1,720,986 research outputs found
Prolonged survival of stage IV malignant mixed Müllerian tumor of the ovary after carboplatin, mesna, ifosfamide, and cis-platin chemotherapy: case report
No full textMalignant mixed mullerian tumors (MMMT) of the ovary are rare, aggressive and rapidly progressive tumors. According to the available literature, the presence of metastatic disease rarely permits long term survival. We report on a 64-year old patient with stage IV ovarian MMMT who achieved a surgically-documented complete response (CR) after 6 cycles of carboplatin, mesna, ifosfamide, cis-platin. Pelvic recurrence was diagnosed 14 months later; the patient received 6 cycles of the same regimen used as first-line chemotherapy which resulted in a second complete response lasting for 4 months. The patient died 37 months after initial diagnosis due to intestinal occlusion. In the current case Ca 125 was significantly increased at clinical presentation of disease but not at the time of recurrence
Endometrial stromal sarcoma: a clinicopathologic study.
No full textBackground
This study is a clinicopathologic evaluation of five patients with endometrial stromal sarcoma.
Patients and methods
Over a period of 9 years 5 cases of ESS were observed in our Unit. The patients were retrospectively staged according to the FIGO staging system for endometrial cancer. The neoplasm was divided into two groups based on mitotic activity. Patients underwent endouterine curettage, surgery therapy and, except one of them, chemotherapy.
Results
Two patients had low-grade ESS stage Ib and Ic. The other three had high-grade ESS, and were in stage IIIa. Treatment was surgery for all patients, and adjuvant chemotherapy for 4 out of 5. Both patients in stage I are alive, clinically free from the disease, 25 and 36 months after diagnosis. In stage III all patients died 14, 25 and 36 months after diagnosis.
Conclusion
ESS is a rare uterine neoplasm. Histologic grade is the most important prognostic factor.Background: This study is a clinicopathologic evaluation of five patients with endometrial stromal sarcoma. Patients and Methods: Over a period of 9 years 5 cases of ESS were observed in our Unit. The patients were retrospectively staged according to the FIGO staging system for endometrial cancer. The neoplasm was divided into two groups based on mitotic activity. Patients underwent endouterine curettage, surgery therapy and, except one of them, chemotherapy. Results: Two patients had low-grade ESS stage Ib and Ic. The other three had high-grade ESS, and were in stage IIIa. Treatment was surgery for all patients, and adjuvant chemotherapy for 4 out of 5. Both patients in stage I are alive, clinically free from the disease, 25 and 36 months after diagnosis. In stage III all patients died 14, 25 and 36 months after diagnosis. Conclusion: ESS is a rare uterine neoplasm. Histologic grade is the most important prognostic factor
Endometrial stromal sarcoma: a clinicopathologic study
No full textBackground: This study is a clinicopathologic evaluation of five patients with endometrial stromal sarcoma. Patients and Methods: Over a period of 9 years 5 cases of ESS were observed in our Unit. The patients were retrospectively staged according to the FIGO staging system for endometrial cancer The neoplasm was divided into two groups based on mitotic activity. patients underwent endouterine curettage, surgery therapy and, except one of them, chemotherapy. Results: Two patients had low-grade ESS stage Ib and Ic. The: other three had high-grade ESS, and were in stage IIIa. Treatment was surgery for all patients, and adjuvant chemotherapy for 4 out of 5. Both patients in stage I are alive, clinically free from the disease, 25 and 36 months after diagnosis. In stage III all patients died 14, 25 and 36 months after diagnosis. Conclusion: ESS is a rare uterine neoplasm. Histologic grade is the most important prognostic factor
L'isterectomai vaginale nel trattamento della neoplasia endometriale allo stadio iniziale.
No full text
Successful treatment of cervical and simultaneous cervico-isthmic pregnancy with methotrexate
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