126 research outputs found
Nathan Perlmutter (1923-1987) papers, 1934-1989, 1949-1987.
No full textThis collection consists of the papers of Nathan Perlmutter, a lawyer, lecturer, author, political activist, and a long-time leader of the American Jewish community. It contains certificates, newspaper clippings, correspondence—including numerous condolence cards and letters sent to his family after his death—manuscripts and drafts of Perlmutter’s writings, obituaries, printed materials, programs, and subject files relating to topics he was interested in and that he wrote about.Published citations should take the following form: Identification of item, date (if known); Nathan Perlmutter (1923-1987) Papers; P-1012; box number; folder number; American Jewish Historical Society, New York, NY, and Boston, MA.Donated by Ruth Ann Perlmutter
Identifying Communication Behaviors That Promote Interprofessional Teamwork Among Health Care Profession Students
No full textAbstract
Date Presented 4/1/2017
The purpose of this study was to identify communication behaviors of students on an interprofessional team that impact patient and team satisfaction. Findings can be used to develop interprofessional educational experiences designed to foster team performance and quality of care.
Primary Author and Speaker: Monica Perlmutter
Additional Authors and Speakers: Susan Tucker
Contributing Authors: Dehra Harris, Gloria R. Grice</jats:p
From Paralysis to Progress: The (Useful) Art of Copyright Pragmatism
No full textAmericans want the nation’s copyright laws to make sense, be fair, and reflect the technologies in use, argued Shira Perlmutter, chief policy officer and director for international affairs, United States Patent and Trademark Office. Her April 15 lecture at Catholic University’s law school noted that for some reason, Congress and regulatory oversight bodies have historically had a hard time meeting that reasonable expectation. Her remarks were presented as the 2014 Dean William Callyhan Robinson Intellectual Property Lecture, a series named after the author the founding dean of the law school at The Catholic University of America
Rethinking the value of initial claims as a forecasting tool
No full textThe weekly numbers on initial claims for unemployment insurance convey key information about the labor market. But how reliable are claims in predicting changes in the much anticipated monthly employment report? According to a simple forecasting model, claims consistently send an accurate signal about employment during recessions but not during expansions.Unemployment insurance ; Forecasting ; Employment (Economic theory)
The influence of positively charged nitrogen species on compound accumulation and activity in gram-negative bacteria
No full textMultidrug resistant Gram-negative bacterial infections are on the rise, and with no FDA approvals for new classes of broad-spectrum antibiotics in over 50 years, these infections constitute a major threat to human health. A significant challenge is the inability of most compounds to accumulate in Gram-negative bacteria. Recently developed predictive guidelines called the eNTRy rules show that appending a primary amine to an appropriately shaped compound can enhance Gram-negative accumulation and antibacterial activity. However, in certain cases addition of a primary amine resulted in the disruption of target engagement. Therefore, it would be advantageous to have alternate functional groups that facilitate accumulation in Gram-negative bacteria but offer different interactions with a given target protein.
Here we report that other positively charged nitrogen functional groups, namely N-alkyl guanidiniums and pyridiniums, can also facilitate compound uptake into Gram-negative bacteria. Accumulation of a set of 60 non-antibiotic compounds, consisting of 20 primary amines derived from the Complexity-to-Diversity strategy and their corresponding guanidiniums and pyridiniums, was assessed in Escherichia coli. We also installed these alternate functional groups onto six antibiotic scaffolds and assessed their accumulation and antibacterial activity in Gram-negative bacteria. In addition, computational studies were performed to predict whether additional charged functional groups will be able to facilitate Gram-negative uptake. The results suggest that other positively charged, nitrogen-containing functional groups should be considered when designing antibiotics with Gram-negative activity.
Finally, retrospective analysis of commercial screening libraries showed a lack of compounds containing primary amines. This is likely a major reason for the failures within the pharmaceutical industry to find lead compounds with whole cell activity from high throughput screening campaigns. Here strategies for addressing this problem through efficient amine installation strategies are discussed and applied to compounds from the CtD collection and their antimicrobial activity assessed.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2022-12-01The student, Sarah Perlmutter, accepted the attached license on 2020-11-23 at 12:13.The student, Sarah Perlmutter, submitted this Dissertation for approval on 2020-11-23 at 13:00.This Dissertation was approved for publication on 2020-11-25 at 11:56.DSpace SAF Submission Ingestion Package generated from Vireo submission #15939 on 2021-03-04 at 16:19:47Made available in DSpace on 2021-03-05T21:42:39Z (GMT). No. of bitstreams: 7
PERLMUTTER-DISSERTATION-2020.pdf: 11225845 bytes, checksum: 9810632d9c7da9ee5f73a4aa998df3f0 (MD5)
6-azaindazole crystal structure reuse permission_Rightslink? by Copyright Clearance Center.pdf: 97166 bytes, checksum: 25e3ee512661cb3887fdcb078aaffa6a (MD5)
LICENSE.txt: 4213 bytes, checksum: 5fcd01b4543a44d02f0e4102c8fa7369 (MD5)
PROQUEST_LICENSE.txt: 4559 bytes, checksum: 9618ea9e0e9d1a1fc8b436ab086e521c (MD5)
RightsLink Printable License.pdf: 179037 bytes, checksum: 8e6eec5bd1ff3644ba847d2fc05b858a (MD5)
RightsLink Printable License2.pdf: 178961 bytes, checksum: 9e17ca481e7693ad01ec0469071ee2c5 (MD5)
bd2acec0-2a8e-443e-a43d-2ac9c510481a.pdf: 55989 bytes, checksum: 6cbc99996aa0bd88bc0a0248929ccfd4 (MD5)
Previous issue date: 2020-11-25Embargo set by: Seth Robbins for item 117210
Lift date: 2023-03-05T21:43:00Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemAuthor requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Onl
A Community Based Experience to Enhance Occupational Therapy Student Clinical Skills with Clients with Mental Illness
No full textDespite the high number of individuals living with severe mental illness and the evidence to support effective interventions, only a small percentage of occupational therapy practitioners work in community mental health settings. To address the need for more occupational therapists in this area of practice, schools must provide educational experiences that facilitate interactions with individuals experiencing severe mental illness to increase students’ competence with this population. The Washington University Program in Occupational Therapy fosters students’ clinical reasoning skills throughout a two semester case-based learning course. For the community mental health module at the end of the 2nd semester, the program partnered with two local community agencies to provide an opportunity for students to work with clients experiencing severe mental illness. Students administered assessments, planned and implemented interventions, and completed documentation. Following the experience, students reported increased ability to facilitate interventions and adapt to client needs and clients reported an increase in independent living skills. This paper will describe the development of the course module, collaboration between the academic institution and community based agencies, and student learning outcomes and feedback. A case study illustrates the benefits for one client participant
Stereoselective intermolecular oxymercurations of allylic ethers.
No full textThe influence of alkene geometry and allylic substitution on the stereochemical outcome of intermolecular oxymercurations of allylic ethers is described. (C) 1997 Published by Elsevier Science Ltd.PT: J; CR: BRATT K, 1996, J ORG CHEM, V61, P2109 CHAMBERLIN AR, 1984, TETRAHEDRON, V40, P2297 EVANS DA, 1990, J AM CHEM SOC, V112, P7001 FUJIOKA H, 1993, HETEROCYCLES, V35, P665 GARAVELAS A, 1995, TETRAHEDRON LETT, V36, P463 GIESE B, 1985, TETRAHEDRON LETT, V26, P1197 MAVROPOULOS I, 1996, TETRAHEDRON LETT, V37, P3751; NR: 7; TC: 3; J9: TETRAHEDRON LETT; PG: 4; GA: WT464Source type: Electronic(1
Congressman Ed Perlmutter's letter to the Colorado Wood Utilization and Marketing Program, dated February 15, 2008
No full textRead by Mike Eckhoff at Can forests meet our energy needs? The future of forest biomass in Colorado conference, February 21, 2008, Colorado State University, Fort Collins, Colorado
- …
