668 research outputs found
Age, but not anthelmintic treatment, is associated with urinary neopterin levels in semi-free ranging Barbary macaques
No full textStudying host parasite interactions and their implications for evolution and ecology recently received increasing attention, particularly with regard to host physiology and immunity. Here we assess variation of urinary neopterin (uNEO), a marker of cellular immune activation and iummunosenescence, in response to age and anthelmintic treatment in semi-free ranging Barbary macaques (Macaca sylvanus). Urinary NEO levels were measured via enzyme-immunoassay from 179 urine samples of 43 individuals between 5–29 years of age. Efficiency of treatment was assessed by Mc Master flotation on repeated faecal samples, including 18 untreated individuals as control group. We used linear mixed models with age and parasite status as main effects, controlling for sex and physical condition, assessed through urinary C-Peptide-levels, with social group and ID as random factors. Urinary NEO levels significantly increased with age, suggesting that changes in aging Barbary macaque immune responses are consistent with immunosenescence described in human and nonhuman primates and can be detected via uNEO measurements. Anthelmintic treatment, however, had no influence on uNEO levels, potentially due to quick reinfections or attenuated immune responses in repeated infections. We conclude that uNEO is a potential non-invasive marker for immune function and particularly immunosenescence in wildlife.Open-Access-Publikationsfonds 201
Never Look Back: An Alternative to Centering
No full textI propose a model for determining the hearer's attentional state which depends solely on a list of salient discourse entities (S-list). The ordering among the elements of the S-list covers also the function of the backward-looking center in the centering model. The ranking criteria for the S-list are based on the distinction between hearer-old and hearer-new discourse entities and incorporate preferences for inter- and intra-sentential anaphora. The model is the basis for an algorithm which operates incrementally, word by word. 1 Introduction I propose a model for determining the hearer's attentional state in understanding discourse. My proposal is inspired by the centering model (Grosz et al., 1983; 1995) and draws on the conclusions of Strube & Hahn's (1996) approach for the ranking of the forward-looking center list for German. Their approach has been proven as the point of departure for a new model which is valid for English as well. The use of the centering transitions in Brenn..
Detection of odor-specific response latencies in the honeybee olfactory system
No full textPamir E, Schmucker M, Strube-Bloss M, Menzel R, Nawrot MP. Detection of odor-specific response latencies in the honeybee olfactory system. In: Frontiers in Computational Neuroscience. Frontiers in Computational Neuroscience. Vol 2. Lausanne: Frontiers Media SA; 2010
Learning-induced changes at the single neuron level predict behavioral performance in the honeybee
No full textD'Albi T, Haenicke J, Strube-Bloss M, Schmucker M, Menzel R, Nawrot MP. Learning-induced changes at the single neuron level predict behavioral performance in the honeybee. Frontiers in Computational Neuroscience. 2011;5
Exposure and susceptibility drive reinfection with gastrointestinal parasites in a social primate
No full textResponsiveness of fecal immunoglobulin A to HPA‐axis activation limits its use for mucosal immunity assessment
No full text20 Pop-Stücke für Orgel
No full textSchielen Sie als Organist seit langem neidisch auf das Pop-Klavierbuch von Michael Schütz oder seine Blechbläser-Grooves? Sie können beruhigt sein, denn der Komponist hat sich nun der Orgel zugewandt und 20 Pop Stücke von "Barrelhousin" über "Keep cool" bis zu "Thats it" geschrieben, mit denen sich der Orgel fortan fantastische poppige Töne entlocken lassen werden. Sollten Sie unbedingt ausprobieren
Introduction to supercomputing at JSC
No full text"Introduction to supercomputing at JSC" course is including: Welcome (Ilya Zhukov, JSC), Anaconda is squeezing us (Robert Speck, Jakob Fritz, JSC), Introduction to JSC (Bernd Mohr, JSC), HPC in a nutshell (Ilya Zhukov, JSC), User Portal and Job Monitoring (Jolanta Zjupa, JSC), JSC Systems: JUWELS, JURECA and JUSUF (Damian Alvarez, JSC), JUST: Juelich Storage Cluster (Stephan Graf, JSC), HPC Software — Modules, Libraries & Software (Ruth Partzsch, JSC), Batch usage on JSC (Chrysovalantis Paschoulas, JSC), JupyterJSC: supercomputing in the browser (Jens Henrik Goebbert, JSC), Uniform Resource Access Compute and Cloud Resources at JSC (Björn Hagemeier, JSC), Proper pinning prevents pretty poor performance (Thorsten Hater, JSC), GPU accelerators at JSC (Andreas Herten, JSC), Deep learning on supercomputers (Alexandre Strube, JSC), Debugger And Performance Tools (Michael Knobloch, JSC), Remote Visualization (Herwig Zilken, JSC), Intel tuning for JUWELS and JURECA (Heinrich Bockhorst, Intel), JUWELS & JURECA Tuning for the platform (Patrick Küven, ParTec), LLview: best practices (Filipe Guimaraes, JSC), Parallel Debugger (Michael Knobloch, JSC
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