11 research outputs found

    Processability Theory Revisited: A Critical Approach

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    Article reference: Mozayan, M. (2015). Processability theory revisited: A critical approach. ELT Voices, 5 (5), 25-30. Abstract: In order to revisit Processability, the theory which links psychology and linguistics in a very direct way to demonstrate what we know about languages, this paper primarily glances over the Achilles' heel of the error analysis in delineating the developmental patterns in the language learners. It also refers to the second way in which samples of learner language are collected over a period of time so as to identify when specific linguistic features emerge; this is what the Processability theory (PT) does. By addressing the concepts such as property and transition theories as well as the developmental and logical problems of the learners, the paper then magnifies the central hypothesis of the theory holding that at any stage of development, learners can produce and comprehend only those L2 linguistic forms which their current state of mind can handle. Later, the criticisms leveled at the theory are put forth. And finally concluding remarks wrap up the issue

    Can Preoperative Serum Level of Creatinine Predict New-Onset Atrial Fibrillation in Non-Diabetic Male Patients Undergoing Open Heart Surgery? A Retrograde View

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    Renal dysfunction is a risk marker in patients who candidate for coronary artery bypass graft (CABG). Renal disorder is associated with prolonged stays in intensive care unit and hospital, morbidity and mortality. Aim of this study is specific evaluation of association between preoperative creatinine (Cr) with atrial fibrillation (AF) after elective off-pump CABG in non-diabetic male patients with normal ejection fraction. Two hundred non-diabetic male patients with normal ejection fraction undergoing elective off pump CABG surgery enrolled in this cross-sectional study and were stratified by present or absence of postoperative atrial fibrillation: patients with postoperative new-onset atrial fibrillation (n=100) as group 1 and patients without new-onset postoperative atrial fibrillation as group 2 (n=100). Preoperative serological test of the participants, such as serum creatinine, were recorded in their medical dossiers. Data were analyzed in SPSS-16 software and tested for association between atrial fibrillation with creatinine level by using student t test, chi-square test or logistic regression. Cr level in patients with and without AF three days before surgery were 1.8±0.3 and 1.0±0.4 respectively (P value for Cr=0.00). On surgical day, mean Cr level in patients with and without AF were 1.6±0.2 and 1.1±0.5 respectively (P value for Cr = 0.00). Of the 100, male patients with postoperative AF, duration and frequency of recurrence of AF were not associated with Cr at three days before surgery and on surgical days (P>0.05). Patients with postoperative AF had unsuitable status of renal function compare to patients without AF; however, preoperative serum creatinine cannot associate with duration and frequency of recurrence of AF

    Relationship of admission mean platelet volume, platelet distribution width and white blood cells with ST resolution in patients with acute ST segment elevation myocardial infarction treated with streptokinase without history of previous cardiovascular surgery

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    Background: Mean platelet volume (MPV) and platelet distribution width (PDW), markers of platelet reactivity, and white blood cell count (WBC-C), a marker of inflammation, have been shown to be predictive of unfavorable outcomes among survivors of ST elevation myocardial infarction (STEMI).we aimed to evaluate the value of admission of MPV, PDW and WBC-C for the prediction of ST segment resolution, in patient with acute STEMI treated with Streptokinase. Materials and Methods: This cross sectional study conducted on 280 patients with STEMI treated with streptokinase, from August 2009 until August 2011, in Afshar cardiovascular center, Yazd, Iran. Blood samples were obtained on admission in 280 patients with STEMI. According to sum of ST segment resolution and Schroder′s method, patients divided two groups ((patients with ST resolution≥ 70% versus group with ST resolution < 70%)).The best cut off value of MPV, PDW and WBC-C for prediction of ST resolution (STR) were identified by using the receiver operating characteristic curve. The optimum cut off level was determined by selecting points of test value that provided the greatest sum of sensitivity and specificity. Results: Of 280 patients enrolled this study, 39.3% of the patients with STR≥70% and in 60.7% with STR<70% were found. Patients in the STR < 70% group had higher admission MPV (10.6 ± 0.8 vs. .9.5 ± 0.8, P = 0.00) and higher PDW (13.8 ± 1.8 vs. 11.8 ± 1.7, P = 0.00)and higher WBC-C (12.1 ± 3.1 vs. 10.5 ± 2.5, P = 0.00) compare with patients with ST resolution ≥ 70%.The best cut off value of MPV for predicting STR < 70%was 10/05 fl (sensitivity 71/8 and specificity 80.9%) and for PDW was 12.85 fl (sensitivity 71.2% and specificity 83.6%) and for WBC-C was 12.65 × 1000 (sensitivity 42.9% and specificity 82.7%). The greatest area under the receiver operating characteristic (ROC) curve and greatest predicting value for ST resolution lower 70% was due to PDW (area = o.812, P = 0/00). Conclusion: MPV, PDW and WBC-C at admission might be valuable in the prediction of impaired STR and in planning the need for adjunctive therapy to improve outcomes with STEMI treated with Streptokinase .We can speculate that acute STEMI patients having MPV-PDW and WBC-C values above their′s cut off patients should be considered for stronger antiplatelet and helps anti inflammation treatment to be able to attain a favorable ST resolution and better clinical outcome

    Intra‑operative grading of coronary artery atherosclerosis associated with homocysteine levels in postmenopausal women undergoing elective off‑pump CABG surgery

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    Background: Atherosclerosis is one of the common causes of morbidity and mortality, in postmenopausal women. Homocysteine, a sulfur‑containing amino acid product of methionine metabolism, may play an important role in the development of cardiovascular diseases. This study was designed to evaluate the relationship between intra‑operative grading of coronary artery atherosclerosis and homocysteine level in postmenopausal women who were candidates for off‑pump coronary bypass graft surgery (CABG). Materials and Methods: In this cross‑sectional study, 136 postmenopausal women (with the mean age of 54.9±4 years) were enrolled as candidates for elective off‑pump CABG. For each patient the extent and severity of atherosclerosis was assessed by intra‑operative grading (IOG) and Gensini score system. Total homocysteine was determined with ELISA method after 12 hours of fasting. The patients were classified into two groups (diffuse vs. discrete) based on intra‑operative findings. Finally the relation between age, IOG, and Gensini score with homocysteine level was assessed by ANOVA, T‑test, and Tukey HSD test. Results: There was a positive correlation between intra‑operative grading and homocysteine level in both groups (P=0.005). The association between Gensini score and homocysteine was significant in higher levels of hyperhomocysteinemia (P &lt; 0.05). The homocysteine level also increased with age; therefore, patients were classified into two categories (&lt;54 years and ≥54 years) by Levene test. Statistical analysis indicated no relationship between IOG, Gensini score, and homocysteine level in the patients who were younger than 54 years (P=0.3, P=0.2), but significant relation was detected between IOG, Gensini score, and homocysteine in the patients who were older than 54 years with diffuse or discrete lesions in coronary arteries (P=0.001, P=0.001). Conclusion: According to our findings, homocysteine level increases in post‑menopausal women that can be an important risk factor for atherosclerosis and cardiovascular diseases.Keywords: Coronary artery atherosclerosis, homocysteine, intra‑operative grading, menopause, off‑pump coronary bypass surgeryNigerian Medical Journal | Vol. 53 | Issue 4 | October-December | 201
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