separation bubble at lower angles of attack and lower Reynolds numbers. It also affects the inherent performance of the airfoil at higher Reynolds numbers. It is shown that at relatively high angles of attack, a continuous slope-of-curvature distribution reduces the skin friction by suppressing both laminar and turbulent separation, and by delaying laminar-turbulent transition. It is concluded that the surface curvature distribution has significant effects on the boundary layer behavior and consequently an improved curvature distribution will lead to higher aerodynamic efficiencyThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The PhD research of Xiang Shen is funded by China Scholarship Council (CSC)/Queen Mary Joint PhD scholarship
The benefits, challenges, and best practice for patient and public involvement in evidence synthesis: A systematic review and thematic synthesis
No full textAbstract Introduction Despite the growing evidence on patient and public involvement (PPI) in health research, little emphasis has been placed on understanding its quality and appropriateness to evidence synthesis (ES) and systematic reviews (SR). This study aimed to synthesise qualitative evidence on the benefits, challenges, and best practices for PPI in ES/SR projects from the perspectives of patients/public and researchers. Methods We searched Ovid MEDLINE, Ovid EMBASE, Cochrane Library and CINAHL Plus. We also searched relevant grey literature and conducted hand‐searching to identify qualitative studies which report the benefits and challenges of PPI in individual ES/SR projects. Studies were independently screened by two reviewers for inclusion and appraised using the Joanna Briggs Institute's Qualitative Tool. Included studies were synthesised narratively using thematic synthesis. Results The literature search retrieved 9923 articles, of which eight studies were included in this review. Five themes on benefits emerged: two from patients'/public's perspective—gaining knowledge, and empowerment; and three from researchers' perspective—enhancing relevance, improving quality, and enhancing dissemination of findings. Six themes on challenges were identified: three from patients'/public's perspective—poor communication, time and low self‐esteem; and three from researchers' perspective—balancing inputs and managing relations, time, and resources and training. Concerning recommendations for best practice, four themes emerged: provision of sufficient time and resources, developing a clear recruitment plan, provision of sufficient training and support, and the need to foster positive working relationships. Conclusion Highlighting the benefits and challenges of PPI in ES/SR projects from different stakeholder perspectives is essential to understand the process and contextual factors and facilitate meaningful PPI in ES/SR projects. Future research should focus on the utilisation of existing frameworks (e.g., Authors and Consumers Together Impacting on eVidencE [ACTIVE] framework) by researchers to help describe and/or report the best approaches and methods for involving patients/public in ES/SRs projects. Patient and Public Contribution This review received great contributions from a recognised PPI partner, the Chair of the Cochrane Consumer Network Executive, to inform the final stage of the review (i.e., interpretation, publication and dissemination of findings). The PPI partner has been included as an author of this review
