117,500 research outputs found

    Neurofibroma plessiforme non NF-1 associato

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    Il neurofibroma plessifonnc è un tumore che origina dalle guaine delle fibre nervose periferiche ed è frequentemente associato alla neurofibromatosi di tipo l (malattia di von Recklinghausen). In letteratura sono descritti rari casi di neurofibroma p lessi forme isolato non associato a tale sindrome genetica.Plexiform neurofibroma is an uncommon tu m or of the pcripheral n erve sheaths. l t is frequently associatcd with neurofibromatosis type-1 ( von Reck linghausen 's diseasc ). l n l iteraturc iso lated pie x i form neurofibroma has been rarely reported

    Terpenes of Salvia species leaf oils: chemosystematic implications."

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    Wild specimens of Salvia L. were collected in three different moments of anthesis and their volatile leaf oils were analyzed by GC/GCMS. The quantitative terpene composition is very variable with the anthesis. S. bertolonii is the richest species in a-thujone. S. officinalis is characterized by high percentages of 1,8 cineole, 4-terpineol, isorboneol and a -bisabolol. In S. verticillata high percentages of borneol and {3-cariophyllene are present. In the three species a-thujone was always more abundant than ß-thujone. The three taxa are characterized by peculiar combinations of terpenoids. The multivariate analysis of the chemical data indicates the degree of affinity between the three taxa and their chemotaxonomical status. Some components of Salvia essential oil have pharmaceutical activities

    Linfocitoma cutis da Borrelia: localizzazione atipica in un adulto

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    ll linfocitoma cutis è una rara manifestazione cutanea della malattia di Lyme riscontrabile in Europa nel 3% dei pazienti affetti da borreliosi. In genere si manifesta con una singola lesione eritemato-bluastra nodulare o in placca di varie dimensioni che tende a ingrandirsi lentamente. lllin focitoma cutis è raro negli adulti e la localizzazione più frequente è in prossimità dell 'areola mammaria. Nel caso descritto la peculiarità è legata alla sede della lesione, la regione lombare.8orrelial lymphocytoma is a rare skin manifestation of Lyme disease. lt is usually a single bluish-red nodule or plaque, that slowly enlarges, varying in size from millimeters to few centimeters. 8 orrelial lymphocytoma is rare in adult patients and it is localized in the breast. In our report interestingly borrelial lymphocytoma is localized in lumbar region

    Bilateral auricular classic Kaposi's sarcoma

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    In 2009, a 57-year-old man was referred to our maxillo facial surgery department for the appearance of a reddish-purplish swelling on his right helix. The lesion was more than 1 cm in length and did not show changes for 3 months. He was otherwise healthy, without any predisposing factors. The patient denied smoking, alcohol misuse and intravenous drug use. He had no family history of similar lesions or Kaposi's sarcoma. The lesion was completely excised and the surgical defect reconstructed with a localflap. In 2011 the same patient returned to our attention because of the appearance of a new lesion, similar to the first one on the other auricle. The lesion was completely removed. The same situation recurred in September 2012, when the patient presented a new little reddish-purplish swelling of 3 mm on the left helix. The lesion was excised. The patient has not reported further lesion at present

    Procedures and operating instructions for diagnosis in vascular anomalies and pathology

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    In the last 30 years a revolution has occurred in the diagnosis and management of vascular anomalies. The great changes began with Mulliken and Glowacki separation of hemangiomas and vascular anomalies. Their work has now morphed into the ISSVA classification. Subsequently the discovery of the significance of the presence of GLUT-1 in the diagnosis of the hemangiomas of infancy gave us a new marker in our quest for accurate classification. Now genetic breakthroughs have led us into a “Star Wars” like environment in the experimental laboratory. During all these events the critical role of the pathologist has become more evident. Understanding the histopathology of anomalies has greatly aided in our approach to therapies. Moreover, genetic findings do not have full significance without the morphologic framework
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