205 research outputs found
Vision Loss Associated with Hyaluronic Acid Fillers: A Systematic Review of Literature
No full textBackground: With the global increase in the use of injectable fillers, more cases with serious adverse events such as skin ischemia and vision loss are being reported. This article aims to review the role of HA fillers, as a subgroup separate from fat graft and non-HA fillers, in causing vision loss and to elucidate various features and outcomes of post-HA filler vision loss. Methods: The preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines were used to report this review. A total of 29 articles presenting 60 unique cases of post-HA filler vision loss were identified in the literature. Based on various inclusion and exclusion criteria, 26 articles with details of 44 cases were included in this study. Results: The majority of cases were seen in women and in the 20–40 years age group. The maximum number of cases was reported from Korea, followed by China. Nearly half of the cases reported after HA filler-related visual complications had partial loss of sight, hence ‘partial vision loss’ and ‘complete vision loss’ were used as differentiating descriptive terms to the degree of ‘blindness.’ Nearly all the cases were unilateral, with immediate onset of visual signs and symptoms. The nose, glabella, and forehead were the most commonly implicated areas, while no cases of post-HA filler vision loss were reported from lower face anatomical areas, including the chin, jawline, and lips. Partial vision loss after HA filler has a better prognosis than complete vision loss. HA filler volumes as low as 0.2 ml can cause permanent, complete vision loss, which is suggestive of the embolic nature of HA filler blockage. Ophthalmic artery occlusion (OAO) and central retinal artery occlusion (CRAO) were the two most commonly involved arterial obstruction patterns followed by branch retinal artery occlusion (BRAO). BRAO is the most favorable involved arterial pattern for a chance of recovery after HA filler-related vision loss while CRAO and OAO patterns carry a very poor prognosis. Conclusion: Post-HA filler vision loss is nearly always of immediate onset. Partial vision loss after HA filler injection with the involvement of smaller branches of the retina, other than central retinal artery or ophthalmic artery, has more favorable visual outcomes. Level of Evidence III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266
Egocentric Analysis of Dash-Cam Videos for Vehicle Forensics
No full textVideo acquisition using dashboard-mounted cameras has recently achieved massive popularity around the world. One of the major developments following the dash-cam's popularity is that videos captured by them can be used as testimony during scenarios, like traffic violations and accidents. The widespread deployment of dash-cams brings new problems ranging from the compromise of privacy by uploading these videos on public websites using videos captured from other cars for making fraudulent claims. Therefore, there is a compelling need to address the problems associated with the usage of dash-cam videos. In this paper, we discuss and highlight the importance of the emerging area of multimedia vehicle forensics. We propose an algorithm for linking a dash-cam video to a specific car. The proposed algorithm is useful for various applications, for example, insurance companies can authenticate the origin of video before processing the claim. In a different scenario of illegitimate video upload on the Web, the video can be traced back to the car it originated from. To this end, we make use of motion blur extracted from dash-cam videos for generating a discriminative feature. We observe that the subtle motion pattern of every vehicle can serve as its unique signature. We extract motion blur from dash-cam videos and use random forest trees for classifying the vehicle correctly. The experimental results on thousands of frames obtained from dash-cam videos of several cars show the effectiveness of our approach. We further investigate the process of forging the signature of a car and propose a counter forensics method to detect such forgery. Also, we discuss the application of our technique to other potential platforms where the camera can be mounted, for example, on the chest of a person. We believe that ours is the first work that describes this new area of research
Generating actionable suggestions for improving user engagement with online advertisements
No full textAn online advertising system receives an advertisement from an advertiser. The system analyzes the advertisement, extracts its features and provides to the advertiser a quality rating for the advertisement which depends on a user engagement factor such as the predicted dwell time for the ad, given its features. The system further provides to the advertiser suggestions for improvements to the advertisement, such as a list of actionable guidelines that can improve the expected dwell time of the ad, and likely its conversion rate
Content name resolution service implementation for cache and forward network architecture
No full textCache aNd Forward (CNF) is a proposed architecture for content delivery services in the future Internet. The CNF architecture takes advantage of reductions in storage to design a network that directly addresses the mobile content delivery problem. The CNF architecture uses a content name resolution service protocol, along with a reliable hop-by-hop transport protocol, storage aware routing protocol in place of end-to-end TCP for reliable delivery of large files. This thesis presents the algorithms proposed for a distributed name resolution protocol and design and experimental evaluation of the protocol on ORBIT in context of a multi-hop wireless access network scenario. The protocol is designed using hashing technique such that when a host queries for a file, the name service will be triggered and will return the addresses of nodes that cache the file. Since our architecture is about caching and forwarding large content files, enabling hosts to retrieve files from the network and not necessarily from the origin server, we need to uniquely identify the files. To that effect, we propose to identify a file using a unique content identifier (CID) where CID is obtained by a one way hashing (SHA1) on the content itself. The aim here is to optimize selection of cache location and serve the host with the file from the nearest location. If the selected cache location is determined to be temporarily degraded, either due to poor channel conditions or mobility, the protocol uses multiple hash technique to provide alternate cache locations and the decision is based on the ETT metric provided by the routing protocol. The CNRS protocol over multi-hop 802.11 access networks with CNF routers has been implemented as a real-time proof-of-concept prototype on the ORBIT testbed. Baseline results for CNRS with hop-by-hop transport show that content based CNF network architecture performs better than TCP/IP stack. Using different content distributions, we have shown that multiple hashing, popularity based and location based caching provide significant gains over the baseline algorithm.M.S.Includes bibliographical referencesby Puneet Katari
The effects of perhexiline on the rat coronary vasculature
No full textThe predominant site and mechanism(s) of perhexiline-induced coronary vasodilatation were investigated in the rat heart. Perhexiline was more potent in the Langendorff perfused heart than in the left anterior descending coronary artery (EC50; 0.27 microM, confidence limits 0.19-0.39: 2.7 microM, 2.0-3.4, respectively). Selective endothelial inactivation with Triton X-100 in the perfused heart, reduced the response to perhexiline 1 microM (76+8% to 30+3% of control). 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) 3 microM, Nomega-nitro-L-arginine 100 microM, or a combination of the latter with indomethacin 10 microM, had no significant effect on responses to perhexiline in the perfused heart. Unlike bradykinin-induced vasodilatation, responses to perhexiline were not inhibited by tetrabutylammonium 1 mM, or charybdotoxin 20 nM. SKF525A 5 microM inhibited both perhexiline and bradykinin responses, while apamin 1 microM and glibenclamide 3 microM inhibited neither. Perhexiline exerts partially endothelium-dependent coronary vasodilator effects in the rat, predominantly on small coronary arteries, which appear to be independent of nitric oxide (NO), prostacyclin and the endothelium-derived hyperpolarising factor (EDHF) released by bradykinin.Jennifer A. Kennedy, Puneet Mohan, Maria A. Pelle, Steven R. Wade, John D. Horowit
Determination of the octanol-water partition coefficient of indolicidin and indolicidin45 using micellar electrokinetic chromatography
No full textUnsteady MHD nanofluid flow past a stretching sheet with Stefan blowing effect: HAM solution
No full text
Influence of g–jitter on the Rayleigh-Bénard convection in nanofluids with internal heat source
No full textA comparison of titers of anti-Brucella antibodies of naturally infected and healthy vaccinated cattle by standard tube agglutination test, microtiter plate agglutination test, indirect hemagglutination assay, and indirect enzyme-linked immunosorbent assay
No full textAim: We determined the antibody response in cattle naturally infected with brucellosis and normal healthy adult cattle vaccinated during calf hood with strain 19.
Materials and Methods: The antibody titers were measured by standard tube agglutination test (STAT), microtiter plate agglutination test (MAT), indirect hemagglutination assay (IHA), and indirect enzyme-linked immunosorbent assay (iELISA) as per standard protocols.
Results: The mean STAT titers were 1.963±0.345 in infected cattle and 1.200±0.155 in healthy vaccinated cattle. The difference was extremely significant (p<0.0001). The mean MAT titers were 2.244±0.727 in infected cattle and 1.200±0.155 in healthy vaccinated cattle. The difference was very significant (p<0.005). The mean IHA titers in infected cattle were 2.284±0.574, and those in healthy vaccinated cattle were 1.200±0.155. The difference was extremely significant (p=0.0002). However, the difference in mean iELISA titers of infected cattle (1.3678±0.014) and healthy vaccinated cattle (1.367±0.014) was non-significant. The infected animals showed very high titers of agglutinating antibodies compared to the vaccinated animals. However, it cannot be ascertained whether these antibodies are due to vaccine or response to infection. Since the infected animals had been vaccinated earlier, the current infection may suggest that vaccination was unable to induce protective levels of antibody. The heightened antibody response after infection may also indicate a secondary immune response to the antigens common to the vaccine strain and wild Brucella organisms.
Conclusion: The brucellosis infected animals showed very high titers of agglutinating antibodies compared to the vaccinated animals
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