1,721,952 research outputs found
6345 Personnel, Barta Building
Full text linkIncludes: non-staff [name], room number, and thesis students.Includes page 2-3 of Memo M-859Roster of non-staff 6345 personnel
Minutes of concurrence meeting no. 18
Full text linkAddendum to the minutes of the concurrence meeting held 5 April 1955 adding specifications that were not reported in Division 6 Memo M-3433
Nuclear Factor-kappaB/Rel proteins: a point of convergence of signalling pathways relevant in neuronal function and dysfunction
Full text linkLaboratory Personnel
Full text linkIncludes: D.I.C. staff, academic staff, non-staff, secretaries, receptionists, foremen, administrative assistants, draftsmen, print clerks, photographer, part-time students, thesis student, technicians, laboratory assistants, machinists, guards, stock clerks, lab. helpers, matron, cleaners, and summary.Also includes page 3 of Memo M-1292.Roster of staff and non-staff laboratory personnel
Ultrasonic vocalizations in mice: Relevance for ethologic and neurodevelopmental disorders studies
Full text linkMice use ultrasonic vocalizations (USVs) to communicate each other and to convey their emotional state. USVs have been greatly characterized in specific life phases and contexts, such as mother isolation-induced USVs for pups or female-induced USVs for male mice during courtship. USVs can be acquired by means of specific tools and later analyzed on the base of both quantitative and qualitative parameters. Indeed, different ultrasonic call categories exist and have already been defined. The understanding of different calls meaning is still missing, and it will represent an essential step forward in the field of USVs. They have long been studied in the ethological context, but recently they emerged as a precious instrument to study pathologies characterized by deficits in communication, in particular neurodevelopmental disorders (NDDs), such as autism spectrum disorders. This review covers the topics of USVs characteristics in mice, contexts for USVs emission and factors that modulate their expression. A particular focus will be devoted to mouse USVs in the context of NDDs. Indeed, several NDDs murine models exist and an intense study of USVs is currently in progress, with the aim of both performing an early diagnosis and to find a pharmacological/behavioral intervention to improve patients' quality of life
Redox homeostasis and natural dietary compounds: Focusing on antioxidants of rice (oryza sativa L.)
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DMT1 Expression and Iron Levels at the Crossroads Between Aging and Neurodegeneration
Full text linkIron homeostasis is an essential prerequisite for metabolic and neurological functions throughout the healthy human life, with a dynamic interplay between intracellular and systemic iron metabolism. The development of different neurodegenerative diseases is associated with alterations of the intracellular transport of iron and heavy metals, principally mediated by Divalent Metal Transporter 1 (DMT1), responsible for Non-Transferrin Bound Iron transport (NTBI). In addition, DMT1 regulation and its compartmentalization in specific brain regions play important roles during aging. This review highlights the contribution of DMT1 to the physiological exchange and distribution of body iron and heavy metals during aging and neurodegenerative diseases. DMT1 also mediates the crosstalk between central nervous system and peripheral tissues, by systemic diffusion through the Blood Brain Barrier (BBB), with the involvement of peripheral iron homeostasis in association with inflammation. In conclusion, a survey about the role of DMT1 and iron will illustrate the complex panel of interrelationship with aging, neurodegeneration and neuroinflammation
A TRANSCRIPTIONAL REPRESSOR OF THE INTERLEUKIN-2 GENE MAY ALSO CONTROL APP GENE-EXPRESSION
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