272,432 research outputs found
Will Rogers State Beach, Santa Monica, Calif.
No full textSanta Monica Public Library Image Archives.
C213
1956 img0056
Elliott Welsh Collection
Frailty multi-state models for the analysis of survival data from multicenter clinical trials
No full textProportional hazards models are among the most popular regression models in survival analysis. Multi-state models generalise them in the sense of jointly considering different types of events along with their interrelations, whereas frailty models introduce random effects to account for unobserved risk factors, possibly shared by groups of subjects.
The integration of frailty and multi-state methodology is interesting to control for unobserved heterogeneity in presence of complex event history structures, particularly appealing in multicenter clinical trials applications.
In the present thesis we propose the incorporation of nested frailties in the transition-specific hazard function; then, we develop and evaluate both parametric and semi-parametric inference. Simulation studies, performed thanks to an innovative method for generating dependent multi-state survival data, show that parametric inference is correct but extremely imprecise, whilst semiparametric methods are very competitive to evaluate the effect of covariates.
Two case studies are presented, relative to cancer multicenter clinical trials. The multi-state nature of the models allows to study the treatment effect taking into account intermediate events, while the presence of frailties reduces the attenuation effect due to clustering.
Finally, we present two new software tools, one to fit parametric frailty models
with up to twenty possible combinations of baseline and frailty distributions, and one implementing semiparametric inference for multilevel frailty models, essential to fit the new nested frailty multi-state models
Oral history interview with Monica Chavez
No full textMonica Chavez, born in Oklahoma to Mexican immigrant parents, enrolled in Oklahoma State University (OSU) in 2015 and is the first generation in her family to go to college. She shares what it is like to be a minority student and mentions some of the people and programs that have provided support, including the Retention Initiative for Student Excellence (RISE). Chavez explains her continued interest and work in the League of United Latin American Citizens and her goal of showing minority students that they do have a place at OSU. She hopes to leave OSU having made a difference for future Hispanic students. This is part of the Latino Americans: 500 Years of History project.The O-STATE Stories Oral History collection is comprised of interviews which chronicle the rich history, heritage, and traditions of Oklahoma State University
Will Rogers State Beach, Santa Monica, Calif.
No full textSanta Monica Public Library Image Archives.
C212
1956 img0055
Elliott Welsh Collection
New Electronic State Documents List - April 2024
No full textThe monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository. Included is the title, author and/or agency, description, thumbnail, link to access full-text file, and OCLC number
New electronic state documents list - March 2024
No full textThe monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository. Included is the title, author and/or agency, description, thumbnail, link to access full-text file, and OCLC number
New electronic state documents list - November 2023
No full textThe monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository. Included is the title, author and/or agency, description, thumbnail, link to access full-text file, and OCLC number
New electronic state documents list - October 2023
No full textThe monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository. Included is the title, author and/or agency, description, thumbnail, link to access full-text file, and OCLC number
New electronic state documents list -February 2024
No full textThe monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository. Included is the title, author and/or agency, description, thumbnail, link to access full-text file, and OCLC number
New electronic state documents list - January 2024
No full textThe monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository. Included is the title, author and/or agency, description, thumbnail, link to access full-text file, and OCLC number
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