15 research outputs found

    Case series: Benefit of Angioembolization prior to surgery for Giant fibrous pleural tumors

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    Only 5% of malignant pleural neoplasms are fibrous tumors of the pleura that typically develop from sub-mesothelial mesenchymal tissue of the visceral pleura. When a tumor measures more than 15 cm, it is referred to as a "giant." The best option for treating both benign and malignant neoplasms is surgery. We conducted a retrospective analysis of the three case series of pleural large fibrous tumors. Additionally, we will discuss our experience with pre-surgical Angioembolization, involving implanting coils and plugs, to treat spindle cell neoplasm. Surgery was completed without any issues

    Lipoid Pneumonia: Rare Cause of Pulmonary Fibrosis in Young Person

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    Aspiration of lipid particles into the lungs results in the underdiagnosed condition known as lipoid pneumonia. Although the majority of recorded instances have been linked to the use of laxatives like mineral oil, the condition can also be brought on by other lipids. Here, we present a rare cause of pulmonary fibrosis in young adults

    Solitary Fibrous Tumor of Pleura Arising from Diaphragmatic Pleura: A Rare Disorder

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    Solitary fibrous tumors (SFTs) of the pleura and lung are not very common primary tumors that originate from the sub-mesothelial tissue and usually show a benign clinical course. The diagnosis is made through immunohistochemical analysis. We have reviewed our experience to find a better and improved understanding of this disease

    Tuberculous empyema thoracic -surgical perspective

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    Objective: To find out the difference in outcome of patients undergoing surgery for tuberculous empyema in early V/S late stages of disease. Subjects and Methods: This is a retrospective study of 163 patients of 20-50 years of age who underwent thoracotomy and decortication for tuberculous empyema thoracic from July 2009 to June 2013. Patients were divided into two groups on the basis of their duration of use of Anti-Tuberculosis Therapy (ATT). Group A (n=80) took ATT for 2 months and Group B (n=83) took ATT for 4 months and above. Age less than 20yrs and above 50yrs, poor functional and nutritional status, underlying parenchymal disease, A.T.T. Defaulters and MDR T.B were excluded. Results: There was no mortality in Group A, while 1 mortality occurred in Group B. Mean day of discharge was 5th post-operative day in Group A and 6th in Group B. 7 patients from Group A and 13 patients from Group B had wound complications whereas 5 patients from Group A and 12 from Group B required up to 10 day of hospitalization due to prolonged air leaks. 1 patient from Group B required revision of procedure and ended up with pleurocutaneous window. Conclusion: Operating patients early with T.B Empyema Thoracic carries better results if compared to those operated at a later stage. Patient selection is an important factor. Key to success is adequate intake of A.T.T. dose by the patient

    Urinothorax Presenting As Respiratory Distress After Nephrolithotomy

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    Urinothorax is a rare and an underdiagnosed condition defined as presence of urine in pleural cavity. We report 2 cases that developed Urinothorax post Percutaneous Nephrolithotomy, our experience of their management and clinical outcomes

    Urinothorax Presenting As Respiratory Distress After Nephrolithotomy

    No full text
    Urinothorax is a rare and an underdiagnosed condition defined as presence of urine in pleural cavity. We report 2 cases that developed Urinothorax post Percutaneous Nephrolithotomy, our experience of their management and clinical outcomes

    Unconstrained user authentication on smart phones through ocular images using FHOG and SVM

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    Recently, perioocular region is gaining popularity amongst the biometric community as an alternative approach to other ocular modalities. This is due to easy imaging and localization from facial images. Therefore, the periocular based user authentication techniques suit well for smart phones. This study aims to combine the image processing and machine learning approaches towards designing a user authentication system for smart phones. For doing so, the study uses viola Jones eye detector for perioocular region localization from the facial images taken with smart phone cameras. The study examines the potential of Felzenszwalb’s HOG (FHOG) features combined with support vector machines (SVM) to authenticate the legitimate user of the smart phone. The empirical evaluation of the proposed scheme exhibits promising results on publicly available MICHE – I ocular dataset

    Hematological parameters predicting severity and mortality in COVID-19 patients of Pakistan: a retrospective comparative analysis

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    Background and Objectives: COVID-19 is a global pandemic. In our study, we aimed to utilize the hematological parameters in predicting the prognosis and mortality in COVID-19 patients. Materials and methods: A retrospective, observational study was conducted to include all the admitted patients (n = 191) having COVID-19 Polymerase chain reaction (PCR) positive, and evaluated those for prognosis and disease outcome by utilizing several biochemical and hematological markers. Results: Amongst the patients admitted in the ward versus in the intensive care unit (ICU), there were significant differences in mean hemoglobin (P = 0.003), total leukocyte count (P = 0.001), absolute neutrophil and lymphocyte counts (P < 0.001), absolute monocyte count (P = 0.019), Neutrophil-to-Lymphocyte ratio (NLR) and Lymphocyte-to-Monocyte ratio (LMR) (P < 0.001), Platelet-to-Lymphocyte ratio (PLR) and Lymphocyte-to C-reactive protein ratio (LCR) (P = 0.002), and C-reactive protein (CRP) levels (P < 0.001). Amongst the deceased patients, there was significant leukocytosis (P = 0.008), neutrophilia and lymphopenia (P < 0.001), increased NLR (P = 0.001), decreased LMR (P < 0.001), increased PLR (p = 0.017), decreased LCR (p = 0.003), and elevated CRP level (P < 0.001). A receiver operating characteristic curve obtained for the above parameters showed NLR (AUC: 0.841, PPV: 83.6%) and PLR (AUC: 0.703, PPV: 81.8%) for ICU patients, while NLR (AUC: 0.860, PPV: 91.1%) and PLR (AUC: 0.677, PPV: 87.5%) for the deceased patients had significant accuracy for predicting the disease severity of COVID-19 in comparison to survivors. Conclusion: The inflammatory markers and hematological indices are a good guide for predicting the severity and disease outcome of coronavirus disease. NLR and PLR are elevated in severe disease while LMR and LCR are inversely correlating with disease severity

    Chemometric analysis of porcine, bovine and ovine heparins

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    Journal of Pharmaceutical and Biomedical Analysis, 164, 345–352Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.Heparin is a polysaccharide anticoagulant drug isolated from animal tissues. There have been concerns on the safety and security of the heparin supply chain since 2007-8 when a contamination crisis led to its disruption. The current study applies a suite of modern analytical techniques to porcine, bovine and ovine intestinal mucosal heparins. These techniques include structural analysis by nuclear magnetic resonance spectrometry, disaccharide compositional analysis, bottom-up analysis of tetrasaccharides corresponding to heparin's antithrombin III binding site. Chemometric analysis was then applied to understand how these structural differences to predict the animal/tissue source of heparin and to help detect blending of heparins from various sources.National Institutes of Healthhttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/j.jpba.2018.10.05
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