13 research outputs found
Axisymmetric deformation in a micropolar thermoelastic medium under fractional order theory of thermoelasticity
No full textEffect of biofertilizers on horticultural and yield traits in french bean var. Contender under dry temperate conditions of Kinnaur district of Himachal Pradesh
No full textKinnaur district is known as the dry temperate zone of Himachal Pradesh and is known for off season and quality production of vegetables.In this district of Himachal Pradesh, Natural farming is mostly done with the minimum use of chemical fertilizers. Farmers are unaware of the judicious use of farm yard manure, and biofertilizers due to which yield of the french bean is very low (50-70 q/ha). French bean is one of the most important vegetables intercropped with apple in Kinnaur District. An experiment was conducted during the summer season of 2011 at the Experimental Farm of Vegetable Research Station, Kalpa, Kinnaur, Himachal Pradesh to study the effect of Rhizobium and Phosphorus Solublizing Bacteria (PSB) on the horticultural and yield traits in french bean var. Contender. Six treatments comprising seed treatments (with and without Rhizobium), seed treatment (with and without PSB) along with the combination of 60 % dose of recommended quantity of Calcium Ammonium Nitrate and 75 % dose of recommended quantity of Single Super Phosphate and organic matter were evaluated in a Randomized Complete Block Design (RCBD) with three replications. The results revealed that T5 treatment, i.e. Rhizobium+ PSB+ Organic matter resulted in more number of pods per plant (20), pod length (18 cm) and pod yield/ha (140 q/ha)
Evaluation of genotypes of bell pepper (Capsicum annuum L.) in cold desert zone of Tabo valley of Spiti district of Himachal Pradesh
No full textAvanafil mediated dual inhibition of IKKβ and TNFR1 in an experimental paradigm of Alzheimer’s disease: in silico and in vivo approach
No full textIn Alzheimer's disease pathology, inhibitors of nuclear factor kappa-β kinase subunit β (IKKB) and Tumor necrosis factor receptor 1 (TNFR1) signaling are linked to neuroinflammation-mediated cognitive decline. We explored the role of a phosphodiesterase 5 inhibitor (PDE5I) with dual antagonistic action on IKKB and TNFR1 to inhibit nuclear factor kappa B (NF-kB) and curb neuroinflammation. In the in silico approach, the FDA-approved Zinc 15 library was docked with IKKB and TNFR1. The top compound with dual antagonistic action on IKKB and TNFR1 was selected based on bonding and non-bonding interactions. Further, induced fit docking (IFD), molecular mechanics-generalized Born and surface area (MMGBSA), and molecular dynamic studies were carried out and evaluated. Lipopolysaccharide (LPS) administration caused a neuroinflammation-mediated cognitive decline in mice. Two doses of avanafil were administered for 28 days while LPS was administered for 10 days. Morris water maze (MWM) along with the passive avoidance test (PAT) were carried out. Concurrently brain levels of inflammatory markers, oxidative parameters, amyloid beta (Aβ), IKKB and NF-kB levels were estimated. Avanafil produced good IKKB and TNFR1 binding ability. It interacted with crucial inhibitory amino acids of IKKB and TNFR1. MD analysis predicted good stability of avanafil with TNFR1 and IKKB. Avanafil 6 mg/kg could significantly improve performance in MWM, PAT and oxidative parameters and reduce Aβ levels and inflammatory markers. As compared to avanafil 3 mg/kg, 6 mg/kg dose was found to exert better efficacy against elevated Aβ , neuroinflammatory cytokines and oxidative markers while improving behavioural parameters.Communicated by Ramaswamy H. Sarma.No Full Tex
Elemental Analysis of Nanomaterial Using Photon-Atom Interaction Based EDXRF Technique
No full textPresence of trace amount of foreign impurities (both metallic and non-metallic) in standard salts used for sample preparation and during the synthesis process can alter the physical and chemical behavior of the pure and doped nano-materials. Therefore, it becomes important to determine concentration of various elements present in synthesized nano-material sample. In present work, the elemental and compositional analysis of nano-materials synthesized using various methods has been performed using photon-atom interaction based energy dispersive x-ray fluorescence (EDXRF) technique. This technique due to its multielement analytical capability, lower detection limit, capability to analyze metals and non-metals alike and almost no sample preparation requirements can be utilized for analysis of nano-materials. The EDXRF spectrometer involves a 2.4 kW Mo anode x-ray tube (Pananalytic, Netherland) equipped with selective absorbers as an excitation source and an LEGe detector (FWHM = 150 eV at 5.895 keV, Canberra, US) coupled with PC based multichannel analyzer used to collect the fluorescent x-ray spectra. The analytical results showed good agreements with the expected values calculated on the basis of the precursor used in preparation of nano-materials
Potential of Some Fungal and Bacterial Species in Bioremediation of Heavy Metals
No full textMicroorganisms including fungi and bacteria have been reported to extract heavy metals from wastewater through bioaccumulation and biosorption. An attempt was, therefore, made to isolate bacteria and fungi from sites contaminated with heavy metals for higher tolerance and removal from wastewater. Bacterial and fungal isolates were obtained from the samples collected from Karnal, Ambala and Yamunanagar districts of Haryana using enrichment culture technique. Bacterial and fungal isolates with tolerant up to 100 ppm concentration of heavy metals (Pb, Cd, Cr) were tested for their removal from liquid media containing 50 ppm concentration of Pb, Cd and Cr each. Five fungi (Penicillium chrysogenum, Aspegillus nidulans, Aspergillus flavus, Rhizopus arrhizus, Trichoderma viride) were also included in this study. Fungi Aspergillus nidulans, Rhizopus arrhizus and Trichoderma viride showed maximum uptake capacity of 25.67 mg/g for Pb, 13.15 mg/g for Cd and 2.55 mg/g of Cr, respectively. The maximum uptake capacity of tolerant bacterial isolates - BPb12 and BPb16, BCd5 and BCr14 were observed to be ~ 45 mg/g for Pb, 2.12 mg/g for Cd and 3.29 mg/g for Cr, respectively. This indicated the potential of these identified fungi and bacteria as biosorbent for removal of high concentration metals from wastewater and industrial effluents
Instrumental detection limit and sensitivity of <i>K</i> and <i>L</i> shell X-ray emission lines of <sub>17</sub> Cl, <sub>37</sub> Rb, and <sub>38</sub> Sr elements using PC-WDXRF spectrometer
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Alignment of
No full textAlignment of the L3 (J = 3∕2) subshell vacancy states produced following selective photoionization in the L3 subshells of the 82Pb, 90Th and 92U elements have been investigated through the angular distribution measurements of the emitted L3 subshell X-ray lines. The L3 subshell of 82Pb, 90Th and 92U elements were excited by the incident K X-rays of 37Rb, 41Nb and 42Mo elements from secondary targets, respectively. The K X-rays were obtained from the secondary targets excited by the unpolarized 59.54 keV photons obtained from 241Am point source. The measurements were performed with tri-axial experimental setup over the angular range 90–154∘ by moving the source and keeping the target-detector assembly fixed. The error in the normalization of the L3 subshell X-rays were removed through the uniform mixing of the reference element into primary element and the simultaneous detection of the L3 (J = 3∕2) subshell X-rays from primary element and isotropically emitted K (J = 1∕2) X-rays from reference element without disturbing the experimental setup. The incident photon energy (Ein) from secondary target were selected in such way that BL3 < Ein < BL2, BLi (i = 1–3) being the binding energy of Li subshell. The selective photoionization leads to reduction in the observed anisotropy due to shifting of unaligned vacancies fromthe L1 and L2 (J = 1∕2) subshells to the L3 subshell (J = 3∕2) through the Coster–Kronig (CK) transitions. The present measurements undoubtedly conclude that anisotropy in the L3 subshell X-ray emission, if present, is at the most of the order of theoretical evaluated value. The alignment measurements with and without applied external magnetic field (~0.6 T) does not significantly change the emission of the L3 subshell X-rays
