2 research outputs found
THE INCIDENCE OF PERFORATED APPENDICITIS AMONG PEDIATRIC PATIENTS IN KHARTOUM NORTH TEACHING HOSPITAL, SUDAN
No full textIntroduction: Acute appendicitis is a common emergency condition in paediatrics with different ages. The perforated appendicitis is one of the most serious complications of acute appendicitis which may lead to peritonitis. The aim of our study is to calculate the incidence of perforated appendicitis. Methods: This is a retrospective cross-sectional study has been conducted at Khartoum north teaching hospital. The total number of patients was 214. Results: the most common age in this study are 13 years old and the mean age is 11 years, 128 of cases were male 59.8% and 86 were females 40.2%. All cases of our study presented with fever 100%, 80.8% presented with right iliac fossa pain, and anorexia 100%. 50.5% of cases came within the first day of presentation and 26.6% of cases came in 4thday of presentation, all cases presented with right iliac fossa tenderness, 15.9% of cases presented with perforated acute appendicitis, 67.29% of cases operated after 6 hours, 5.61% operated in more than 6 hours and 27.1% operated after 6 weeks. Conclusion: In this study the incidence of perforated acute appendicitis was 15.9% which is low in comparison with another study because there was no delay in appendectomy operation and the majority of patients came within the first day of the disease
THE ROLE OF HYDROXYCHLOROQUINE AS MONOTHERAPY IN MANAGING EARLY UNDIFFERENTIATED ARTHRITIS: A PROSPECTIVE HOSPITAL-BASED STUDY
No full textIntroduction: Early undifferentiated arthritis (EUA) is a common form of arthritis comprising, joint pain, stiffness and swelling with no definitive diagnosis. Patients of EUA can progress to other forms of rheumatic arthropathies such as rheumatoid arthritis or remain in the same form or spontaneously disappear. The main focus of this study is to explore the potential effect of hydroxychloroquine (HCQ) in management of EUA as a monotherapy treatment. Methods: This is a prospective hospital-based study which was conducted in Almwada hospital in Khartoum, Sudan. The study included thirty patients of EUA. Full clinical examination and history were done by a rheumatologist, and all the related investigations were obtained, and they all received HCQ after EUA diagnosis has been established. Result: The study shows that 96% of the patients responded well to the treatment and 10% had their duration of treatment doubled to show a favorable response. We also found that female patients weremore commonly affected than male ones with higher incidence among middle aged as compared to others. After treatment with HCQ, 86.6% of the patients showed average mean decrease in erythrocyte sedimentation rate (ESR) by 44%, the other 13.4%, even though they were symptoms free after treatment they showed increased level of ESR by 30% average. Conclusion: In the present study we found out most of the EUA patients are well responded to the HCQ treatment, and most of them respond from the first course of treatment, the study also shows higher incidence among female in compared to male
