130,620 research outputs found
Test di permutazione esatti in disegni fattoriali a misure ripetute bilanciati e non bilanciati
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Large interatrial thrombus-in-transit resulting in acute myocardial infarction complicated by atrioventricular block and cardiogenic shock
No full textGetting around in electric vehicles
No full textThe article has presented the electric tilting three-wheel vehicle (ET3WV) developed at the University of Padova, Italy, for urban mobility. It is characterized by an innovative connection between the tilting front module and the nontilting rear module, and by advanced solutions for the electric propulsion system. The design of the mechanical layout, of the traction drives, of the battery, and of the control circuitry of the vehicle were described, and its characteristics and driving performance were reported. Besides excellent performance in terms of acceleration and range, superior lateral stability and good maneuverability were achieved. Further work is mainly addressed to enhance the electric propulsion systems by providing the traction drives with torque control and flux-weakening features, with the latter being helpful for increasing the cruising speed out of the urban area
Long term survival without anticoagulation after aortic valve replacement with a Lillehei-Kaster prosthesis. A case report
No full textPermutation Testing for Isotonic Inference on Association Studies in Genetics
No full textIsotonic inference concerns situations in which a set of parameters is assumed, a priori, to satisfy certain order restrictions. In the most common case, where populations are arranged in ordered groups, the parameter of interest is assumed to change monotonically with the ordering of the groups. It is then reasonable to take account of the order restrictions in making inferences about the group parameters, such as point or interval estimations or significance tests. Isotonic inference represents a statistical tool of great value in many areas of applied research, especially within the fields of genetic epidemiology and molecular genetics. The purpose of this book is to illustrate a new statistical approach to test allelic association and genotype-specific effects in the genetic study of a disease. We deal with population-based association studies via permutation testing and some likelihood-based tests, but comparisons with other methods will also be performed, analysing advantages and disadvantages of each one, particularly with regard to power properties with small sample sizes. We will focus on case-control analyses to study allelic association between marker, disease-gene and environmental factors. Permutation tests, in particular, will be extended to multivariate and more complex studies where we deal with several genes and several alleles together
Test di permutazione multidimensionali in problemi di inferenza isotonica: un'applicazione alla genetica
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Resting microglia react to Aβ42 fibrils but do not detect oligomers or oligomer-induced neuronal damage
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