12,469 research outputs found
Differing effects of familiarity/kinship in the social transmission of fear associations and food preferences
No full textDatasets and analysis for "Differing effects of familiarity/kinship in the social transmission of fear associations and food preferences"
Patterns of Arc mRNA expression in the brain following dual recall of fear- and reward-based socially acquired information
No full textPatterns of Arc mRNA expression in the brain following dual recall of fear- and reward-based socially acquired informatio
Altering Perceived Context: Transportation Cues Influence Novelty-Induced Context Exploration
No full textAltering Perceived Context: Transportation Cues Influence Novelty-Induced Context Exploration
Note: this is updated (expanded) dataset. An earlier version was uploaded to this repository on Mar2, 2021
Effect of Demonstrator Reliability and Recency of Last Demonstration on Acquisition of a Socially Transmitted Food Preference
No full textData set for "Effect of Demonstrator Reliability and Recency of Last Demonstration on Acquisition of a Socially Transmitted Food Preference
CO2 reactivity but not orexin activity differentially predicts alcohol-seeking behavior after extinction and retrieval-extinction in rats
No full textData and analysis code for manuscript submitted to ACER
Appetitive Behavior in the Social Transmission of Food Preference Paradigm Predicts Activation of Orexin-A producing Neurons in a Sex-Dependent Manner
No full textOrexin-producing cells in the lateral hypothalamic area have been shown to be involved in a wide variety of behavioral and cognitive functions, including the recall of appetitive associations and a variety of social behaviors. Here, we investigated the role of orexin in the acquisition and recall of socially transmitted food preferences in the rat. Rats were euthanized following either acquisition, short-term recall, or long-term recall of a socially transmitted food preference and their brains processed for orexin-A and c-Fos expression. We found that while there were no significant differences in c-Fos expression between control and experimental subjects at any of the tested timepoints, females displayed significantly more activity in both orexinergic and non-orexinergic cells in the lateral hypothalamus. In the infralimbic cortex, we found that social behavior was significantly predictive of c-Fos expression, with social behaviors related to olfactory exploration appearing to be particularly influential. We additionally found that appetitive behavior was significantly predictive of orexin-A activity in a sex-dependent matter, with the total amount eaten correlating negatively with orexin-A/c-Fos colocalization in male rats but not female rats. These findings suggest a potential sex-specific role for the orexin system in balancing the stimulation of feeding behavior with the sleep/wake cycle
CO2 reactivity is associated with individual differences in appetitive extinction memory
No full textData and analysis code for manuscript in submissio
Carbon dioxide reactivity predicts fear expression after extinction and retrieval-extinction in rats
No full textCues present during a traumatic event may result in maladaptive fear responses. These responses can be attenuated through extinction learning, which is a core component of exposure therapy. Exposure/extinction is effective for some, but not all. We recently demonstrated that carbon dioxide (CO2) reactivity predicts fear extinction memory and orexin activation, and that orexin activation predicts fear extinction memory, suggesting that a CO2 challenge may enable identifying whether an individual is a good candidate for an extinction-based approach. Another method to attenuate conditioned responses, retrieval-extinction, modifies the original associative memory via distinct neural mechanisms. The purpose of the present study was to examine whether we could replicate previous findings that retrieval-extinction is more effective than extinction at preventing the return of fear and that CO2 reactivity predicts fear memory after extinction. We also examined whether CO2 reactivity predicts fear memory after retrieval-extinction
Conspecific interactions predict social transmission of fear in female rats
No full textDataset and analysis codes for "Conspecific interactions predict social transmission of fear in female rats", submitted to Scientific Reports
Observing a trained demonstrator influences associative appetitive learning in rats
No full textThe ability to acquire information about the environment through social observation or instruction is an essential form of learning in humans and other animals. Here, we assessed the ability of rats to acquire an association between a light stimulus and the presentation of a reward that is either hidden (sucrose solution) or visible (food pellet) via observation of a trained demonstrator. Subsequent training of observers on the light-reward association indicated that while observation alone was not sufficient for observers to acquire the association, contact with the reward location was higher in observers that had had a demonstrator when the light cue predicted a sucrose reward. Additionally, we found that in the visible reward condition, levels of demonstrator orienting and food cup contact during the observation period tended to be positively correlated with the corresponding behavior of their observer. This relationship was only seen during later sessions of observer training. Together, these results suggest that while our models were not sufficient to induce associative learning through observation alone, demonstrator behavior during observation did influence how their paired observer’s behavioral response to the cue evolved over the course of direct individual training
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