60,360 research outputs found

    The 1961 Kampong Bukit Ho Swee fire and the making of modern Singapore

    No full text
    By 1970, Singapore’s urban landscape was dominated by high-rise blocks of planned public housing built by the People’s Action Party government, signifying the establishment of a high modernist nation-state. A decade earlier, the margins of the City had been dominated by kampongs, home to semi-autonomous communities of low-income Chinese families which freely built, and rebuilt, unauthorised wooden houses. This change was not merely one of housing but belied a more fundamental realignment of state-society relations in the 1960s. Relocated in Housing and Development Board flats, urban kampong families were progressively integrated into the social fabric of the emergent nation-state. This study examines the pivotal role of an event, the great Kampong Bukit Ho Swee fire of 1961, in bringing about this transformation. The redevelopment of the fire site in the aftermath of the calamity brought to completion the British colonial regime’s ‘emergency’ programmes of resettling urban kampong dwellers in planned accommodation, in particular, of building emergency public housing on the sites of major fires in the 1950s. The PAP’s far greater political resolve, and the timing of and state of emergency occasioned by the scale of the 1961 disaster, enabled the government to rehouse the Bukit Ho Swee fire victims in emergency housing in record time. This in turn provided the HDB with a strategic platform for clearing other kampongs and for transforming their residents into model citizens of the nation-state. The 1961 fire’s symbolic usefulness extended into the 1980s and beyond, in sanctioning the PAP’s new housing redevelopment schemes. The official account of the inferno has also become politically useful for the government of today for disciplining a new generation of Singaporeans against taking the nation’s progress for granted. Against these exalted claims of the fire’s role in the Singapore Story, this study also examines the degree of actual change and continuity in the social and economic lives of the people of Bukit Ho Swee after the inferno. In some crucial ways, the residents continued to occupy a marginal place in society while pondering, too, over the unresolved question of the cause of the fire. These continuities of everyday life reflect the ambivalence with which the citizenry regarded the high modernist state in contemporary Singapore

    HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children.

    No full text
    Heme oxygenase 1 (HO-1) is an essential enzyme induced by heme and multiple stimuli associated with critical illness. In humans, polymorphisms in the HMOX1 gene promoter may influence the magnitude of HO-1 expression. In many diseases including murine malaria, HO-1 induction produces protective anti-inflammatory effects, but observations from patients suggest these may be limited to a narrow range of HO-1 induction, prompting us to investigate the role of HO-1 in malaria infection. In 307 Gambian children with either severe or uncomplicated P. falciparum malaria, we characterized the associations of HMOX1 promoter polymorphisms, HMOX1 mRNA inducibility, HO-1 protein levels in leucocytes (flow cytometry), and plasma (ELISA) with disease severity. The (GT)(n) repeat polymorphism in the HMOX1 promoter was associated with HMOX1 mRNA expression in white blood cells in vitro, and with severe disease and death, while high HO-1 levels were associated with severe disease. Neutrophils were the main HO-1-expressing cells in peripheral blood, and HMOX1 mRNA expression was upregulated by heme-moieties of lysed erythrocytes. We provide mechanistic evidence that induction of HMOX1 expression in neutrophils potentiates the respiratory burst, and propose this may be part of the causal pathway explaining the association between short (GT)(n) repeats and increased disease severity in malaria and other critical illnesses. Our findings suggest a genetic predisposition to higher levels of HO-1 is associated with severe illness, and enhances the neutrophil burst leading to oxidative damage of endothelial cells. These add important information to the discussion about possible therapeutic manipulation of HO-1 in critically ill patients

    Images from the Ho Chi Minh City Alumni Reception, 2019

    No full text
    Complete set of images from the Ho Chi Minh City Alumni Reception. Taken on Thursday 16th of May 2019 at the Pullman Saigon Centre, Ho Chi Minh City, Vietnam. Attendees included Professor Duncan Bentley, Deputy Vice-Chancellor (Academic) and Professor Monica Kennedy, Pro Vice-Chancellor (International)

    FROM PHILOSOPHY TO HO CHI MINH'S IDEOLOGY

    No full text
    Abstract: The article points out that Ho Chi Minh is a typical philosopher whose core is political philosophy, thereby clarifying Ho Chi Minh’s ideology and practicing Ho Chi Minh’s ideology in Vietnam. Keywords: Philosophy, ideology, Ho Chi Minh. Title: FROM PHILOSOPHY TO HO CHI MINH’S IDEOLOGY Author: Dr. Nguyen Thi Hong Hai International Journal of Social Science and Humanities Research ISSN 2348-3156 (Print), ISSN 2348-3164 (online) Vol. 11, Issue 2, April 2023 - June 2023 Page No: 121-126 Research Publish Journals Website: www.researchpublish.com Published Date: 25-April-2023 DOI: https://doi.org/10.5281/zenodo.7861846 Paper Download Link (Source) https://www.researchpublish.com/papers/from-philosophy-to-ho-chi-minhs-ideologyInternational Journal of Social Science and Humanities Research, ISSN 2348-3156 (Print), ISSN 2348-3164 (online), Research Publish Journals, Website: www.researchpublish.co

    Overexpression of Heme Oxygenase-1 Protects Dopaminergic Neurons against 1-Methyl-4-Phenylpyridinium-Induced Neurotoxicity

    No full text
    Heme oxygenase-1 (HO-1) is up-regulated in response to oxidative stress and catalyzes the degradation of pro- oxidant heme to carbon monoxide (CO) , iron, and bilirubin. Intense HO-1 immunostaining in the Parkinsonian brain is demonstrated, indicating that HO-1 may be involved in the pathogenesis of Parkinsonism. We here locally injected adenovirus containing human HO-1 gene (Ad-HO-1) into rat substantia nigra concomitantly with 1-methyl-4- phenylpyridinium (MPP(+)). Seven days after injection of MPP (+) and Ad-HO-1, the brain was isolated for immunostaining and for measurement of dopamine content and inflammatory cytokines. It was found that overexpression of HO-1 significantly increased the survival rate of dopaminergic neurons; reduced the production of tumor necrosis factor alpha (TNF-alpha) and interleukin-1 beta (IL-1beta) in substantia nigra; antagonized the reduction of striatal dopamine content induced by MPP(+); and also up-regulated brain-derived neurotrophic factor (BDNF) and glial cell line -derived neurotrophic factor (GDNF) expression in substantia nigra. Apomorphine-induced rotation after MPP(+) treatment was also inhibited by Ad-HO-1. On the other hand, inhibition of HO enzymatic activity by zinc protoporphyrin-IX facilitated the MPP(+)-induced rotatory behavior and enhanced the reduction of dopamine content. HO-1 overexpression also protected dopaminergic neurons against MPP(+)-induced neurotoxicity in midbrain neuron-glia cocultures. Overexpression of HO-1 increased the expression of BDNF and GDNF in astrocytes and BDNF in neurons. Our results indicate that HO-1 induction exerts neuroprotection both in vitro and in vivo. Pharmacological or genetic approaches targeting HO-1 may represent a promising and novel therapeutic strategy in treating Parkinsonism

    Cooling rates of neutron stars and the young neutron star in the Cassiopeia A supernova remnant

    No full text
    We explore the thermal state of the neutron star in the Cassiopeia A supernova remnant using the recent result of Ho & Heinke that the thermal radiation of this star is well described by a carbon atmosphere model and the emission comes from the entire stellar surface. Starting from neutron star cooling theory, we formulate a robust method to extract neutrino cooling rates of thermally relaxed stars at the neutrino cooling stage from observations of thermal surface radiation. We show how to compare these rates with the rates of standard candles – stars with non-superfluid nucleon cores cooling slowly via the modified Urca process. We find that the internal temperature of standard candles is a well-defined function of the stellar compactness parameter x=rg/R, irrespective of the equation of state of neutron star matter (R and rg are circumferential and gravitational radii, respectively). We demonstrate that the data on the Cassiopeia A neutron star can be explained in terms of three parameters: f?, the neutrino cooling efficiency with respect to the standard candle; the compactness x; and the amount of light elements in the heat-blanketing envelope. For an ordinary (iron) heat-blanketing envelope or a low-mass (? 10?13 M?) carbon envelope, we find the efficiency f?? 1 (standard cooling) for x? 0.5 and f?? 0.02 (slower cooling) for a maximum compactness x? 0.7. A heat blanket containing the maximum mass (?10?8 M?) of light elements increases f? by a factor of 50. We also examine the (unlikely) possibility that the star is still thermally non-relaxe

    Epinnula rex Ho, Motomura, Hata & Chiang

    No full text
    Epinnula rex Ho, Motomura, Hata & Chiang, nomen novum urn:lsid:zoobank.org:act: 689988A0-823E-4EFC-85A8-2D485860BC3B Type series. As listed in Ho et al. (2017). Other materials. KAUM –I. 117161, 468.0 mm SL, Ishigaki Island, Yaeyama Islands, Okinawa Prefecture, Japan, 24 July 2018, coll. H. Hirasaka; KAUM –I. 141344, 820.0 mm SL, Ishigaki Island, 630–660 m depth, 5 Mar. 2017, H. Hirasaka; KAUM –I. 164522, 190.2 mm SL, Kumano-nada, off Kiinagashima, Kihoku, Mie Prefecture, Japan, 34°10′53″N, 136°21′16″E, 15 Dec. 2015; KAUM –I. 165071, 194.2 mm SL, Enshu-nada, off Omaezaki, Aichi Prefecture, Japan, 34°22′N, 138°11′E, 25 Dec. 2020, FRV Daihachi-tokai-maru; NMMB-P 20645, 285 mm SL, Daxi, Yilan, 22 Oct. 2011, coll. H.-C. Ho. NMMB-P 34200, 471 mm SL, Keelung fish market, 26 May 2020, coll. C.N. Tang; NSMT-P 143547, 736.9 mm SL, Ishigaki Island, 9 Dec. 2021, coll. H. Hirasaka. Etymology. The specific name means “king” in Latin, used as a noun, as an homage to its Atlantic congener Epinnula magistralis which was named for “master” in Latin. Remarks. Although being treated as a subspecies of what is now recognized as Neoepinnula orientalis, Grey (1953) pointed out the differences between E. o. pacifica (from Japan) and E. o. orientalis (from South Africa), which may be recognized as two different species after further study. The availability of Epinnula o. pacifica (now under Neoepinnula) requires that the 2017 E. pacifica have an amended name under the principle of homonymy. As such, a replacement name is provided. The new replacement name will take the same type series, as well as the same authorship with one change. For this nomen novum, we would like to correct the name of the fourth author (WCC) whose surname should be changed to Chiang.Published as part of Ho, Hsuan-Ching, Motomura, Hiroyuki, Hata, Harutaka & Chiang, Wei-Chuan, 2022, Epinnula rex nom. nov., a replacement name for Epinnula pacifica Ho, Motomura Hata & Jiang, 2017 (Teleostei: Gempylidae), pp. 199-200 in Zootaxa 5141 (2) on page 199, DOI: 10.11646/zootaxa.5141.2.8, http://zenodo.org/record/658172

    Factors influencing the continuance intention of Momo e-wallet: An empirical study using sem in Can Tho and Ho Chi Minh City

    No full text
    The research aims to identify the factors that influence continuance intention towards the MoMo e-wallet of customers living in Can Tho and Ho Chi Minh City. This study extends the Theory of Planned Behavior and Technology Acceptance Model by integrating situational normality and security perceptions in fintech adoption. Using a convenient sampling technique, the author has collected data from 248 respondents in Can Tho and Ho Chi Minh City, then proceeded to analyze the data to achieve research objectives. Accordingly, descriptive statistics, Cronbach’s Alpha reliability test, confirmatory factor analysis and structural equation modeling analysis methods were performed thoughout the thesis. The results reveal that all thirteen hypothesized paths are statistically significant. Out of the accepted results, Trust significantly impacts continuance intention (β = 0.58, p < 0.01), while perceived security has a moderate effect (β = 0.41, p < 0.05), are the most profound because they explain the success of MoMo in the highly competitive market of fintech and banking apps. Also, there is a significant means difference in terms of continuance intention among people in Can Tho City and Ho Chi Minh City

    Low cost high-side gate drive power supply for switched reluctance machines

    No full text
    Author name used in this publication: K. W. E. ChengAuthor name used in this publication: Ho S. L.Version of RecordPublishedPublisher permissio

    The frog would a-wooing go, oh-ho

    No full text
    voiceCollected by Merlin Mitchell Mrs. May Kennedy McCord Transcribed by Mary C. Parler Springfield, Mo. Sept. 16, 1950 Reel 65, Item 6 Frog Went A-Courtin' The frog would a-wooing go, oh-ho Whether his mother would let him or no Oh-ho. He soon arrived at Miss Mousie's door, Where he'd been so oft before. Said he, Miss Mousie, are you within? Yes, kind sir, just a-sittin' down to spin. Kemo kimo dero where Come a hee come a hie come a ho Come a ramadiddle puddy whiddle Sing song polly won't you kimeo. Oh he took little Mousie upon his knee Says he, my dear, will you marry me? Oh I first must ask Uncle Rat's consent Or else I could not live content Oh Uncle Rat he shook his sides To think his niece should be a bride Kemo Kimo etc. Oh where will the wedding supper be? Down in the meadow by the white-oak tree. Oh what will we have for the wedding supper? Two big beans and bread and butter. When Uncle Rat began to sing The old cat and kittens came a-tumblin' in Oh the old cat grabbed the Rat by the crown The kittens they tumbled the little Mouse down Kemo kimo etc. The frog he jumped into the lake And there was swallowed by a big black snake -more- Frog Went A-Courtin' Reel 65, Item 6 Continued Oh the big black snake he swam to land And there was killed by a big black man. The big black man he went to France And that's the end of my romance Kemo, kimo, etc. again (She uses the oh-ho refrain and repeats the first line as in the first stanza.)Funding for digitization provided by the Arkansas Humanities Council and the Happy Hollow Foundation
    corecore