148,947 research outputs found
NANOTECHNOLOGY: RISK, ETHICS AND LAW
No full textList of figures, tables and boxes -- List of contributors -- Preface and acknowledgements -- List of acronyms and abbreviations -- 1. Introduction: the challenge of nanotechnologies / Geoffrey Hunt and Michael D. Mehta -- Pt. One. Introducing nanotechnology -- 2. Nanotechnology: from 'wow' to 'yuck'? / Kristen Kulinowski -- 3. Nanotechnology: from Feynman to funding / K. Eric Drexler -- 4. Microsystems and nanoscience for biomedical applications: a view to the future / Linda M. Pilarski, Michael D. Mehta, Timothy Caulfield, Karan V.I.S. Kaler and Christopher J. Backhouse -- 5. Nanotechnoscience and complex systems: the case for nanology / Geoffrey Hunt -- Pt. Two. Regional developments -- 6. Nanotechnologies and society in Japan / Matsuda Masami, Geoffrey Hunt and Obayashi Masayuki -- 7. Nanotechnologies and society in the USA / Kirsty Mills -- 8. Nanotechnologies and society in Europe / Geoffrey Hunt -- 9. Nanotechnologies and society in Canada / Linda Goldenberg -- Pt. Three. Benefits and risks -- 10. From biotechnology to nanotechnology: what can we learn from earlier technologies? / Michael D. Mehta -- 11. Getting nanotechnology right the first time / John Balbus, Richard Denison, Karen Florini and Scott Walsh -- 12. Risk management and regulation in an emerging technology / Roland Clift -- 13. Nanotechnology and nanoparticle toxicity: a case for precaution / C. Vyvyan Howard and December S.K. Ikah -- 14. The future of nanotechnology in food science and nutrition: can science predict its safety? / Árpád Pusztai and Susan Bardocz -- Pt. Four. Ethics and public understanding -- 15. The global ethics of nanotechnology / Geoffrey Hunt -- 16. Going public: risk, trust and public understanding of nanotechnologies / Julie Barnett, Anna Carr and Roland Clift -- 17. Dwarfing the social? Nanotechnology lessons from the biotechnology front / Edna F. Einsiedel and Linda Goldenberg -- Pt. Five. Law and regulation -- 18. Nanotechnologies and the law of patents: a collision course / Siva Vaidhyanathan -- 19. Nanotechnologles and civil liability / Alan Hannah and Geoffrey Hunt -- 20. Nanotechnologies and the ethical conduct of research involving human subjects / Lorraine Sheremeta -- 21. Nanotechnologies and corporate criminal liability / Celia Wells and Juanita Elias -- Pt. Six. Conclusion -- 22. What makes nanotechnologies special? / Michael D. Mehta and Geoffrey Hunt -- Appendix: measurement scales and glossary -- Inde
Deepa Mehta
No full textLa réalisatrice torontoise Deepa Mehta est née et a grandi en Inde et c’est d’abord dans ce pays qu’elle est attirée par le cinéma, comme média et comme forme artistique. Son père est distributeur de films et propriétaire de plusieurs salles de cinéma. Elle émigre au Canada en 1973 et entreprend une carrière dans le cinéma et à la télévision en se faisant remarquer à l’international par son premier long métrage, Sam and Me (1990), où elle explore l’amitié qui se développe entre un homme âgé d..
BIOTECHNOLOGY UNGLUED: SCIENCE, SOCIETY, AND SOCIAL COHESION
No full textAcknowledgments -- Ch. 1. Introduction: the impact of innovations in biotechnology on social cohesion / Michael D. Mehta -- Ch. 2. The impact of agricultural biotechnology on social cohesion / Michael D. Mehta -- Ch. 3. Agricultural biotechnology and developing countries: issues of poverty alleviation, food security, and sustainable development / Jacqueline E.W. Broerse and Joske F.G. Bunders -- Ch. 4. Legitimation crisis: food safety and genetically modified organisms / Christopher K. Vanderpool, Toby A. Ten Eyck, and Craig K. Harris -- Ch. 5. Genetically modified foods in Norway: a consumer perspective / Margareta Wandel -- Ch. 6. Commercializing Iceland: biotechnology, culture, and the information society / Kyle Eischen -- Ch. 7. Biotechnology and social control: the Canadian DNA Data Bank / Neil Gerlach -- Ch. 8. Biotechnology as modern museums of civilization / Annette Burfoot and Jennifer Poudrier -- Ch. 9. The production, diffusion, and use of knowledge in biotechnology: the discovery of BRCA1 and BRCA2 genes / Robert Dalpe, Louise Bouchard, and Daniel Ducharme -- Contributors -- Inde
Gene expression signatures of postnatal depression
No full text<p>This dataset consists of RNA sequencing gene expression data for 137 women with postnatal depression, which are also published in 2021 in the following publication: Mehta, D., Grewen, K., Pearson, B. <em>et al.</em> Genome-wide gene expression changes in postpartum depression point towards an altered immune landscape. <em>Transl Psychiatry</em> 11, 155 (2021). </p>
<p>This dataset was collected by the University of North Carolina, USA, through a University of Queensland grant, obtained by Dr Divya Mehta while employed at UQ. </p>
Nonlinear properties of silicon core optical fibres
No full textSilica optical fibres are renowned for the framework they have set in modern communications systems, sensors, and biotechnology. One particular trend in current research aims to investigate materials with enhanced optical functionality, high optical efficiency, robustness, and a small device footprint. Amongst the many material choices, semiconductors are emerging as a promising route. In this work, optical fibres and semiconductors are elegantly unified to create a hybrid structure with the potential of seamless integration into current fibre infrastructures. Silica capillaries form the fibre templates in which amorphous semiconductor materials such as silicon and/or germanium are impregnated. This thesis will present the first comprehensive description of the fabrication, characterisation, and the implementation of silicon optical fibres for all-optical signal processing. The fibres are fabricated via a novel high pressure chemical deposition procedure. Each fibre is analysed to determine the exact material composition, uniformity, and more importantly the optical quality. Linear and nonlinear optical characterisations are performed experimentally and supported by intensive numerical studies to validate the results.The high nonlinearity of silicon is exploited for all-optical signal processing. Several investigations have been performed to determine key nonlinear coefficients that were previously unknown in these fibres. Nonlinear absorption experiments allowed for the determination of the degenerate and non-degenerate two-photon absorption coefficients, free carrier cross sections, and free carrier lifetimes of a number of silicon fibres. Nonlinear refraction investigations were then used to establish the Kerr nonlinearity. The strength of this parameter allowed for demonstration of strong self-phase and cross-phase modulation effects. With the insight gained in nonlinear absorption and refraction in silicon optical fibres, all-optical amplitude modulation and wavelength switching was demonstrated at ultrafast sub-picosecond speeds
Stereochemical Reassignment of Mehta and Kundu's Spiculoic Acid A Analogue
No full textA close examination of Mehta and Kundu's synthesis of an analogue of spiculoic acid A revealed discrepancies between their proposed
structure and corresponding data. A revised structure is proposed for Mehta and Kundu's analogue after a careful analysis of their key
synthetic transformations and published data
Lipid-soluble Vitamins A, D, and E in HIV-Infected Pregnant women in Tanzania.
No full textThere is limited published research examining lipid-soluble vitamins in human immunodeficiency virus (HIV)-infected pregnant women, particularly in resource-limited settings. This is an observational analysis of 1078 HIV-infected pregnant women enrolled in a trial of vitamin supplementation in Tanzania. Baseline data on sociodemographic and anthropometric characteristics, clinical signs and symptoms, and laboratory parameters were used to identify correlates of low plasma vitamin A (<0.7 micromol/l), vitamin D (<80 nmol/l) and vitamin E (<9.7 micromol/l) status. Binomial regression was used to estimate risk ratios and 95% confidence intervals. Approximately 35, 39 and 51% of the women had low levels of vitamins A, D and E, respectively. Severe anemia (hemoglobin <85 g/l; P<0.01), plasma vitamin E (P=0.02), selenium (P=0.01) and vitamin D (P=0.02) concentrations were significant correlates of low vitamin A status in multivariate models. Erythrocyte Sedimentation Rate (ESR) was independently related to low vitamin A status in a nonlinear manner (P=0.01). The correlates of low vitamin D status were CD8 cell count (P=0.01), high ESR (ESR >81 mm/h; P<0.01), gestational age at enrollment (nonlinear; P=0.03) and plasma vitamins A (P=0.02) and E (P=0.01). For low vitamin E status, the correlates were money spent on food per household per day (P<0.01), plasma vitamin A concentration (nonlinear; P<0.01) and a gestational age <16 weeks at enrollment (P<0.01). Low concentrations of lipid-soluble vitamins are widely prevalent among HIV-infected women in Tanzania and are correlated with other nutritional insufficiencies. Identifying HIV-infected persons at greater risk of poor nutritional status and infections may help inform design and implementation of appropriate interventions
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
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