219 research outputs found

    Is Interchangeability Possible? Understanding and Evaluating the Evidence Base-Implications for Quality and Safety

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    Geno Merli, a board-certified specialist in internal medicine and physical medicine and rehabilitation, is Director of the Jefferson Center for Vascular Disease at Jefferson Medical College and Senior Vice President and Chief Medical Officer at Thomas Jefferson University Hospital. Dr. Merli received his medical degree from Jefferson Medical College and completed his residency in rehabilitation medicine and internal medicine at Thomas Jefferson University Hospital. Dr. Merli is a nationally recognized expert in the areas of prophylaxis for and management of deep-vein thrombosis and pulmonary embolism (DVT/PE), as well as for the medical consultation of surgical patients. His research interests have focused on prophylaxis for DVT/PE and the management of DVT in acute spinal cord injury, total joint replacement, trauma, and high-risk cancer patients. Former editor-in-chief of Internal Medicine, Dr. Merli currently serves on the editorial board of Patient Care, Journal of the Society of Hospital Medicine, and The Hospitalist. He is also a reviewer for the Archives of Internal Medicine, Annals of Internal Medicine, Chest, Journal of Thrombosis and Thrombolysis, Journal of Thrombosis and Hemostasis and JAMA. He is co-editor of the book Medical Management of the Surgical Patient and co-chairs for a national course on the perioperative care of the surgical patient with medical problems. Dr. Merli is a fellow of the American College of Physicians and a member of American Venous Forum, the Society of Hospital Medicine, American Medical Association, Society of Vascular Medicine and Biology, and the International Society of Thrombosis and Hemostasis

    Dr. Geno Merli Honored at Gala

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    Geno J. Merli, MD, ’75, MACP, FHM, FSVM, received the Achievement Award in Medicine at the 23rd Annual Jefferson Gala on November 18, 2025. The award recognizes Dr. Merli’s extraordinary contributions to medical education and vascular medicine over a distinguished five-decade career. Now Senior Vice President and Associate Chief Medical Officer at Thomas Jefferson University Hospital, Dr. Merli has been a cornerstone of Jefferson’s medical community since completing residencies in rehabilitation medicine and internal medicine. He served as Chief Resident in Rehabilitation Medicine in 1978. In the decades since, he has trained generations of physicians and pioneered approaches to managing deep vein thrombosis and pulmonary embolism that have become standard practice nationwide. Since 2013, Dr. Merli has co-hosted “Annals Consult Guys” – a popular web series produced by the American College of Physicians – with Howard H. Weitz, MD, FACP, FACC, the Bernard L. Segal Endowed Professor in Clinical Cardiology at Jefferson. The duo has hosted more than 125 episodes, bringing fresh perspectives to complex medical cases through engaging discussions and in-depth analyses. Dr. Merli has been recognized with several esteemed designations, including Master of the American College of Physicians, Fellow of the Society of Hospital Medicine, and Fellow of the Society for Vascular Medicine. He also chairs the Governance Committee of the Pulmonary Embolism Response Team (PERT) Consortium and holds membership in numerous professional societies dedicated to advancing cardiovascular care. His commitment to innovation in patient care continues today. Most recently, under his leadership, the Division of Vascular Medicine received a $10,000 grant from the Thomas Jefferson University Hospital Women’s Board to launch the CATCHem (Comprehensive Atherosclerosis Treatment Collaborative Health System) program at the Jefferson Vascular Center, part of the Bruce & Robbi Toll Heart and Vascular Institute. This initiative expands access to critical screening and treatment services for patients with peripheral arterial disease, reflecting Dr. Merli’s ongoing dedication to improving outcomes for underserved populations. “The Achievement Award in Medicine is a muchdeserved recognition not only of Dr. Merli’s remarkable clinical and educational achievements but also his mentorship of countless medical students, residents, and fellows who have gone on to leadership positions across the country,” says Charles J. Yeo, MD, FACS, Enterprise Chair of Surgery. “He has made, and continues to make, a lasting impact on our institution, the community, and the field of medicine.

    Grateful Mother Honors Merli: ‘Great Doctor, Even Better Human Being’

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    For Peggy Bertorelli, family has always come first. The 77-year-old has devoted her life to loving and caring for her husband, three children and their spouses, and her eight grandchildren. Recent years have brought heartbreaking changes to her family: the loss of her son, Andrew, following a brief illness in 2021 and her husband, David, in 2024. More than 20 years ago, she nearly lost her daughter, Cristina. Through that ordeal, she met Geno J. Merli, MD. Dr. Merli, who is now celebrating 50 years of service at Jefferson Health, quickly became an honorary member of the Bertorelli clan. In December 2003 – just weeks before Cristina’s wedding – severe blood clots in her abdomen prompted the family to seek emergency treatment at Thomas Jefferson University Hospital. Bertorelli, a retired school nurse who lives in Lincroft, NJ, recalls the feelings of overwhelming fear as they navigated Cristina’s condition, which required them to reschedule her wedding. Bertorelli still vividly remembers Dr. Merli’s role in leading the team that helped Cristina make a full recovery. She appreciates the expert clinical care that was pivotal to restoring Cristina’s health. But she’s equally grateful for Dr. Merli’s compassion, which she says was a source of strength and hope for the entire family. “We met Dr. Merli by chance, and it was instant comfort,” Bertorelli says. “We felt like he truly cared about Cristina.” On Christmas Eve, Bertorelli’s late husband reached out to Dr. Merli for moral support: “He talked to my husband on the phone for 40 minutes to help get him back on track,” she says. “I will never forget that.” Over the past 20 years, she has expressed the family’s gratitude by making an annual gift to honor Dr. Merli and support his work in vascular medicine. “No matter what your career, you have to exude compassion,” she reflects. “It’s something Dr. Merli would have even if he worked at a deli counter. He’s a great doctor but an even better human being.” Someday soon, Bertorelli hopes to bring her grandchildren for a visit. As she puts it, “Dr. Merli needs to see the fruits of his labor – Cristina’s three children who, along with my other five grandchildren, are the light of my life.” To learn more or make a gift online, please visit: jefferson.edu/GiveSurgery or contact Kelly Austin at 215-955-6383 or [email protected]

    sj-pdf-1-vmj-10.1177_1358863X211047270 – Supplemental material for Apixaban Discontinuation for Invasive Or major Surgical procedures (ADIOS): A prospective cohort study

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    Supplemental material, sj-pdf-1-vmj-10.1177_1358863X211047270 for Apixaban Discontinuation for Invasive Or major Surgical procedures (ADIOS): A prospective cohort study by Geno J Merli, Walter K Kraft, Luis H Eraso, Taki Galanis, Lynda J Thomson, Geoffrey O Ouma, Eugene Viscusi, Jerald Z Gong and Edwin Lam in Vascular Medicine</p

    Bleeding with direct oral anticoagulants vs warfarin: clinical experience

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    AbstractThe risk of bleeding in the setting of anticoagulant therapy continues to be re-evaluated following the introduction of a new generation of direct oral anticoagulants (DOACs). Interruption of DOAC therapy and supportive care may be sufficient for the management of patients who present with mild or moderate bleeding, but in those with life-threatening bleeding, a specific reversal agent is desirable. We review the phase 3 clinical studies of dabigatran, rivaroxaban, apixaban, and edoxaban in patients with nonvalvular atrial fibrillation, in the context of bleeding risk and management

    sj-pdf-2-vmj-10.1177_1358863X20987551 – Supplemental material for 2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions)

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    Supplemental material, sj-pdf-2-vmj-10.1177_1358863X20987551 for 2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions) by Mark A. Creager, Naomi M. Hamburg, Keith D. Calligaro, Ana I. Casanegra, Rosario Freeman, Phyllis A. Gordon, Heather L. Gornik, Esther S.H. Kim, Nicholas J. Leeper, Geno J. Merli, Khusrow Niazi, Jeffrey W. Olin, Rene Quiroz, Elona Rrapo Kaso, Suman Wasan, Andrew R. Waxler, Christopher J. White, Khendi White Solaru, Marlene S. Williams, James A. Arrighi and Lisa A. Mendes in Vascular Medicine</p

    sj-pdf-1-vmj-10.1177_1358863X20987551 – Supplemental material for 2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions)

    No full text
    Supplemental material, sj-pdf-1-vmj-10.1177_1358863X20987551 for 2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions) by Mark A. Creager, Naomi M. Hamburg, Keith D. Calligaro, Ana I. Casanegra, Rosario Freeman, Phyllis A. Gordon, Heather L. Gornik, Esther S.H. Kim, Nicholas J. Leeper, Geno J. Merli, Khusrow Niazi, Jeffrey W. Olin, Rene Quiroz, Elona Rrapo Kaso, Suman Wasan, Andrew R. Waxler, Christopher J. White, Khendi White Solaru, Marlene S. Williams, James A. Arrighi and Lisa A. Mendes in Vascular Medicine</p

    The Challenge of Quality

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    From the Acting Chairman of Medicine

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