571 research outputs found
Letter, Julia Gardiner Tyler to Mrs. Laura Holloway, author of First Ladies, dated September 20, 1869
No full textALS of Julia Gardiner Tyler to Mrs. Laura Holloway, author of First Ladies, dated September 20, 1869, about interviewing other first ladies. ALS.Found in:Mss. 65 T97 Additions, Series 1: Mss. Acc. 1993.19 Addition, 186
BIOPHYSICAL CONTROLS OF MARSH SOIL SHEAR STRENGTH ALONG AN ESTUARINE SALINITY GRADIENT
No full text© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Gillen, M. N., Messerschmidt, T. C., & Kirwan, M. L. Biophysical controls of marsh soil shear strength along an estuarine salinity gradient. Earth Surface Dynamics, 9(3),(2021): 413-421, https://doi.org/10.5194/esurf-9-413-2021.Sea-level rise, saltwater intrusion, and wave erosion threaten coastal marshes, but the influence of salinity on marsh erodibility remains poorly understood. We measured the shear strength of marsh soils along a salinity and biodiversity gradient in the York River estuary in Virginia to assess the direct and indirect impacts of salinity on potential marsh erodibility. We found that soil shear strength was higher in monospecific salt marshes (5–36 kPa) than in biodiverse freshwater marshes (4–8 kPa), likely driven by differences in belowground biomass. However, we also found that shear strength at the marsh edge was controlled by sediment characteristics, rather than vegetation or salinity, suggesting that inherent relationships may be obscured in more dynamic environments. Our results indicate that York River freshwater marsh soils are weaker than salt marsh soils, and suggest that salinization of these freshwater marshes may lead to simultaneous losses in biodiversity and erodibility.This research has been supported by the US National Science Foundation (grant nos. 1654374, 1426981, 1529245, and 1832221)
Atlas of canine and feline peripheral blood smears /
No full text"An illustrated guide to the morphology of blood cells, Atlas of Canine and Feline Peripheral Blood Smears covers patient assessment for common hematologic disorders and diseases in dogs and cats. Over 1,000 full-color photomicrographs depict abnormalities within each blood cell line, with multiple pictures of each morphologic abnormality and variations in their appearance. Written by pathology experts Amy Valenciano, Rick Cowell, Theresa Rizzi, and Ronald Tyler, this concise reference will enhance your skills as you interpret blood smears and recognize hematological cellular response to inflammation, infection, and toxicity."--Provided by publisher.Includes bibliographical references and index.Online resource; title from e-book title screen (ScienceDirect platform, viewed August 18, 2016)."An illustrated guide to the morphology of blood cells, Atlas of Canine and Feline Peripheral Blood Smears covers patient assessment for common hematologic disorders and diseases in dogs and cats. Over 1,000 full-color photomicrographs depict abnormalities within each blood cell line, with multiple pictures of each morphologic abnormality and variations in their appearance. Written by pathology experts Amy Valenciano, Rick Cowell, Theresa Rizzi, and Ronald Tyler, this concise reference will enhance your skills as you interpret blood smears and recognize hematological cellular response to inflammation, infection, and toxicity."--Provided by publisher.General assessment -- Red blood cells -- White blood cells -- Platelets -- Hematopoietic neoplasia -- Extracellular organisms.Produced by the publisher.Held by CAPER-BC, Langara College.Elsevie
End user development environment for decision support systems
No full textThesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2009.Cataloged from PDF version of thesis.Includes bibliographical references (p. 91-92).This thesis describes an end user programming environment that allows non-programmers to create decision support protocols for use on electronic devices. User centered design techniques were followed to identify the difficulties encountered by users when attempting to create complex protocols, specifically addressing the problems of the scale, complexity, and specificity required for a protocol to be effectively used. The result is a highly usable desktop client graphical user interface which can create protocols that can be exported in portable formats. A summative user study was conducted on the finished software in order to evaluate its success in enabling non-programmers to author protocols.by Clayton Tyler Sims.M.Eng
157 - Jordan Tyler Koehn
No full textIncludes bibliographical references.The conformations of long polymers of isoprene units such as those found in the side-chains of lipoquinones involved in bacterial (i.e. Mycobacterium tuberculosis) and eukaryotic electron transport systems (ETS) have not been characterized. First, menaquinone-2 and ubiquinone-2 were synthesized then using 1H-1H 2D NOESY and ROESY NMR spectroscopy, we demonstrated that both molecules adopt a folded, U-shaped conformation in solution and within a model membrane interface. These folded conformations are in stark contrast to the extended conformations seen in literature. Folded conformations likely affect reactivity, function, and recognition within the ETS and provide insight into drug development of potent inhibitors.Great Minds in Research - Honorable Mention
Multi-disciplinary Biopsychosocial Approach in Low Back Pain Benchmark Study
No full textLow back pain (LBP) is the third most common reason people seek care in America and is the primary reason for missed work days. Working in a pain clinic for eight years and managing research studies directed toward improving low back pain in patients was the motivation for choosing the evidence based intervention in this population. The health care professionals (HCP) in the pain clinic usually have a conversation with the patients who have acute or subacute onset of LBP about their disease and give them a written handout with exercises and ask them to perform these exercises at home. As well, they may be prescribed physical therapy or chiropractic care. From personal clinical experience and descriptions in the literature, patients are fearful of performing exercise on their own and do not feel engaged in the process. Observing the disconnect in the patient’s behavior led to the question: In adult patients with low back pain (P) how does the use of a multi-disciplinary biopsychosocial educational approach (I) compared to written educational materials (C) affect pain intensity (O) with twelve weeks of intervention (T) in a pain clinic?
Current guidelines recommend a multi-disciplinary approach with education including self-management instruction, physical therapy/activity, anti-inflammatory medications, and reassurance about the patient’s prognosis along with feedback. The gap in research is how to translate our knowledge in implementing a multidisciplinary approach to an individualized level. For these reasons, the author sought out evidence to support a change in the current practice at a pain clinic
The Mystery of the Missing Half: The Developing Female Investigator Trope in Detective Fiction
No full textWhile mainstream thought considers Poe’s C. Auguste Dupin to be the first detective with Murders in the Rue Morgue his debut appearance, the female detective trope has her origin in E.T.A. Hoffman’s Das Fräulein von Scuderi. Despite her vintage, the mademoiselle’s role as investigator was overshadowed by her male counterparts in detective fiction, first in time not here being first in right. In subsequent detective fiction a la Poe, the female’s role is typically that of a body—a victim or a corpse exploited by both author and character alike, crimes against who throws a patriarchal world into disorder (e.g., McChesney 3). The male detective must then solve the crime restoring order. This portrayal of gendered roles in the Anglo-American rendition of the genre is artificial, resulting in an imbalanced genre reflecting and reinforcing a patriarchal society at large. Yet the female in detective fiction is changing. New (and old) female sleuths present more-balanced characters, employing both the cold logic used by their male counterparts and their very own, very distinctive modus operandi. These female detectives balance science and superstition, reason and emotion, and restore not only order but also balance to a world thrown into chaos. Most importantly, more female detectives act in complimentary concert with male counterparts presenting balanced lives. Most importantly, when the female investigator appears in heavily male-dominated, machista cultures, her role is also a vehicle for protest and demand for social change
Impairment of Cycling Capacity in the Heat in Well-Trained Endurance Athletes After High-Intensity Short-Term Heat Acclimation
No full textPURPOSE: To investigate the effects of short-term, high-intensity interval training (HIIT) on heat acclimation (HA).METHODS: Male cyclists/triathletes were assigned into either an HA (n = 13) or a comparative (COMP, n = 10) group. HA completed 3 cycling heat-stress tests to exhaustion (60% Wmax) (HST1, pre-HA; HST2, post-HA; HST3, 7 d post-HA). HA consisted of 30-min bouts of HIIT cycling (6 min at 50% Wmax then 12 x 1 min 100%-Wmax bouts with 1 min rest between bouts) on 5 consecutive days. COMP completed HST1 and HST2 only. HST and HA trials were conducted in 35°C/50% relative humidity. Cycling capacity and physiological and perceptual data were recorded.RESULTS:: Cycling capacity was impaired after HIIT HA (77.2 ± 34.2 min vs 56.2 ± 24.4 min, P = .03) and did not return to baseline after 7 d of no HA (59.2 ± 37.4 min). Capacity in HST1 and HST2 was similar in COMP (43.5 ± 8.3 vs 46.8 ± 15.7 min, P = .54). HIIT HA lowered resting rectal (37.0°C ± 0.3°C vs 36.8°C ± 0.2°C, P = .05) and body temperature (36.0°C ±0.3°C vs 35.8°C ± 0.3°C, P = .03) in HST2 compared with HST1 and lowered mean skin temperature (35.4°C ± 0.5°C vs 35.1°C ± 0.3°C, P = .02) and perceived strain on day 5 compared with day 1 of HA. All other data were unaffected.CONCLUSIONS: Cycling capacity was impaired in the heat after 5 d of consecutive HIIT HA despite some heat adaptation. Based on the data, this approach is not recommended for athletes preparing to compete in the heat; however, it is possible that it may be beneficial if a state of overreaching is avoided.© 2019, Human Kinetics. This is an author produced version of a paper published in INTERNATIONAL JOURNAL OF SPORTS PHYSIOLOGY AND PERFORMANCE uploaded in accordance with the publisher’s self- archiving policy. The final published version (version of record) is available online at the link below. Some minor differences between this version and the final published version may remain. We suggest you refer to the final published version should you wish to cite from it
The evolution and stratigraphic architecture of fluvio-lacustrine deltas: reservoir characteristics from the Red River Delta, Lake Texoma and the Denton Creek Delta, Grapevine Lake, TX
No full textElongate, single-channel, non-bifurcating deltas are currently forming in many lakes throughout the United States. The Red River Delta forms an elongate, single-delta into Lake Texoma, sourced by a sand-rich, bedload dominated river system. Current models of delta formation suggest muddy rivers can form elongate deltas due to a lack of sand to form mouth bars, driving bifurcation, but do not explain a mechanism for a sandy river to form a non-bifurcating delta. We propose a model for elongate, single-channel deltas based on a process of grain-size separation within the delta channel, resulting in a sand starved river mouth that cannot bifurcate. Our results indicate that elongate, non-bifurcating deltas should be formed by muddy and sandy rivers alike, and therefore may represent the default delta. Field mapping at Lake Texoma and Grapevine Lake show that these single-channel deltas are found to be associated with overbank sand sheets that emanate laterally from the channel axis. These wings are interpreted to be blowout wings (after Tomanka, 2013) and are a modern example of lacustrine hyperpycnites (after Zavala, 2006). These wings are thin (10-40 cm) and laterally continuous, with lengths and widths spanning several hundred meters from the channel, and aspect ratios reaching 2,480 m wide per 1 m thickness. Blowout wings are found to scale to the formative depositional system, with dimensions corresponding to 5 times the channel width. The recognition of blowout wings greatly increases the potential static connectivity of fluvial bodies by connecting otherwise isolated channels through a network of laterally extensive wings. Adding blowout wings into the lexicon of high-accommodation fluvial depositional models should be considered for subsurface exploration
Progressive hyperthermia elicits distinct responses in maximum and rapid torque production
No full textObjectivesTo investigate the effect of progressive whole-body hyperthermia on maximal, and rapid voluntary torque production, and their neuromuscular determinants.DesignRepeated measures, randomised.MethodsNine participants performed sets of neuromuscular assessments in HOT conditions (~50°C, ~35% relative humidity) at rectal temperatures (Tre) of 37, 38.5 and 39.5°C and in CON conditions (~22°C, ~5% relative humidity) at a Tre of ~37°C and pre-determined comparative time-points. Electrically evoked twitch (single impulse) and octet (8 impulses at 300 Hz) responses were measured at rest. Maximum voluntary torque (MVT), surface electromyography (EMG) normalised to maximal M-wave, and voluntary activation (VA) were measured during 3-5 s isometric maximal voluntary contractions. Rate of torque development (RTD) and normalised EMG were measured during rapid voluntary isometric contractions from rest.ResultsAll neuromuscular variables were unaffected by time in CON. In HOT, MVT, normalised EMG at MVT and VA were lower at 39.5°C compared to 37°C (p<0.05). Early- (0-50 ms) and middle- (50-100 ms) phase voluntary RTD were unaffected by increased Tre (p>0.05), despite lower normalised EMG at Tre 39.5°C (p<0.05) in rapid contractions. In contrast, late-phase (100-150 ms) voluntary RTD was lower at 38.5°C and 39.5°C compared to 37°C (p<0.05) in HOT. Evoked twitch and octet RTD increased with increased Tre (p<0.05). ConclusionsHyperthermia reduced late-phase voluntary RTD, likely due to reduced neural drive and the reduction in MVT. In contrast, early- and middle-phase voluntary RTD were unaffected by hyperthermia, likely due to the conflicting effects of reduced neural drive but faster intrinsic contractile properties.© 2021, Sports Medicine Australia. Published by Elsevier Ltd. The attached document (embargoed until 19/03/2023) is an author produced version of a paper published in JOURNAL OF SCIENCE AND MEDICINE IN SPORT uploaded in accordance with the publisher’s self-archiving policy. The final published version (version of record) is available online at the link. Some minor differences between this version and the final published version may remain. We suggest you refer to the final published version should you wish to cite from it.</p
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