154 research outputs found
Patient treatment pathways of multidrug-resistant tuberculosis cases in coastal South India: Road to a drug resistant tuberculosis center
No full textDr Priya Rathi1, Dr Kalpita Shringapure2, Dr B Unnikrishnan1, Abhinav Pandey3, Abhirami Nair3 1. Kasturba Medical College, Department of Community Medicine, Manipal Academy of Higher Education, Mangalore, India, 575001 2. Medical College Baroda, Department Preventive and Social Medicine, Gujarat, India 3. Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India 575001 Corresponding Author Dr Priya Rathi Department of Community Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India 57500
Comparison of the bronchodilatation produced by inhalation of ipratropium bromide and salbutamol sequentially and in fixed dose combination in stable bronchial asthma patients
No full textObjectives : The combination of a 43-2 agonist and an anticholinergic agent is of-ten used to manage bronchial asthma. However, it is unclear whether these drugs should be given separately in sequence or in a fixed dose combination for maximum effect. Methods : 27 patients with stable bronchial asthma were given the above two drugs in two separate sessions one week apart. In one session they were given the above two drugs as a fixed dose combination and in the other session, they were given se-quentially with salbutamol following ipratropium after 30 minutes. Spirometry was performed at baseline and 15, 30 and 60 minutes after inhaling the second drug. Results : Both groups showed significant improvement in forced vital capacity (FVC), forced expiratory time in one second (FEV 1 ), peak expiratory flow rate (PEFR) and forced expiratory flow (FEF 25-75 ) from baseline upto one hour. FVC increased initially and then stabilized; however, the increase was more sustained in the group getting combination treatment. This group also showed a higher rise in FEV 1 (p=0.02). Both FEV 1 and FEF 25-75 decreased after 30 minutes in the group that received sequential therapy. PEFR increased continuously till 60 minutes in both groups and there was no significant difference between them (p=0.98). Interpretation and Conclusion: Both methods of drug dosing produce equivalent bronchodilation. Fixed dose combinations produced a more sustained rise in FVC and higher increase in FEV 1 . Hence fixed dose combinations are more effective short-term bronchodilators and give an added advantage of reducing the number of inhalers required, thus improv-ing compliance
Correlation of Global Longitudinal Strain with Functional Status of Patients with Left Ventricular Systolic Dysfunction
No full textBackground: Two-dimensional (2D) left ventricular ejection fraction (LVEF) is a well-known parameter to assess the functional status of the patients. Recently, global longitudinal strain (GLS) has emerged as a more sensitive tool for assessing left ventricular (LV) systolic function. We aimed to assess the superiority of GLS by 2D speckle-tracking echocardiography over 2D LVEF in patients with moderate-to-severe LV systolic dysfunction (LVSD) calculated using Simpson's biplane method of disks, in predicting the functional status of the patients. Materials and Methods: One hundred patients in age group 18–80 years with moderate-to-severe LVSD (2D LVEF <40%) were included. New York Heart Association class 4 patients and patients of rheumatic heart disease or valvular heart disease were excluded. 2D LVEF was calculated using Simpson's method. 2D GLS was assessed using automated function imaging technique. The Minnesota Living with Heart Failure Questionnaire (MLHFQ) was used to assess functional status of patients with moderate-to-severe LVSD. Results: Results showed that 2D GLS better correlated with functional status of the patients (P ≤ 0.0001) than 2D LVEF (P = 0.619). Patients who had better 2D GLS had better functional status according to MLHFQ. Conclusion: Correlation of functional status of patients with poor LVSD was superior with 2D GLS when compared to 2D LVEF. Since strain imaging is an inexpensive tool, it can be easily applied to assess functional status in large number of patients without adding any additional cost
A novel robust low voltage and fault ride through for wind turbine application operating in weak grids
No full textPrecision mechanism design for 3-DOF in-plane alignment in µm and sub-mrad level
No full textTo assist in the fast alignment of tiny components, Prodrive Technologies has developed a type of camera system called the Component Alignment Sensor (CAS) that is used on a pick-and-place machine. The system uses an optical target as the reference during its assembly and final testing steps. Two main components of the target are a glass reticle and a stainless steel carrier that are bonded together. These two components need to be precisely aligned w.r.t. each other. Till now, the alignment between the reticle and carrier has been performed manually by relative movement between them created by hand. However, this method has some limitations, including, but not limited to, an increase in the alignment time and sensitivity to external jerks or disturbances. Accordingly, the thesis objective is to create a (detailed) design of an alignment mechanism to perform the 3-DOF in-plane alignment in µm and sub-mrad level. The research starts with the formulation of design requirements, followed by concept design, evaluation and selection, and finally a detailed design of the mechanism. A flexure-based alignment mechanism was proposed and designed that uses fine screws for actuation. Various design principles were applied to construct a stiff and compact mechanism that uses a limited number of adjustment steps for the alignment. The process was supported by calculations and analyses that contributed to decision making. Besides, the assembly and alignment procedures of the alignment mechanism were described. The thesis is concluded with a plan to verify if the matured design meets the set requirements.Mechanical Engineering | Optomechatronic
Modeling of a neural network based controller for vibration suppression of a building structure
No full textDynamic mechanical analysis of waste tyre rubber filled brake friction composite materials
No full textDevelopment of Vegetable Based Low Fat Snack
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Role of selected Food Ingredients in Speciality Foods: Spices and Herbs
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
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