169 research outputs found
Who I Am – Feminism Revisited: An Overview
Get PDFWho I Am – Feminism Revisited: An Overview Author / Authors : Puja Chakraberty Page no.1 - 8 Discipline : English literature/Gender Studies/ Cultural studies Script/language : English (Roman) Category : Research paper Keywords: feminism, invincible, significance, rebirth, new woman, development, tribute, daredevil
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Grey Matter Etymology and the neuron(e).
Get PDF‘Neuron’ or ‘neurone’? While it is often assumed that these different spellings reflect usage of American versus British English, there are also inconsistencies within these cultural boundaries. Mehta et al. review historical, etymological and linguistic evidence concerning the spelling of ‘neuron(e)’ and conclude that the only correct spelling is ‘neuron’
How does inflammation affect axonal excitability to mechanical stimulation of neurones in the rat pain pathway?
No full textThe hypoxia of high altitude causes restricted fetal growth in chick embryos with the extent of this effect depending on maternal altitudinal status
No full textTDP-43 loss of function-dependent mis-splicing in amyotrophic lateral sclerosis: molecular insights & development of modified U7 snRNA therapies
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Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias.
Get PDFOBJECTIVE: Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disease of motor neurons with a median survival of 2 years. Familial ALS has a younger age of onset than apparently sporadic ALS. We sought to determine whether this younger age of onset is a result of ascertainment bias or has a genetic basis. METHODS: Samples from people with ALS were sequenced for 13 ALS genes. To determine the effect of genetic variation, age of onset was compared in people with sporadic ALS carrying a pathogenic gene variant and those who do not; to determine the effect of family history, we compared those with genetic sporadic ALS and familial ALS. RESULTS: There were 941 people with a diagnosis of ALS, 100 with familial ALS. Of 841 with apparently sporadic ALS, 95 carried a pathogenic gene variant. The mean age of onset in familial ALS was 5.3 years younger than for apparently sporadic ALS (p=6.0×10-5, 95% CI 2.8 to 7.8 years). The mean age of onset of genetic sporadic ALS was 2.9 years younger than non-genetic sporadic ALS (p=0.011, 95% CI 0.7 to 5.2 years). There was no difference between the mean age of onset in genetic sporadic ALS and familial ALS (p=0.097). CONCLUSIONS: People with familial ALS have an age of onset about 5 years younger than those with apparently sporadic ALS, and we have shown that this is a result of Mendelian gene variants lowering the age of onset, rather than ascertainment bias
A Comparative study of undergraduate students on role of education on women empowerment
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Visuomotor and motorvisual priming with different types of set level congruency::Evidence in support of ideomotor theory, and the Planning and Control Model (PCM)
Get PDFPerception can prime action (visuomotor priming), and action can prime perception (motorvisual priming). According to ideomotor theory both effects rely on the overlap of mental representations between perception and action. This implies that both effects get more pronounced the more features they share. We tested this hypothesis by employing in a motorvisual (Exp.1) and in a visuomotor (Exp.2) setting, three different pairs of left/right target stimuli (hand pictures, arrows, and words) varying in how strongly they overlap with the pair of left/right responses. For two stimulus pairs (hands and words) the hypothesis was confirmed: Hand pictures share more features with the responses than words, consequently hand pictures produced a stronger visuomotor and a stronger motorvisual priming effect than words. However, arrow stimuli showed a different pattern: The temporal dynamics of both priming effects, as well as the direction of the effect seen in motorvisual priming, were significant but opposite to that of the hand and word stimuli. This suggests that the arrows' representations were not involved in ideomotor processes, and we propose instead that they were represented in a spatial or scalar fashion, outside the representations assumed in ideomotor theory. The results are discussed in the context of ideomotor theory, and the Planning and Control Model (PCM) of motorvisual priming
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