1,721,102 research outputs found

    Diode laser photocoagulation of choroidal neovascular membranes

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    Background. Krypton or argon laser treatment of choroidal neovascularization (CNV) has been shown to be effective in reducing the incidence of severe visual loss. The usefulness of diode laser in the treatment of many chorioretinal disorders is currently under evaluation. Methods. Our study involved 42 eyes of 41 patients affected with CNV which were treated with a near infrared diode laser. Results. The mean follow-up was 10.12 months. Visual acuity improved in 12 eyes (28.6%), did not change in 17 eyes (40.5%) and worsened in 13 eyes (30.2%). Mean visual acuity before treatment was 0.23 and 0.21 after treatment. Recurrent CNV was seen in 13 eyes. In a subgroup of 24 well-defined juxtafoveal or extrafoveal CNVs which underwent direct photocoagulation visual acuity improved in 8 eyes (33.3%), was unchanged in 11 (45.8%) and worsened in 5 (20.9%). Five eyes showed recurrent CNV. Conclusions. Our results appear to support the use of diode laser in the treatment of CNVs. The deeper penetration into the choriocapillaris of the diode wavelength could be effective in blocking CNV by inducing a more extensive chorioretinal atrophy

    When and how to do a grid laser for diabetic macular edema

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    Macular edema is a common feature of posterior segment diseases. It is an expression of abnormal permeability in either retinal vessels (inner blood-retinal barrier) or in the retinal pigment epithelium (outer blood-retinal barrier). It occurs in either a diffuse pattern where the macula appears generally thickened or, in more severe cases, as cystoid edema with the typical petaloid appearance. Grid laser treatment may be useful to reduce macular edema. Spots of 100-250 micrometers in diameter are applied to the whole posterior pole, one to two groups apart. The foveal avascular zone remains untouched. In patients treated bilaterally, areas temporal and nasal to the macula must be spared to prevent the development of deep scotomas. The mechanism yielding positive results with the grid technique is still debated. Among the most reliable hypotheses are: Proliferation of pigment epithelial cells, followed by and improved efficiency of the outer blood-retinal barrier; proliferation of endothelial cells in retinal capillaries followed by an improved efficiency of the inner blood-retinal barrier; improvement of the retinochoroidal exchanges, and finally, release by coagulative necrosis of a factor able to improve the efficiency of the blood-retinal barriers. Lasers with long wavelengths, such as krypton red and diode, are the most appropriate ones to perform grid treatment

    Immediate intraocular pressure response to selective laser trabeculoplasty

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    Background/aims-Selective laser trabeculoplasty targets the pigmented trabecular meshwork cells without damage to the trabecular meshwork architecture in vitro. A study was conducted in vivo of eight eyes with uncontrolled open angle glaucoma to ascertain the immediate intraocular response to selective laser trabeculoplasty. Methods-The trabecular meshwork of each eye was treated 360 degrees with a frequency doubled Q-switched Nd:YAG laser. Intraocular pressure was measured 1, 2, 24 hours and 1, 4, 6 weeks after treatment. Results-The average preoperative intraocular pressure was 26.6 (SD 7) mm Hg (range 18-37). Two hours and 6 weeks respectively after selective trabeculoplasty intraocular pressure was reduced in all the eyes treated with an average fall of 10.6 (5.2) mm Hg or 39.9%. A pressure spike of 10 mm Hg verified in one eye 1 hour after treatment. Conclusions-Selective laser trabeculoplasty decreased intraocular pressure by an amount similar to that achieved with standard trabeculoplasty. Additional study is needed to determine whether the beneficial effect is sustained over a longer period of follow up
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