213 research outputs found
The Emergency Conceptual Framework Big Picture
No full textThe Emergency System Conceptual Framework Big Picture gives an insight to better manage and plan for different emergencies (Accidents, Incidents, Crisis, Disasters, Catastrophes).Under License of the Author, Mr.Bijan Yavar. The Copyright Holder is the Author as mentioned. © Bijan Yavar, 2002
Postsurgical inflammation as a causative mechanism of venous thromboembolism
No full textSurgery is associated with an increased risk of venous thromboembolic events (VTE) including deep vein thrombosis and pulmonary embolism. Although the current treatment regiments such as mechanical manipulation and administration of pharmacological prophylaxis significantly reduced the incidence of postsurgical VTE, they remain a major cause of postoperative morbidity and mortality worldwide. The pathophysiology of venous thrombosis traditionally emphasizes the series of factors that constitute Virchow triad of factors. However, inflammation can also be a part of this by giving rise to a hypercoagulable state and endothelial damage. The inflammatory response after surgery, which is initiated by a cytokine "storm" and occurs within hours of surgery, creates a prothrombotic environment that is further accentuated by several cellular processes including neutrophil extracellular traps formation, platelet activation, and the generation of tissue factor-bearing microparticles. Although such inflammatory markers are elevated in undergoing surgery, the precise mechanism by which they give rise to venous thrombosis is poorly understood. Here, we discuss the potential mechanisms linking inflammation to thrombosis, and highlight strategies that may minimize surgical inflammation and reduce the incidence of postoperative VTE
Important Concepts on Emergency Management
No full textImportant Concepts on Emergency Management in this version tends to explain about the Ambiguity, Risk, Uncertainty and Certainty context of Risk Planning, Design and Management and also the structure of Response in the Headquarters (Off-Scene) and also the field (On-Scene)
Concepts, Definitions, Annotation
In English and Persian LanguagesUnder License of the Author, Mr.Bijan Yavar. The Copyright Holder is the Author as mentioned.
© Bijan Yavar, 202
Medical management of risk factors for vascular disease
No full textPeripheral arterial disease (PAD) is a powerful marker of the risk of cardiovascular events such as stroke and myocardial infarction, even in asymptomatic patients. The development of PAD is underpinned by both modifiable risk factors, including smoking, diabetes, dyslipidaemia, hypertension and obesity and non-modifiable risk factors, including male gender and increased age. Optimizing medical management of risk factors, with tight control of diabetes, antiplatelet therapy and exercise, can significantly reduce risk of cardiovascular morbidity and mortality
Commentary:Understanding the Role of EndoAnchors in Infrarenal Endovascular Aneurysm Repair
No full textLymphoedema
No full textAbstract Lymphoedema is caused by the failure of lymphatic drainage leading to an accumulation of protein-rich fluid in the interstitium. It can be classified as primary (genetic cause) or secondary. Early diagnosis is essential to prevent progression. In the Western world, lymphoedema is most commonly secondary to cancer and its treatment. In endemic regions, filariasis is an important cause and a global eradication programme is underway. Recently, progress has been made in understanding the embryology of the lymphatic system and specific genetic causes of primary lymphoedema, leading to the hope that medical therapies may improve lymphatic function. Surgery is currently reserved for advanced disease and is performed in specialist centres, primarily to reduce the bulk of swollen tissue
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