1,720,967 research outputs found
Risultati della resezione chirurgica del carcinoma polmonare: analisi attuariale secondo il TNM
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Endothoracic sonography with color Doppler availability during video assisted thoracic surgery (videothoracoscopic operative staging with ultrasound color Doppler) for lung cancer staging.
No full textBronchoalveolar lavage and morphology of the airways after cessation of exposure in asthmatic subjects sensitized to toluene diisocyanate.
No full textA pilot study on radioguided biopsy of the sentinel lymph node in patients with non-small cell lung cancer
No full textPharyngeal fistulas following total laryngectomy. Treated with dilatation and fibrin sealant
No full textPharyngeal fistulas following total laryngectomy. Treated with dilatation and fibrin sealan
Tumor angiogenesis and biological markers in resected stage I NSCLC.
No full textObjective: Microvessel count (MC), as a measure of tumor angiogenesis, has been shown to be significantly correlated with metastatic disease in cutaneous, mammary, prostatic, head and neck cancer. We have previously assessed the role of intensity of angiogenesis as predictor of metastasis in surgically resected T1N0M0 NSCLC. We needed to confirm its value, in a prospective larger study on Stage I NSCLC, before its utilization as a prognostic tool for further clinical investigations. Methods: In the present report we prospectively investigated 227 patients (206 males, 21 females, median age 65 years) with Stage I NSCLC treated only by radical surgery between March 1991 and December 1994 with utmost care for some biological characteristics (proliferative activity, the blood vessel invasion, angiogenesis and the p53 protein expression). Results: The operative procedures consisted of 62 pneumonectomies, 148 lobectomies and 17 segmentectomies or wedge resections. With a median follow-up of 36 months (range 15-60), eighty patients have already experienced a local (n = 22) or systemic (n = 58) relapse. Univariate analysis revealed that T factor (T1 versus T2)(P = 0.008) and angiogenesis count (less than or equal to versus > median, 17) (P = 0.0006) were significant predictors of survival. The same variables were also significant predictors of long Disease Free Survival (P = 0.006 and P = 0.004, respectively). On multivariate analysis, however, only the microvessel count retained its level of prognostic significance as regards both overall (P<0.01) and disease-free survival (P<0.01). Conclusions: The present study corroborates the role of angiogenesis in the metastatic spread of NSCLC and emphasizes its value in the identification of patients in whom surgery should be supplemented by systemic treatment. (C) 1997 Elsevier Science B.V
Il tamponamento laringeo nel trattamento delle inalazioni salivari croniche in pazienti portatori di cannula tracheale
No full textIl tamponamento laringeo nel trattamento delle inalazioni salivari croniche in pazienti portatori di cannula tracheal
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