163 research outputs found
L'innovazione come leva strategica per attrarre e trattenere gli investitori
No full textLo studio mostra come l'innovazione abbia conseguenze che vanno al di là del prezzo delle azioni e dipendono dalla natura degli investitori. Lo studio evidenza l'importanza dell'eterogeneità degli investitori - in termini di attivismo e rilevanza dell'investimento - nella risposta all'innovazione
Far leva sulla creatività dei consumatori per alimentare con continuità il processo innovativo: evidenze empiriche dal settore moda
No full textAttraverso uno studio sperimentale nel contesto della moda, gli autori mostrano come il processo creativo in presenza di vincoli generi dei risultati più innovativi del tradizionale processo senza vincoli
Consumatore aumentato. L’innovazione del consumatore per superare la crisi
No full textDopo aver richiamato alcune evidenze che qualificano la crisi pandemica come una crisi della domanda e del consumatore, il contributo analizza alcuni modelli elaborati dalla letteratura sul consumatore quale soggetto centrale nella produzione di valore, evidenziando le determinanti della sua produttività e, di conseguenza, le aree sulle quali ogni genere di innovazione tecnologica in grado di potenziarne la produzione di valore dovrebbe essere oggetto di sperimentazione e adattamento.
Su queste basi viene quindi tratteggiata una mappa delle aree di innovazione del consumatore. Aree di recupero della produttività ma anche di potenziamento del valore sulle quali sperimentare e, di conseguenza, adeguare nuove soluzioni tecnologiche che abilitino l’incorporazione, fisica o cognitiva, dell’innovazione nelle routine comportamentali fino a configurare un vero e proprio consumatore aumentato. Un consumatore, insomma, che producendo innovazione non solo guida la ripresa economica ma disegna con sempre maggiore discrezionalità il campo del gioco concorrenziale
Correction to: Diffusion, outcomes and implementation of minimally invasive liver surgery: a snapshot from the I Go MILS (Italian Group of Minimally Invasive Liver Surgery) Registry
No full textA technical error led to incorrect rendering of the author group in this article. The correct authorship is as follows: Luca Aldrighetti, Francesca Ratti, Umberto Cillo, Alessandro Ferrero, Giuseppe Maria Ettorre, Alfredo Guglielmi, Felice Giuliante, Fulvio Calise on behalf of the Italian Group of Minimally Invasive Liver Surgery (I GO MILS) The collaborators are: Raffaele Dalla Valle, AOU Parma, Parma; Vincenzo Mazzaferro, Istituto Nazionale Tumori, Milano; Elio Jovine, Ospedale Maggiore, Bologna; Luciano Gregorio De Carlis, Ospedale Niguarda Ca’ Granda, Milano; Ugo Boggi, AOU Pisana, Pisa; Salvatore Gruttadauria, ISMETT, Palermo; Fabrizio Di Benedetto, AOU Policlinico di Modena, Modena; Paolo Reggiani, Ospedale Maggiore Policlinico, Milano; Stefano Berti, Ospedale Civile S.Andrea, La Spezia; Graziano Ceccarelli, Ospedale San Donato, Arezzo; Leonardo Vincenti, AOU Consorziale Policlinico, Bari; Giulio Belli, Ospedale SM Loreto Nuovo, Napoli; Guido Torzilli, Istituto Clinico Humanitas, Rozzano; Fausto Zamboni, Ospedale Brotzu, Cagliari; Andrea Coratti, AOU Careggi, Firenze; Pietro Mezzatesta, Casa di Cura La Maddalena, Palermo; Roberto Santambrogio, AO San Paolo, Milano; Giuseppe Navarra, AOU Policlinico G. Martino, Messina; Antonio Giuliani, AO R.N. Cardarelli, Napoli; Antonio Daniele Pinna, Policlinico Sant’Orsola Malpighi, Bologna; Amilcare Parisi, AO Santa Maria di Terni, Terni; Michele Colledan, AO Papa Giovanni XXIII, Bergamo; Abdallah Slim, AO Desio e Vimercate, Vimercate; Adelmo Antonucci, Policlinico di Monza, Monza; Gian Luca Grazi, Istituto Nazionale Tumori Regina Elena, Roma; Antonio Frena, Ospedale Centrale, Bolzano; Giovanni Sgroi, AO Treviglio-Caravaggio, Treviglio; Alberto Brolese, Ospedale S.Chiara, Trento; Luca Morelli, AOU Pisana, Pisa; Antonio Floridi, AO Ospedale Maggiore, Crema; Alberto Patriti, Ospedale San Matteo degli Infermi, Spoleto; Luigi Veneroni, Ospedale Infermi AUSL Romagna, Rimini; Giorgio Ercolani, Ospedale Morgagni Pierantoni, Forlì; Luigi Boni, AOU Fondazione Macchi, Varese; Pietro Maida, Ospedale Villa Betania, Napoli; Guido Griseri, Ospedale San Paolo, Savona; Andrea Percivale, Ospedale Santa Corona, Pietraligure; Marco Filauro, AO Galliera, Genova; Silvio Guerriero, Ospedale San Martino, Belluno; Giuseppe Tisone, Policlinico Tor Vergata, Roma; Raffaele Romito, AOU Maggiore della Carità, Novara; Umberto Tedeschi, AOU Integrata Verona, Verona; Giuseppe Zimmitti, Fondazione Poliambulanza, Brescia
Na-D-glucose cotransport by intestinal brush border membrane vesicles of Antarctic fish.
No full textThe relational side of Intellectual capital. An empirical study on brand evaluation and financial performance
No full textPurpose – This study aims to validate a direct method to measure relational capital through the estimation of corporate brands. Considering the influence of relational capital management in leading performance and brand development, we consider brand value as a proxy for relational capital. The main research goal is to extend the previous literature on Intellectual capital, Financial performance and Brand management by elaborating and testing an original approach for valuating corporate brands using regression analysis on multiples based on firm-specific accounting data and market information.
Design/methodology/approach – We propose two econometric models, for both listed and non-listed companies, which consider brand valuations made by primary consulting entities (Interbrand, Brand Finance, BrandZ, European Brand Institute) and multiples derived from accounting and market data of firms. Models were tested on a sample of non-financial firms for the period from 2006 to 2019, distinguishing between IAS/IFRS-based and US GAAP-based reporting standards.
Findings – The empirical results show that the identified set of market and accounting multiples proved to be significant information for estimating the value of brands within the IAS/IFRS framework, while a lower explanatory power was assessed for US GAAP firms. Furthermore, the empirical evidence confirm that the direct, relative approach based on multiples is more accurate for valuating listed firms than non-listed firms. Robustness analysis demonstrate that findings do not change significantly when the reference datasets and the main assumptions of the models are altered.
Research limitations/implications – The statistical significance of the analysis is limited by the non-objective nature of brand value estimates. The use of additional sources for brand valuations might allow for the further assessment of the robustness of the relationships identified.
Practical implications – Due to their efficacy and ease of use, the proposed models represent valid practical tools for managers, investors, analysts and professional evaluators.
Originality/value – This work contributes to the existing literature through the identification of significant, stable relationships between brand values and the main economic, financial and asset characteristics of firms; the identification of those relationships would allow for the extension of the multiples approach also to the evaluation of brands
The relational side of Intellectual capital: an empirical study on Brand evaluation and financial performance
No full textPurpose – This study aims to validate a direct method to measure relational capital through the estimation of corporate brands. Considering the influence of relational capital management in leading performance and brand development, we consider brand value as a proxy for relational capital. The main research goal is to extend the previous literature on Intellectual capital, Financial performance and Brand management by elaborating and testing an original approach for valuating corporate brands using regression analysis on multiples based on firm-specific accounting data and market information.
Design/methodology/approach – We propose two econometric models, for both listed and non-listed companies, which consider brand valuations made by primary consulting entities (Interbrand, Brand Finance, BrandZ, European Brand Institute) and multiples derived from accounting and market data of firms. Models were tested on a sample of non-financial firms for the period from 2006 to 2019, distinguishing between IAS/IFRS-based and US GAAP-based reporting standards.
Findings – The empirical results show that the identified set of market and accounting multiples proved to be significant information for estimating the value of brands within the IAS/IFRS framework, while a lower explanatory power was assessed for US GAAP firms. Furthermore, the empirical evidence confirm that the direct, relative approach based on multiples is more accurate for valuating listed firms than non-listed firms. Robustness analysis demonstrate that findings do not change significantly when the reference datasets and the main assumptions of the models are altered.
Research limitations/implications – The statistical significance of the analysis is limited by the non-objective nature of brand value estimates. The use of additional sources for brand valuations might allow for the further assessment of the robustness of the relationships identified.
Practical implications – Due to their efficacy and ease of use, the proposed models represent valid practical tools for managers, investors, analysts and professional evaluators.
Originality/value – This work contributes to the existing literature through the identification of significant, stable relationships between brand values and the main economic, financial and asset characteristics of firms; the identification of those relationships would allow for the extension of the multiples approach also to the evaluation of brands
Na(+)-D-glucose cotransport by intestinal BBMVs of the Antarctic fish Trematomus bernacchii.
No full textIntestinal nutrient absorption in fish adapted to low temperature was investigated by isolating, with a Mg2+-precipitation procedure, brush-border membrane vesicles (BBMVs) from intestines of the Antarctic teleost Trematomus bernacchii. In particular, D-glucose transport was analyzed by measuring both 1) fluorescence changes of the electrical potential-sensitive dye 3,3'-diethylthiadicarbocyanine iodide. [DiS-C-2(5)] and 2) intravesicular uptake of D-[C-14]glucose. Results demonstrated that transport of D-glucose across intestinal BBMs of the Antarctic fish is stimulated by the presence of a transmembrane Na+ gradient (out > in) and was specifically inhibited by phloridzin. Furthermore, Na+-dependent D-glucose uptake was strongly enhanced by the presence of an electrical potential (inside-negative) across the membrane. There was a marked difference in temperature dependence of Na+-sugar cotransport between the Antarctic fish and temperate fish, such as the European yellow eel. Na+-dependent D-glucose uptake in T. bernacchii intestinal BBMV reached its maximal rate at -2-0 degrees C (close to fish living temperature) and was exponentially inactivated by incubation at higher temperatures. Kinetic analysis of D-glucose influx indicated the presence of a single Na+-dependent carrier process (apparent maximal carrier-mediated influx = 0.233 +/- 0.009 nmol . mg protein(-1). min(-1); apparent half-saturation constant for carrier-mediated influx - 0.157 +/- 0.026 mmol/l) and a nonsaturable transfer component (apparent diffusional permeability of membrane to the sugar = 0.233 +/- 0.016 mu l . mg protein(-1). min(-1)). The Na+-dependent carrier-mediated mechanism was specific for sugars, since it ws partially inhibited by the presence in the extravesicular medium of other monosaccharides, but not by ascorbic acid or amino acids of different types. These data suggest that in the intestine of Antarctic fish luminal D-glucose transport takes place by a specific Na+-dependent electrogenic secondary active transport working well at subzero temperatures
One-lung ventilation to treat hepatic dome lesion – a further step towards minimally invasive surgery: a case report
No full textAbstract Background Although liver resection is still the best treatment for primary or metastatic hepatic lesions, a conventional surgical approach may be challenging in patients with a history of previous abdominal surgery. We present a case of a 58-year-old white man with paracaval, subdiaphragmatic, recurrent hepatocellular carcinoma; he had a history of multiple abdominal surgeries. Methods In select patients, percutaneous ultrasound-guided thermal ablation is a valid non-surgical alternative due to its safety, efficacy, and good tolerability. Hepatic lesions located in the posterosuperior segments, however, can be difficult to reach via a percutaneous approach. Result For these cases, one-lung left-sided ventilation may be particularly helpful in blocking the right hemidiaphragm and improving the acoustic window to the liver. Conclusion We present a case of paracaval, subdiaphragmatic, recurrent hepatocellular carcinoma in which the tumor was only reachable after one-lung left-sided ventilation that was successfully treated by percutaneous ultrasound-guided microwave ablation
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