122,378 research outputs found
Nuclear factor I genomic binding associates with chromatin boundaries
No full textBACKGROUND: The Nuclear Factor I (NFI) family of DNA binding proteins (also called CCAAT box transcription factors or CTF) is involved in both DNA replication and gene expression regulation. Using chromatin immuno-precipitation and high throughput sequencing (ChIP-Seq), we performed a genome-wide mapping of NFI DNA binding sites in primary mouse embryonic fibroblasts. RESULTS: We found that in vivo and in vitro NFI DNA binding specificities are indistinguishable, as in vivo ChIP-Seq NFI binding sites matched predictions based on previously established position weight matrix models of its in vitro binding specificity. Combining ChIP-Seq with mRNA profiling data, we found that NFI preferentially associates with highly expressed genes that it up-regulates, while binding sites were under-represented at expressed but unregulated genes. Genomic binding also correlated with markers of transcribed genes such as histone modifications H3K4me3 and H3K36me3, even outside of annotated transcribed loci, implying NFI in the control of the deposition of these modifications. Positional correlation between + and - strand ChIP-Seq tags revealed that, in contrast to other transcription factors, NFI associates with a nucleosomal length of cleavage-resistant DNA, suggesting an interaction with positioned nucleosomes. In addition, NFI binding prominently occurred at boundaries displaying discontinuities in histone modifications specific of expressed and silent chromatin, such as loci submitted to parental allele-specific imprinted expression. CONCLUSIONS: Our data thus suggest that NFI nucleosomal interaction may contribute to the partitioning of distinct chromatin domains and to epigenetic gene expression regulation. NFI ChIP-Seq and input control DNA data were deposited at Gene Expression Omnibus (GEO) repository under accession number GSE15844. Gene expression microarray data for mouse embryonic fibroblasts are on GEO accession number GSE15871
Leptopharynx costatus Mermod 1914
No full textLeptopharynx costatus Mermod, 1914 Mermod, G. 1914. Revue Suisse Zool. 22: 31–114. Habitat. Biological crusts, decaying bark, Espeletia leaves, freshwater sponges, guano, moss, soil, tank bromeliads, tree litter. Distribution. Brazil: Amazonas, Janauari Region, 20 km east of Manaus (3°12’53.11’’S 60°02’46.31’’W); outskirts of Manaus (3°09’16.94’’S 60°16’16.76’’W); Rio Negro, Anavilhanas archipielago (2°38’09.53’’S 60°55’33.53’’W). Paraná, Nupélia Field Station near Porto São José (22°45’04.27’’S 53°15’43.82’’W); São Pedro do Paraná (22°43’16.90’’S 53°10’ 10.85’’W). Costa Rica: Guanacaste, Santa Rosa National Park (10°49’49.79’’N 85°42’42.64’’W). Heredia, Braulio Carrillo National Park (10°12’29.50’’N 84°00’52.25’’W). Puntarenas, near Monteverde Cloud Forest Reserve (10°18’28.07’’N 84°47’48.29’’W). Dominican Republic: (18°28’N 69°56’W). Ecuador: (0°00’ S 78°26’W). Mexico: Guerrero: La Joya cave (18°35’13.95’’N 99°33’56.76’’W). Oaxaca, near Ixtlán de Juárez (17°18’48.83’’N 96°28’59.77’’W). Veracruz, in coffee lands near Coatepec (19°25’02.46’’N 96°58’28.02’’W); near Xalapa, Santuario del Bosque de Niebla (19°30’56.50’’N 96°56’41.65’’W). Peru: Loreto, vecinity of Iquitos (3°46’50.45’’S 74°21’05.75’’W). Venezuela: Amazonas, 10 km north of Puerto Ayacucho (5°41’33.29’’N 67°36’18.70’’W); 14 km north of Puerto Ayacucho (5°41’33.29’’N 67°36’18.70’’W); 50 km north of Puerto Ayacucho (6°06’29.45’’S 67°30’07.53’’W); Pavoni (5°41’33.29’’N 67°36’18.70’’W). Apure, near El Sapo (5°41’33.29’’N 67°36’18.70’’W); near Fundo El Tesoro (5°41’33.29’’N 67°36’18.70’’W). Aragua, Biological Station Rancho Grande (10°23’20.36’’N 67°37’07.85’’W); Henri Pittier National Park (10°30’00.05’’N 67°37’33.64’’W); near Ocumare (10°30’00.05’’N 67°37’33.64’’W). Bolívar, 100 km southwest to Cabruta (7°00’29.36’’N 66°05’48.69’’W); outskirts of Village of Raimundo (7°03’33.83’’N 66°55’39.03’’W). Falcón, Morrocoy National Park, near Chichiriviche (10°55’44.17’’N 69°19’44.72’’W). Guárico, near Cabruta (7°38’49.83’’N 66°14’10.58’’W). Mérida, Páramo de Piedras Blancas, near Pico del Águila (8°52’24.71’’N 70°48’31.65’’W). References. Buosi et al. 2014; Durán-Ramírez et al. 2015; Foissner 1995, 1997, 2000, 2016; Foissner et al. 2003; Sigala-Regalado 2011.Published as part of Durán-Ramírez, Carlos Alberto & Mayén-Estrada, Rosaura, 2018, Ciliate species from tank-less bromeliads in a dry tropical forest and their geographical distribution in the Neotropics, pp. 241-257 in Zootaxa 4497 (2) on page 251, DOI: 10.11646/zootaxa.4497.2.5, http://zenodo.org/record/145215
A Multi-Language Comparison of Influences on Author Verification using Character N-Grams
No full textWe create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Debrot, S., Fivaz, G., Mermod, C. et Weber, J.M. — Atlas des poils de mammifères d'Europe. Neuchâtel, Institut de Zoologie de l’Université (22, chemin de Chantemerle, CH 2000 Neuchâtel), 1982
No full textBourlière François. Debrot, S., Fivaz, G., Mermod, C. et Weber, J.M. — Atlas des poils de mammifères d'Europe. Neuchâtel, Institut de Zoologie de l’Université (22, chemin de Chantemerle, CH 2000 Neuchâtel), 1982. In: Revue d'Écologie (La Terre et La Vie), tome 37, n°1, 1983. p. 136
The vanishing author in computer-generated works: a critical analysis of recent Australian case law
No full textAbstract
The use of software is ubiquitous in the creation of many copyright works, yet the requirement in copyright law that every work have a human author who engages in independent intellectual effort means that its use may prevent copyright subsistence. Several recent Australian cases have refocused attention on authorship as an essential criterion of copyright subsistence, and these cases suggest that much computer-produced output may be authorless and thus lack copyright protection. This article, the first in a two-part series, analyses how each case deals with the question of authorship of computer-produced works and why the use of software diminishes copyright protection for a significant number of computer-generated works. The article critiques the application of conventional notions of human authorship developed in the pre-computer age to modern productions and suggests alternative approaches to authorship that satisfy both the major objectives of copyright policy and the need to adapt to the computer age. The article argues that, without a broader judicial approach to authorship of computer-generated works, Parliament must remedy the lacuna in protection for these ‘authorless’ works. Possible solutions for reform are suggested. In a forthcoming article, the author comprehensively examines those reform proposals
Diffusive author(s), cohesive author: Analysis of S/N (1994)
No full textThis study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)
Dissipative Range Scaling of Higher Order Structure Functions for Velocity and Passive Scalars
No full textDifferently to Kolmogorov's second similarity hypothesis, we find that the 2n-th order velocity and scalar structure functions scale with n-th order moment of the energy dissipation and the scalar dissipation, respectively. The origins of this scaling are analyzed by the transport equations of the fourth order velocity and scalar increment moments and by direct numerical simulations
Fast implementation of iterative adaptive approach for wideband unambiguous radar detection
No full textAccepted author manuscriptMicrowave Sensing, Signals & System
Ratio of n-6/n-3 in the diets of beef cattle
No full textEffects of feeding heat-treated canola (C), soybean (S) and flax (F) or mixtures on growth and slaughter characteristics, taste and fatty acid (FA) composition of beef tissue were investigated using 128 crossbred steers to determine the potential of improving the nutritional quality of beef for humans. For Trial 1 (48 steers), dietary treatments were: roasted C, extruded C, roasted S, extruded S, roasted F and extruded F. For Trial 2 (80 steers), the dietary treatments were: S:F (1:1), S:C (1:1), C:F (1:1) and S:F:C (1:1:1), and the oilseeds were processed either by roasting or extruding before mixing. Soybean meal and soybean oil were used to give equivalent lipid and protein contents to each experimental diet. The basal diet consisted of grass silage, barley grain, vitamins and minerals. Steers were fed for a minimum of 100d then slaughtered at a uniform degree of finish. Growth and slaughter characteristics of the steers were only slightly affected by dietary treatment in that the soybean-fed steers consumed more feed and had a higher average daily gain than the canola or flax-fed animals in Trial 1. There was no difference in taste panel parameters for any of the treatments. Inclusion of flax in the diet increased the total n-3 content of meat. Similar results were found for canola and C18:1n-9 although this was not the case for soybean and the n-6 FA. For the n-6 FA in the PL and neutral lipid fractions of the meat samples, levels were correlated with high dietary levels of n-6 or n-9 with low levels of n-3 while for the n-3 FA, levels were correlated with high dietary n-3 levels and low n-6 levels. Oilseed processing method did not have an effect on any fatty acid levels. It is possible to modify the FA composition of beef meat toward a healthier profile by including heat-treated oilseeds in the diet to influence the degree of lipid metabolism in the rumen.ID: S0377840111004007; M3: Article; Accession Number: S0377840111004007; Author: M.A. McNiven (a, ⁎); Author: J.L. Duynisveld (b); Author: T. Turner (a); Author: A.W. Mitchell (a); Affiliation: Department of Health Management, Atlantic Veterinary College, University of PEI, Charlottetown, PEI, Canada C1A 4P3; Affiliation: Agriculture and Agri-Food Canada, Nappan, NS, Canada B0L 1C0; Keyword: Oilseeds; Keyword: Roasted; Keyword: Extruded; Keyword: Fatty acids; Keyword: Healthy fat; Number of Pages: 11; Language: English
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