61 research outputs found
Mitochondrial Polymorphisms, in The D-Loop Area, Are Associated with Brain Tumors
No full textObjective
This study was carried out to evaluate the relationship between mtDNA D-loop variations and the pathogenesis of a brain tumor.
Materials and Methods
In this experimental study, 25 specimens of brain tumor tissue with their adjacent tissues from patients and 454 blood samples from different ethnic groups of the Iranian population, as the control group, were analysed by the polymerase chain reaction (PCR)-sequencing method.
Results
Thirty-six variations of the D-loop area were observed in brain tumor tissues as well as the adjacent normal tissues. A significant difference of A750G (P=0.046), T15936C (P=0.013), C15884G (P=0.013), C16069T (P=0.049), T16126C (P=0.006), C16186T (P=0.022), T16189C (P=0.041), C16193T (P=0.045), C16223T (P=0.001), T16224C (P=0.013), C16234T (P=0.013), G16274A (P=0.009), T16311C (P=0.038), C16327T (P=0.045), C16355T (P=0.003), T16362C (P=0.006), G16384A (P=0.042), G16392A (P=0.013), G16394A (P=0.013), and G16477A (P=0.013) variants was found between the patients and the controls.
Conclusion
The results indicated individuals with C16069T [odds ratio (OR): 2.048], T16126C (OR: 2.226), C16186T (OR: 3.586), G16274A (OR: 4.831), C16355T (OR: 7.322), and T16362C (OR: 6.682) variants with an OR more than one are probably associated with a brain tumor. However, given the multifactorial nature of cancer, more investigation needs to be done to confirm this association
Tail Risk Transmission: A Study of the Iran Food Industry
No full textThis paper extends the extreme downside correlation (EDC) and extreme downside hedge (EDH) methodology to model the interdependence in the sensitivity of assets to the downside risk of other financial assets under severe firm-level and market conditions. The model is applied to analyze both systematic and systemic exposures in the Iranian Food Industry. The empirical application investigates (1) which company is the safest for investors to diversify their investment, and (2) which companies are the “transmitters” and “receivers” of downside risk. We study the return series of 11 companies and the Food Industry index publicly listed on the Tehran Stock Exchange. The data covers daily close prices from 2015–2020. The result shows that Mahram Manufacturing is the safest to hedge equity risk, and Glucosan and Behshahr Industries are the riskiest, while Gorji Biscuit is central to risk transmission, and Pegah Fars Diary is the main “receiver” of risk in turbulent times
Motamed-al-Dowleh Gorji and Fars State
No full textAbstract The Shiraz and Mamasani Conquest by Manoochehr Khan Motamed-al-Dowleh Gorji and his dominance over this land and the whole Fars State, from 1834 to1836 AD is one of the most important historical events in Fars and Iran during the Qajar dynasty. In his manuscript, ‘Madayih Al-Motamedieh’, written in his name to describe his political life, intentionally or unintentionally, the events that happened during these two years are briefly and practically distorted. Unfortunately, in other first-hand sources, only brief and repetitive references to this period have been made. This paper aims at explaining Shiraz and Mamasani Conquest by Manoochehr Khan Motamed-al-Dowleh and his political style in Fars based on first-hand sources. Moreover, this article also discusses the importance of why the state of Fars has been so important in the eyes of the Qajar government and has always been the center of discord and policy-making. Introduction This paper is based on the memoir ‘Madayih Al-Motamedieh’, applying a personal historiographical method to describe the biography of a Qajar politic called Manoochehr Khan Motamed-al-Dowleh Gorji, written in 1843 AD. As the title shows, this memoir praises him; however, it is worth mentioning that Mirza Mohammad Ali Bahar, through his talent and subtlety in writing, has portrayed his personality and behavior. The main question in this paper is why a memoir, written to portray Motamed-al-Dowleh’s conquests, has only briefly mentioned Shiraz and Mamasani conquest even though this is one of his most important achievements. Surprisingly, other sources have ignored what has happened during these two years too. It seems that the conquest had been so disastrous that a memoir, which aimed at praising a governor, had to hide the facts. Other sources, however, need to be searched considering why they had refrained from mentioning these events. The author is Mirza Mohammad Ali Mazhab Isfahani, called Farhang/Bahar. In a long ‘introduction’, he explains the dominance of Motamed-al-Dowleh Gorji. Manoochehr Khan Gorji had a noble family in Georgia, Russia. He was captured in 1803 during the Iran-Russia wars and was taken to Tehran. It seems that he was castrated by the government and was sent as a slave to the king’s palace. This painful misfortune left a lifelong psychological effect on him. He used his culture and knowledge of some languages and political talent to find an important place in the palace. After Mirza Abdolvahab Nishat Isfahani died in 1829, Manoochehr Khan replaced him. During Fath-Ali Shah and Mohammad Shah, two Qajar kings, he became the governor of Fars. Materials & Methods This research is a library and contrastive analysis of first-hand sources to explain the subject of research according to the memoir ‘Madayih Al-Motamedieh.’ Different sources have mentioned the events very briefly. The authors of this study used the contrastive method to collect different parts like a puzzle from different sources to put forward a holistic picture of what had happened during those two years. Discussion of Results & Conclusions Motamed Al-Dowleh had authority over the affairs. According to many sources, he helped Mohammad Shah to strengthen his power over Tehran, Isfahan, and Fars. Later, Mohammad Mirza joined Motamed Al-Dowleh, the governor of Guilan to fight against other claimants. Georgians supported Mohammad Shah in all affairs. Motamed Al-Dowleh was sent to conquer Fars state in 1834. He then passed the doors of Fars and conquered the State in that year after three days. After a while, he attacked country people to get their property. It seems that most of these issues are not mentioned in the memoir, issues like the suicide of women in Fars. As it is observed in general histories, local sources, and other reports, the government of Manoochehr Khan on Fars state and nearby states had been a government of terror and horror. The tower that he made out of living human bodies of Fars was so horrendous, which is reflected in the itineraries of travelers. The reason behind this inhuman atrocity maybe for his ruthless personality. Even based on psychological studies, it is possible to find a type of suppressed anguish and anger resulted from his castration. Furthermore, Fars state was a wealthy state because of farming and trading, therefore the central government advised governors to use force to get high taxes from states’ heads, tradesmen. Then the central government played the role of a savior by dismissing the governor and confiscating the properties. This happened about Manoochehr Khan too. It is not strange why a memoir written about Motamed Al-Dowleh has ignored his inhumane atrocities. Based on documents, his two-year government on Fars was a government of deception. The researchers have to collect the parts of the puzzle form different texts to conclude what had happened to urban and rural societies during the Qajar was a dark, ruthless image
Static permittivity of environmentally relevant low-concentration aqueous solutions of NaCl, NaNO3, and Na2SO4
No full textIn this paper, the result of a systematic study and molecular mechanisms governing the dielectric spectra of aqueous solutions of NaCl, NaNO3, and Na2SO4 with environmentally relevant concentrations (∼mmol/l) are presented, for frequencies from 200 MHz up to 20 GHz and at temperature 25.00 ± 0.01 °C. The measured spectra were fitted with a Debye relaxation model using a non-linear, weighted, least-squares analysis. Conductivity was measured independently to reduce uncertainty in obtaining other parameters by spectral fitting. Careful experimentation provided dielectric data of sufficiently low uncertainty to enable observation of polarization mechanisms that emerge only in the low-concentration regime. The data were fitted by a concentration-dependent parametric model that includes terms accounting for internal depolarizing fields and the solvent dilution effect (mixture relation), the kinetic depolarization effect, the dielectric saturation effect, and the Debye–Falkenhagen effect that accounts for the contribution of ionic atmosphere polarization. It has been shown that, in NaCl and NaNO3 solutions at sufficiently low concentrations, the static permittivity increases due to the Debye–Falkenhagen effect. It has also been shown that, to calculate the number of irrotationally bound water molecules ZIB, the measured static permittivity values should be corrected to account for the contributions of kinetic depolarization and Debye–Falkenhagen effects. Otherwise, unrealistic values of ZIB are obtained. An explanation for the different strengths of the Debye–Falkenhagen effect observed for the different electrolyte solutions, essentially due to the electrophoretic effect and coordination number, is also presented.This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Gorji, Amin, and Nicola Bowler. "Static permittivity of environmentally relevant low-concentration aqueous solutions of NaCl, NaNO3, and Na2SO4." The Journal of Chemical Physics 153, no. 1 (2020): 014503 and may be found at DOI: 10.1063/1.5144301. Posted with permission.</p
Comparison of Embolic Load in Femoropopliteal Interventions: Percutaneous Transluminal Angioplasty Versus Stenting
No full textPurpose: To compare the incidence of distal emboli occurring during percutaneous transluminal angioplasty (PTA) and primary stent on the superficial femoral artery (SFA) Methods: A total of 50 consecutive patients were entered in a prospective, randomized trial. Inclusion criteria were the presence of symptomatic limb ischemia due to stenosis or occlusion of the SFA. An embolic protection device was placed in the popliteal artery. The patients were then randomly assigned to undergo primary stent implantation or PTA. The filters were retrieved and sent for histologic examination. Results: Stenting in the SFA produced more emboli (1.44 mm3) than PTA (0.772 mm3), P =.031. Reanalyzing the patients according to actual treatment performed, volume of debris in the stent group was 1.271 mm3 and in the PTA group was 0.191 mm3, P =.00087. Conclusion: Volume of embolized material during endovascular interventions in the SFA-above-knee popliteal artery is higher when a stent is used. © The Author(s) 2012
Late time cosmic acceleration from natural infrared cutoff
No full textAbstractIn this paper, inspired by the ultraviolet deformation of the Friedmann–Lemaître–Robertson–Walker geometry in loop quantum cosmology, we formulate an infrared-modified cosmological model. We obtain the associated deformed Friedmann and Raychaudhuri equations and we show that the late time cosmic acceleration can be addressed by the infrared corrections. As a particular example, we applied the setup to the case of matter dominated universe. This model has the same number of parameters as ΛCDM, but a dynamical dark energy generates in the matter dominated era at the late time. According to our model, as the universe expands, the energy density of the cold dark matter dilutes and when the Hubble parameter approaches to its minimum, the infrared effects dominate such that the effective equation of state parameter smoothly changes from weff=0 to weff=−2. Interestingly and nontrivially, the unstable de Sitter phase with weff=−1 is corresponding to Ωm=Ωd=0.5 and the universe crosses the phantom divide from the quintessence phase with weff>−1 and Ωm>Ωd to the phantom phase with weff<−1 and Ωm<Ωd which shows that the model is observationally viable. The results show that the universe finally ends up in a big rip singularity for a finite time proportional to the inverse of the minimum of the Hubble parameter. Moreover, we consider the dynamical stability of the model and we show that the universe starts from the matter dominated era at the past attractor with weff=0 and ends up in a future attractor at the big rip with weff=−2
Synthesis, characterization and antibacterial activities of Mo(VI) and Cu(II) complexes derived from tridentate ONO Schiff base ligands
No full textDioxomolybdenum(VI) and copper(II) complexes were synthesized using H2L1 and H2L2 tridentate Schiff base ligands. The ligands were derived from the condensation 2-hydroxy-4-methoxysalicylaldehyde or 2-hydroxy-4-methoxyacetophenone with 2-aminopropanol, respectively. Both complexes were characterized by physico-chemical and spectroscopic methods. Dimeric nature of the Mo(VI) complexes was revealed by IR spectroscopy. Furthermore, MoO2L2(VI) nanoparticles were synthesized by Ultrasonic irradiation.. Elemental analysis, scanning electron microscopy, and FT-IR spectroscopy were used to characterize the nanoparticles. The Schiff base ligands and their complexes have been studied for antibacterial activity against Gram positive and Gram negative bacteria. The results indicated that the Mo(VI) and Cu(II) complexes were effective against all of studied bacteria and its effectiveness was higher for, Escherichia coli
Activation energy and binary chemical reaction on unsteady MHD Williamson nanofluid containing motile gyrotactic micro‐organisms
No full textThe author presents the influence of Arrhenius activation energy and binary chemical reaction on an unsteady magnetohydrodynamics Williamson nanofluid with motile gyrotactic micro-organisms. The governing equations are converted to coupled ordinary differential equations with similarity transformations and the fifth-order Runge-Kutta Fehlberg method and the shooting algorithm is applied to solve these equations using the appropriate boundary conditions. A detailed investigation considering the effects of different physical parameters on the profiles like velocity, temperature, concentration, and density of motile gyrotactic micro-organisms was done and plotted graphically. It is found that the thermal boundary layer enhances for the chemical reaction rate and the solutal boundary layer increases for activation energy. Furthermore, the nondimensional Williamson parameter reduces for the velocity profile. The author studied the wall temperature gradient of different fluids and found that temperature gradient decreased for the present study. Comparisons of the present result with published work were done to verify the present code
Grey-body factors and Hawking radiation of black holes in 4D Einstein-Gauss-Bonnet gravity
No full textThe (3+1)-dimensional Einstein-Gauss-Bonnet theory of gravity which breaks the Lorentz invariance in a theoretically consistent and observationally viable way has been recently suggested by Aoki, Gorji and Mukohyama [5]. Here we calculate grey-body factor for Dirac, electromagnetic and gravitational fields and estimate the intensity of Hawking radiation and lifetime for asymptotically flat black holes in this theory. Positive coupling constant leads to much smaller evaporation rate and longer life-time of a black hole, while the negative one enhances Hawking radiation. The grey-body factors for electromagnetic and Dirac fields are smaller for larger values of the coupling constant. © 2020 The Author(s
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