3,183 research outputs found
PostMod: sequence based prediction of kinase-specific phosphorylation sites with indirect relationship
No full textBackground: Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understanding protein function and revealing cellular signal transductions. Especially, phosphorylation is a ubiquitous process with a large portion of proteins undergoing this modification. Experimental methods to identify phosphorylation sites are labor-intensive and of high-cost. With the exponentially growing protein sequence data, development of computational approaches to predict phosphorylation sites is highly desirable. Results: Here, we present a simple and effective method to recognize phosphorylation sites by combining sequence patterns and evolutionary information and by applying a novel noise-reducing algorithm. We suggested that considering long-range region surrounding a phosphorylation site is important for recognizing phosphorylation peptides. Also, from compared results to AutoMotif in 36 different kinase families, new method outperforms AutoMotif. The mean accuracy, precision, and recall of our method are 0.93, 0.67, and 0.40, respectively, whereas those of AutoMotif with a polynomial kernel are 0.91, 0.47, and 0.17, respectively. Also our method shows better or comparable performance in four main kinase groups, CDK, CK2, PKA, and PKC compared to six existing predictors. Conclusion: Our method is remarkable in that it is powerful and intuitive approach without need of a sophisticated training algorithm. Moreover, our method is generally applicable to other types of PTMs.
Letter from Y. Yoshida to Mrs. K. Nakatani, January 1. 1982
No full textLetter from Yoshiko Yoshida to Kikuye Nakatani. It encloses a picture of a memorial monument dedicated to the soldiers of the Japanese battleship, Yamato, including the ship anchor. Yoshiko writes about the calligraphy on the rock in the photo, which was drawn by her husband, Mitsuru Yoshida.The collection consists of documents, diaries, letters, books, calendars, newspapers, photographs, artifacts and audiovisual media pertaining to Kikuyo Morimoto Nakatani, a Japanese-born woman who lived in Isleton, California. During World War II, her family was incarcerated in the Minidoka and Tule Lake incarceration camps. After the war, she moved to Los Angeles and studied tea with Madame Sosei Matsumoto, and became a tea master acknowledged by the Urasenke Headquarters in Japan. The collection also contains letters from her son, Kunio, who served aboard the Yamato battleship for the Empire of Japan during World War II
レーザー発振効率改善に向けたNd/Cr:YAGセラミックにおけるエネルギー移乗過程の解明
No full text主査：中野人志 教授 学内授与番号：工第232号
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Noriaki Miyanaga, Kana Fujioka, Masahiro Nakatsuka, Minoru Yoshida “Temperature dependence of optical properties in Nd/Cr:YAG materials” Journal of Luminescence 2014, Volume 148, Pages 342-346
https://doi.org/10.1016/j.jlumin.2013.12.044 掲載
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Kana Fujioka, Masahiro Nakatsuka, Minoru Yoshida, Toshihiro Yamada, Junji Kawanaka, Noriaki Miyanaga “Temperature dependent fluorescence decay and energy transfer in Nd/Cr:YAG ceramics” Optical Materials 2019, Volume 90, Pages 215-219
https://doi.org/10.1016/j.optmat.2019.02.032 掲載
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Kana Fujioka, Toshihiro Yamada, Minoru Yoshida “Concentration-dependent fluorescence decay and energy transfer in Cr3+ and Nd3+ co-doped Y3Al5O12 ceramic powder” Japanese Journal of Applied Physics 2021, 60, 032001
https://doi.org/10.35848/1347-4065/abdd04 掲載
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Kana Fujioka, Toshihiro Yamada, Minoru Yoshida "Temperature dependence of the small-signal gain of a Cr3+ and Nd3+ co-doped Y3Al5O12 ceramic" Japanese Journal of Applied Physics 2021, 60, 072003
https://doi.org/10.35848/1347-4065/ac06b3 掲載
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Kana Fujioka, Toshihiro Yamada, Minoru Yoshida “Analyses of energy transfer of Cr 3+ and Nd 3+ co doped Y 3 Al 5 O 12 ceramic powders at the 4 T 1 level of Cr 3+ ion excitation” Japanese Journal of Applied Physics 2022, 61, 022004
https://doi.org/10.35848/1347-4065/ac468e 掲
Elucidation of energy transfer process in Nd/Cr:YAG ceramic for improving laser oscillation efficiency
No full text近畿大学Kindai University博士（工学）主査：中野人志 教授 学内授与番号：工第232号
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Noriaki Miyanaga, Kana Fujioka, Masahiro Nakatsuka, Minoru Yoshida “Temperature dependence of optical properties in Nd/Cr:YAG materials” Journal of Luminescence 2014, Volume 148, Pages 342-346
https://doi.org/10.1016/j.jlumin.2013.12.044 掲載
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Kana Fujioka, Masahiro Nakatsuka, Minoru Yoshida, Toshihiro Yamada, Junji Kawanaka, Noriaki Miyanaga “Temperature dependent fluorescence decay and energy transfer in Nd/Cr:YAG ceramics” Optical Materials 2019, Volume 90, Pages 215-219
https://doi.org/10.1016/j.optmat.2019.02.032 掲載
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Kana Fujioka, Toshihiro Yamada, Minoru Yoshida “Concentration-dependent fluorescence decay and energy transfer in Cr3+ and Nd3+ co-doped Y3Al5O12 ceramic powder” Japanese Journal of Applied Physics 2021, 60, 032001
https://doi.org/10.35848/1347-4065/abdd04 掲載
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Kana Fujioka, Toshihiro Yamada, Minoru Yoshida "Temperature dependence of the small-signal gain of a Cr3+ and Nd3+ co-doped Y3Al5O12 ceramic" Japanese Journal of Applied Physics 2021, 60, 072003
https://doi.org/10.35848/1347-4065/ac06b3 掲載
Yoshiyuki Honda, Shinji Motokoshi, Takahisa Jitsuno, Kana Fujioka, Toshihiro Yamada, Minoru Yoshida “Analyses of energy transfer of Cr 3+ and Nd 3+ co doped Y 3 Al 5 O 12 ceramic powders at the 4 T 1 level of Cr 3+ ion excitation” Japanese Journal of Applied Physics 2022, 61, 022004
https://doi.org/10.35848/1347-4065/ac468e 掲載doctoral thesi
Federated Community Church program, May 24, 1942
No full textProgram for worship services at the Federated Community Church in Elk Grove, California. Verso includes a handwritten note by Ed Yoshida which reads, "This is to certify that the following personal property belongs to Ed H. Yoshida to be used or stored at the discretion of Ed H. Yoshida for the duration of the present emergency or until such time as the owner desires to terminate this trust. Dated May 25, 1942." Includes an inventory of personal belongings.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications
Constituencies and Interests: An Afterword
No full textThis is the author accepted manuscript. The final version is available from Yoshida Shoten Publishing via the DOI in this record.Book is in Japanese. This version of the chapter is in EnglishThe essays in this volume each probe an aspect of the relationship between parliamentary constituencies and interest groups in the workings of the parliament at Westminster between the mid-sixteenth and mid-nineteenth centuries, during which period it went from being the representative assembly of England and Wales, to include Scotland after 1707 and Ireland after 1801, rendering it a truly ‘British’ parliament. [...
Homogenization with respect to Gibbs measures for periodic drift diffusions on lattices
No full textBernabei S, Röckner M, Yoshida MIW, Albeverio S. Homogenization with respect to Gibbs measures for periodic drift diffusions on lattices. Comptes Rendus Mathematique. 2005;341(11):675-678
DESIGN FORMULAS OF COMPOSITE COLUMNS AND BEAM-COLUMNS PART I
No full textThe strength of short composite columns are described and design methods for them arereviewed. Then researches on the strength of long composite columns and design formulasare reviewed. Finally new design formulas for long columns and beam-columns applyingsuperposition method are proposed. It is shown that the errors involved are reasonably small, in addition to the simplicity and the advantage that two independent design formulas forsteel part and reinforced concrete part can be used.The strength of short composite columns are described and design methods for them arereviewed. Then researches on the strength of long composite columns and design formulasare reviewed. Finally new design formulas for long columns and beam-columns applyingsuperposition method are proposed. It is shown that the errors involved are reasonably small,in addition to the simplicity and the advantage that two independent design formulas forsteel part and reinforced concrete part can be used
Komponieren für die Arbeiterschaft: Huldreich Georg Früh als Festspielkomponist
No full textIn seinen Lebenserinnerungen beschreibt Kurt Früh die Zusammenarbeit mit seinem Bruder Huldreich Georg mit Wärme und aufrichtiger Bewunderung: 1 Damit spricht der Theatermacher; Schriftsteller und Regisseur Früh eine Epoche der Volksbühne Zürich an - die 193Oer-Jahre -, die als ihr Höhepunkt bezeichnet werden kann.2 Nach einer Orientierungsphase, die wenig politisch bestimmt war und in der auch schwankhafte Stücke aufs Programm gesetzt wurden, entwickelte sich die Bühne ab 1932 zu einem Spielort des proletarischen Theaters mit Verbindung zum Schaffen Bertolt Brechts und mit starken Banden zur Sozialdemokratie. lmmer stärker wurde aber auch der Einfluss der Kommunistischen Partei der Schweiz, an deren Veranstaltungen die Volksbühne beteiligt war.+ ID: 589925 + Serientitel: Schriften der Eugen und Yoshida Früh-Stiftun
In the Heart of a Dynamic Chromatin
No full textAn audacious bet on transforming histone H4 into a real-time sensor probe has been won by the group of Minoru Yoshida, who designed the first FRET probes capable of signaling the occurrence of dynamic site-specific acetylations in live cells
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