247 research outputs found
Efecto de la administración profiláctica del ciprofloxacino en la incidencia de infecciones graves y evolución de las citocinas pro- y anti-inflamatorias en pacientes cirróticos: estudio aleatorizado doblemente a ciegas /
\ua0tesis que para obtener el grado de Doctorado en Ciencias Medicas, presenta Felix Ignacio Tellez Avila ; tutores principales de tesis José Sifuentes Osornio, Florencia Vargas Vorácková, Moises Selman Lama167 páginas :\ua0ilustracionesDoctorado en Ciencias Medicas\ua0Universidad Nacional Autónoma de México,\ua02012\ua0Programa de Posgrado en Ciencias Médicas, Odontológicas y de la Salu
Posible participación de los fibrocitos en la expansión tisular de fibroblastos en fibrosis pulmonar idiopática /\ua0tesis que para obtener el grado de Doctor en Ciencias Biomédicas, presenta Carolina García de Alba Rivas ; asesor Moises Selman L., Annie Pardo Semo, Alfonso Dueñas González
. 96 páginas :\ua0ilustraciones. Doctorado en Ciencias Biomédicas\ua0UNAM, Facultad de Medicina,\ua0201
Fathers' perspectives: a qualitative approach to understanding the experiences of fathers of children in special education
There has been a growing interest in understanding and increasing father involvement in their child's education. Ongoing research has documented the positive effects of father involvement; however, fathers continue to feel disconnected from their child's school and educational program. Not surprisingly, research has indicated that fathers of children in special education are also underutilized by school practitioners. Rather than reaching out to both parents, school personnel continue to disregard fathers and rely predominately on the child's mother. Because federal policy mandates parent collaboration on special education teams, there is a need for special education personnel to begin reaching out to fathers in order to increase their involvement in the process. In this study, in-depth qualitative interviews were conducted with fathers of children in special education to better understand their involvement in the process. This study examines their experiences engaging with school personnel and their perspectives on their roles in their child's special education program. Their emotional reactions to the process are examined within the in-depth data providing a rich description of their experiences. Findings indicate that the fathers in this study are strong advocates for their children and are very concerned for their children's education. In addition, the fathers want to be included more often and to be seen as equal partners in their child's special education program. Furthermore, these fathers offered recommendations for special education personnel to better facilitate the involvement of fathers. Suggestions for school psychology practice and topics for future research are discussed.Psy.DIncludes bibliographical references (p. 69-73)by Jeffrey S. SelmanIncludes abstrac
Efecto del factor de crecimiento para fibroblastos acidos (FGF-1), sobre la expresion y sintesis de colagena, metaloproteinasas e inhibidores tisulares de metaloproteinasas (TIMPs), en fibroblastos de pulmon humano normal
Via aerea periferica y zona de transicion en fibrosis pulmonar idiopatica y alveolitis alergica extrinseca
How effective are national remedies in securing international justice?
Karakul, Selman (Dogus Author)This chapter examines the role of NGOs in assuring corporate accountability by exposing human rights infringements within under-developed legal systems. Non-governmental organizations (NGOs) are instrumental in bringing public awareness to the existence of abuse. NGOs have a role to set the agenda for government and to identify key human rights issues. Through research, conducted on behalf of intergovernmental organizations (IGOs), governmental bodies or delegations, NGOs help enforce laws as the research conducted enables the state to focus on enforcement. The remedial gap in Third World states regarding corporate-related human rights abuse has not deterred NGOs from seeking justice. South Africa is used as a case study to highlight the role of NGOs in the country and their relevance to the African continent. The US Alien Tort Statute (ATS) is a piece of legislation that has transformed into a powerful tool in which perpetrators of human rights violation are held accountable under tort law
Human lung myofibroblast-derived inducers of alveolar epithelial apoptosis identified as angiotensin peptides
Earlier work from this laboratory found that fibroblasts isolated from fibrotic human lung [human interstitial pulmonary fibrosis (HIPF)] secrete a soluble inducer(s) of apoptosis in alveolar epithelial cells (AECs) in vitro [B. D. Uhal, I. Joshi, A. True, S. Mundle, A. Raza, A. Pardo, and M. Selman. Am. J. Physiol. 269 ( Lung Cell. Mol. Physiol. 13): L819–L828, 1995]. The cultured human fibroblast strains most active in producing the apoptotic activity contained high numbers of stellate cells expressing α-smooth muscle actin, a myofibroblast marker. The apoptotic activity eluted from gel-filtration columns only in fractions corresponding to proteins. Western blotting of the protein fraction identified immunoreactive angiotensinogen (ANGEN), and two-step RT-PCR revealed expression of ANGEN by HIPF fibroblasts but not by normal human lung fibroblasts. Specific ELISA detected angiotensin II (ANG II) at concentrations sixfold higher in HIPF-conditioned medium than in normal fibroblast-conditioned medium. Pretreatment of the concentrated medium with purified renin plus purified angiotensin-converting enzyme (ACE) further increased the ELISA-detectable ANG II eightfold. Apoptosis of AECs in response to HIPF-conditioned medium was completely abrogated by the ANG II receptor antagonist saralasin (50 μg/ml) or anti-ANG II antibodies. These results identify the protein inducers of AEC apoptosis produced by HIPF fibroblasts as ANGEN and its derivative ANG II. They also suggest a mechanism for AEC death adjacent to HIPF myofibroblasts [B. D. Uhal,, I. Joshi, C. Ramos, A. Pardo, and M. Selman. Am. J. Physiol. 275 ( Lung Cell. Mol. Physiol. 19): L1192–L1199, 1998].</jats:p
Produccion autocrina de factor de crecimiento derivado de plaquetas por fibroblastos derivados pulmon normal y con fibrosis idiopatica
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