222 research outputs found
Supplemental_material - Sequential Organ Failure Assessment Component Score Prediction of In-hospital Mortality From Sepsis
No full textSupplemental_material for Sequential Organ Failure Assessment Component Score Prediction of In-hospital Mortality From Sepsis by Tushar Gupta, Michael A. Puskarich, Elizabeth DeVos, Adnan Javed, Carmen Smotherman, Sarah A. Sterling, Henry E. Wang, Frederick A. Moore, Alan E. Jones, and Faheem W. Guirgis in Journal of Intensive Care Medicine</p
Controversies in spine surgery, MIS versus open best evidence recommendations
No full textLumbar discectomy : Are tubular or endoscopic discectomies better than traditional microdiscectomy? / MIS: Martin H. Pham, Alexander Tuchman, John C. Liu, open: John D. Attenello, Steven R. Garfin, Richard Todd J. Allen -- Lumbar stenosis best treated with an open laminectomy? / MIS: Hasan R. Syed and Sylvain Palmer -- Facet cysts : Is there an advantage to treating synovial cysts with MIS techniques? / MIS: Jose M. Torres-Campa, Marjan Alimi, and Roger Hartl -- Transforaminal lumbar interbody fusion : MIS vs open / MIS: Rory J. Petteys, Anthony Conte, and Faheem A Sandhu, open: Jason C. Eck -- The lateral transpsoas approach versus ALIF : Do the risks of lateral interbody fusion outweigh the benefits compared to anterior lumbar interbody fusion? / MIS: Steven M. Spitz, Hasan R. Syed, and Jean-Marc Voyadzis, open: David L. Scott, and Peter G. Whang --Is AxiaLIF comparable to open Fusion with ALIF and posterolateral 360-degree fusion at L5-S1? / MIS: Venu M. Nemani and Oheneba Boachie-Adjei, open: John D. Koerner, and Todd J. Albert -- Multiple-level interbody fusion : How do two-level fusion techniques compare between open and MIS? / MIS: OluMide Ojeifo, Christopher Hills, and Robert E. Isaacs, open: P. Justin Tortolani -- Is lumbar adjacent segment degeneration best treated using MIS over open fusion techniques? / MIS: Luiz Pimenta, Luis Marchi, Leonardo Oliveira, open: Christopher M. Bono -- Degenerative scoliosis : Is there an advantage to using MIS techniques to treat degenerative scoliosis? / Chun-Po Yen, Juan S. Uribe, Christopher I. Shaffrey -- Flatback syndrome : Can lumbar flatback syndrome be treated adequately with MIS techniques? / MIS: Navid R. Arandi and Gregory M. Mundis Jr., open: Randa El Mallah and Ahmad Nassr --Can thoracic disc herniation be effectively treated using MIS techniques? / MIS: Paul W. Millhouse, Troy Mounts, Kristen E. Radcliff, open: Alexander A. Theologis, Vedat Deviren -- Posterior cervical foraminotomy / MIS: Tim Eugene Adamson, open: Andrew Hecht and Steven Joseph McAnany -- Complications of instrumentation : Is there a higher complication rate in placing instrumentation via an MIS technique compared with an open technique? / MIS: Russell G. Strom, and Anthony K. Frempong-Boadu, open: Saad B. Chaudhary and Michael J. Vives -- Dural tears : Should an MIS complication such as a dural tear routinely be opened for adequate repair or are there safe and reliable MIS techniques for dural closure? / MIS: John E. O'Toole, open: Michelle J. Clarke -- Do MIS techniques broaden the scope for geriatric spine surgery? / Michael Y. Wang -
Parents' opinions on using applied behavior analysis (ABA) to increase neurotypically developing children's level of physical activity
No full textPhysical activity is important to reduce the risk of several diseases and in some cases death. Early childhood theorists stressed the importance of physical activity, lowering its cost, and rewarding physical movements. ABA interventions were an essential part of this paper because of its importance in altering the behavior and keeping the desired change even after the intervention. In general, parents and teachers’ motivations and engagement with children were the most effective way to increase physical activity in both ABA and ECE articles. Results of this research found that general knowledge of ABA is low and there is a need to increase ABA awareness and usage in the society before directing toward specific interventions. Finally, the cost of ABA interventions without insurance coverage is astronomical, yet all children have the right to receive behavioral treatments and live in an altered environment that ensures them the best overall developmen
Author Correction: The influence of domestic manufacturing capabilities on biologic pricing in emerging economies
No full textEffect of Self-Care Guidelines on the Knowledge, Practice and Clinical Outcomes of Patients with Chronic Heart Failure Disease
No full textAbstract: Background: Self-care guidelines for patients with chronic heart failure disease (CHFD) is considered as a strategy for promoting their knowledge, practice and clinical outcomes. Aim: this study aimed to evaluate the effect of self-care guidelines on knowledge, practice and clinical outcomes of patients with CHFD through the following: 1) assessment of knowledge, practice and clinical outcomes of patients with CHFD. 2) developing and implementing self-care guidelines. 3) evaluating the effect of self-care guidelines on knowledge, practice and clinical outcomes of patients with CHFD. Study design: a quasi- experimental design was utilized to conduct this study. Setting: the study was conducted at cardiac outpatients’ clinics at Ain Shams university hospitals. Subject: a purposive sample of 60 patients with chronic heart failure disease were select. Data collection tools: 1) patients’ assessment tool 2) patient’s knowledge assessment tool regarding CHFD 3) patients’ practice observational checklists and 4) patients’ clinical outcomes assessment tool. Results: there were significant improvement in the studied patients’ knowledge, practice and clinical outcomes post guideline implementation compared to pre. Conclusion: application of self-care guidelines for patients with CHFD has positive effect on improving knowledge, practice and clinical outcomes regarding dyspnea, sleep quality, fatigue and mood. Recommendations: Further researches are recommended periodically to be carrying out on new approaches in the area of management of patients with CHFD and evaluate its effect on patients’ outcomes. Replication of the current study on a larger probability sample is recommended to achieve generalization of the results and wider utilization of the designed program. Establish interdisciplinary approach in management of CHFD.
Keywords: Self- card, clinical outcomes, chronic heart failure.
Title: Effect of Self-Care Guidelines on the Knowledge, Practice and Clinical Outcomes of Patients with Chronic Heart Failure Disease
Author: Hanan Malak Kolta Ghattas, Magda Abd El-Aziz Mohamed, Howyda Ahmed Mohamed, Jackleen Faheem Gendy
International Journal of Novel Research in Healthcare and Nursing
ISSN 2394-7330
Vol. 9, Issue 3, September 2022 - December 2022
Page No: 199-216
Novelty Journals
Website: www.noveltyjournals.com
Published Date: 14-November-2022
DOI: https://doi.org/10.5281/zenodo.7320153
Paper Download Link (Source)
https://www.noveltyjournals.com/upload/paper/Effect%20of%20Self-Care%20Guidelines-14112022-5.pdfInternational Journal of Novel Research in Healthcare and Nursing, ISSN 2394-7330, Novelty Journals, Website: www.noveltyjournals.co
Effect of different sintering temperature on fly ash based geopolymer artificial aggregate
No full textPhilip Albert Theodor Kircher. Poverty Reduction Strategies. Gottingen Studies in Development Economics. Frankfurt, Germany: Peter Lang, 2002. xiv+275 pages. Paperback. Price not given.
No full textPoverty is one of the most depressing global problems in the
world today. Therefore, there is a growing consensus among development
organisations that poverty alleviation should be the primary goal of
cooperation between the rich and the poor countries. This consensus is
due to the awareness that a widening international income gap threatens
the well-being of people in the rich countries. In this volume, the
author, Philip Kircher, offers a comprehensive study on the evolution,
the content, the different national accentuations, and the problem of
the international consensus on poverty alleviation, and provides a
systematic analysis of today’s donor strategies for development
cooperation for poverty reduction. The study focuses specifically on the
strategic positions of the World Bank, the Department for International
Development (DFID) of the United Kingdom, the Ministry for Economic
Cooperation and Development (BMZ) of Germany, and the Swedish
International Development Agency (SIDA), as well as the positions
presented by the governments of these countries in regard to
development
Design for Sustainability and Project Management Literature – A Review
No full textAbstractThe growing pressure on natural resources and increasing global trade have made sustainability issues a prime area of concern for all businesses alike. The increased focus on sustainability has impacted the way projects are conceived, planned, executed and evaluated in industries. Since project management literature has hardly been considered in design for sustainability research, this article attempts to review the points of intersection between these two fields, and explores the potential that knowledge from project management literature has in improving efficiency and effectiveness of development and implementation of design for sustainability tools
Synaptic dysfunction in human neurons with autism-associated deletions in PTCHD1-AS
No full textBackground
The Xp22.11 locus that encompasses PTCHD1, DDX53, and the long noncoding RNA PTCHD1-AS is frequently disrupted in male subjects with autism spectrum disorder (ASD), but the functional consequences of these genetic risk factors for ASD are unknown.
Methods
To evaluate the functional consequences of PTCHD1 locus deletions, we generated induced pluripotent stem cells (iPSCs) from unaffected control subjects and 3 subjects with ASD with microdeletions affecting PTCHD1-AS/PTCHD1, PTCHD1-AS/DDX53, or PTCHD1-AS alone. Function of iPSC-derived cortical neurons was assessed using molecular approaches and electrophysiology. We also compiled novel and known genetic variants of the PTCHD1 locus to explore the roles of PTCHD1 and PTCHD1-AS in genetic risk for ASD and other neurodevelopmental disorders. Finally, genome editing was used to explore the functional consequences of deleting a single conserved exon of PTCHD1-AS.
Results
iPSC-derived neurons from subjects with ASD exhibited reduced miniature excitatory postsynaptic current frequency and N-methyl-D-aspartate receptor hypofunction. We found that 35 ASD-associated deletions mapping to the PTCHD1 locus disrupted exons of PTCHD1-AS. We also found a novel ASD-associated deletion of PTCHD1-AS exon 3 and showed that exon 3 loss altered PTCHD1-AS splicing without affecting expression of the neighboring PTCHD1 coding gene. Finally, targeted disruption of PTCHD1-AS exon 3 recapitulated diminished miniature excitatory postsynaptic current frequency, supporting a role for the long noncoding RNA in the etiology of ASD.
Conclusions
Our genetic findings provide strong evidence that PTCHD1-AS deletions are risk factors for ASD, and human iPSC-derived neurons implicate these deletions in the neurophysiology of excitatory synapses and in ASD-associated synaptic impairment
- …
